about
Mathematical modeling identifies inhibitors of apoptosis as mediators of positive feedback and bistabilityVIAF, a conserved inhibitor of apoptosis (IAP)-interacting factor that modulates caspase activationNrdp1-mediated degradation of the gigantic IAP, BRUCE, is a novel pathway for triggering apoptosisThe holo-apoptosome: activation of procaspase-9 and interactions with caspase-3ARTS and Siah collaborate in a pathway for XIAP degradationRegulation of XIAP translation and induction by MDM2 following irradiationUpstream regulatory role for XIAP in receptor-mediated apoptosisA structure-based benchmark for protein-protein binding affinityStructures of BIR domains from human NAIP and cIAP2Caspase 3 attenuates XIAP (X-linked inhibitor of apoptosis protein)-mediated inhibition of caspase 9Human inhibitor of apoptosis proteins: why XIAP is the black sheep of the familyEngineering a dimeric caspase-9: a re-evaluation of the induced proximity model for caspase activationUbiquitin-Mediated Regulation of Cell Death, Inflammation, and Defense of HomeostasisSmall-molecule SMAC mimetics as new cancer therapeuticsRegulation of the intrinsic apoptosis pathway by reactive oxygen speciesFeatures of protein-protein interactions that translate into potent inhibitors: topology, surface area and affinityErythropoietin: powerful protection of ischemic and post-ischemic brainContribution of caspase(s) to the cell cycle regulation at mitotic phaseMolecular mechanism of Reaper-Grim-Hid-mediated suppression of DIAP1-dependent Dronc ubiquitinationCrystal structure of an invertebrate caspaseXIAP Induces NF-κB Activation via the BIR1/TAB1 Interaction and BIR1 DimerizationCrystal Structure of the BIR1 Domain of XIAP in Two Crystal FormsStructural basis for executioner caspase recognition of P5 position in substratesStructure-Based Design, Synthesis, Evaluation, and Crystallographic Studies of Conformationally Constrained Smac Mimetics as Inhibitors of the X-linked Inhibitor of Apoptosis Protein (XIAP) †Mechanism of procaspase-8 activation by c-FLIPLL2′ loop is critical for caspase-7 active site formationThe crystal structure of caspase-6, a selective effector of axonal degenerationRecognition of Smac-mimetic compounds by the BIR domain of cIAP1Substrate-Induced Conformational Changes Occur in All Cleaved Forms of Caspase-6Structural mechanisms of DIAP1 auto-inhibition and DIAP1-mediated inhibition of drICEDiscovery of a Potent Small-Molecule Antagonist of Inhibitor of Apoptosis (IAP) Proteins and Clinical Candidate for the Treatment of Cancer (GDC-0152)Phosphorylation regulates assembly of the caspase-6 substrate-binding groove.Allosteric modulation of caspase 3 through mutagenesisThe structure of XIAP BIR2: understanding the selectivity of the BIR domainsMechanistic insights into CED-4-mediated activation of CED-3X-linked lymphoproliferative syndromes: brothers or distant cousins?Crystal structure of the yeast metacaspase Yca1.Pathogenesis of colorectal carcinoma and therapeutic implications: the roles of the ubiquitin-proteasome system and Cox-2PAC-1 activates procaspase-3 in vitro through relief of zinc-mediated inhibitionNeuronal apoptosis-inhibitory protein does not interact with Smac and requires ATP to bind caspase-9
P2860
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P2860
description
2003 nî lūn-bûn
@nan
2003 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Mechanism of XIAP-mediated inhibition of caspase-9
@ast
Mechanism of XIAP-mediated inhibition of caspase-9
@en
Mechanism of XIAP-mediated inhibition of caspase-9
@en-gb
Mechanism of XIAP-mediated inhibition of caspase-9
@nl
type
label
Mechanism of XIAP-mediated inhibition of caspase-9
@ast
Mechanism of XIAP-mediated inhibition of caspase-9
@en
Mechanism of XIAP-mediated inhibition of caspase-9
@en-gb
Mechanism of XIAP-mediated inhibition of caspase-9
@nl
prefLabel
Mechanism of XIAP-mediated inhibition of caspase-9
@ast
Mechanism of XIAP-mediated inhibition of caspase-9
@en
Mechanism of XIAP-mediated inhibition of caspase-9
@en-gb
Mechanism of XIAP-mediated inhibition of caspase-9
@nl
P2093
P3181
P1433
P1476
Mechanism of XIAP-mediated inhibition of caspase-9
@en
P2093
Daniel J Rigotti
Emad S Alnemri
Eric N Shiozaki
Jijie Chai
Pingwei Li
Robert Fairman
Srinivasa M Srinivasula
Stefan J Riedl
P304
P3181
P356
10.1016/S1097-2765(03)00054-6
P407
P50
P577
2003-02-01T00:00:00Z