Eukaryote-specific insertion elements control human ARGONAUTE slicer activity
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Anatomy of RISC: how do small RNAs and chaperones activate Argonaute proteins?Post-transcriptional gene silencing, transcriptional gene silencing and human immunodeficiency virusEvolutionary conservation and expression of human RNA-binding proteins and their role in human genetic diseaseA prokaryotic twist on argonaute functionA Dynamic Search Process Underlies MicroRNA Targeting.siRNA carrying an (E)-vinylphosphonate moiety at the 5΄ end of the guide strand augments gene silencing by enhanced binding to human Argonaute-2.Generation of catalytic human Ago4 identifies structural elements important for RNA cleavageARGONAUTE PIWI domain and microRNA duplex structure regulate small RNA sorting in Arabidopsis.Structural basis for microRNA targetingThe evolutionary journey of Argonaute proteinsFrom guide to target: molecular insights into eukaryotic RNA-interference machinery.Markov State Models Reveal a Two-Step Mechanism of miRNA Loading into the Human Argonaute Protein: Selective Binding followed by Structural Re-arrangement.Biochemical isolation of Argonaute protein complexes by Ago-APPGW182-Free microRNA Silencing Complex Controls Post-transcriptional Gene Expression during Caenorhabditis elegans Embryogenesis.From early lessons to new frontiers: the worm as a treasure trove of small RNA biologyConformational Dynamics of Ago-Mediated Silencing ProcessesPhosphorylation of Argonaute proteins affects mRNA binding and is essential for microRNA-guided gene silencing in vivo.Importin-β facilitates nuclear import of human GW proteins and balances cytoplasmic gene silencing protein levels.Lessons from Enzyme Kinetics Reveal Specificity Principles for RNA-Guided Nucleases in RNA Interference and CRISPR-Based Genome Editing.Novel Insights into Guide RNA 5'-Nucleoside/Tide Binding by Human Argonaute 2.Structural Analysis of Human Argonaute-2 Bound to a Modified siRNA Guide.Structure/cleavage-based insights into helical perturbations at bulge sites within T. thermophilus Argonaute silencing complexes.Structural basis for the recognition of guide RNA and target DNA heteroduplex by Argonaute.Water-mediated recognition of t1-adenosine anchors Argonaute2 to microRNA targets.Cloning and Identification of Recombinant Argonaute-Bound Small RNAs Using Next-Generation Sequencing.Evaluation and control of miRNA-like off-target repression for RNA interference.Peptide-Based Isolation of Argonaute Protein Complexes Using Ago-APP.Human Argonaute3 has slicer activity.Amide linkages mimic phosphates in RNA interactions with proteins and are well tolerated in the guide strand of short interfering RNAs.microRNAs and Acute Myeloid Leukemia Chemoresistance: A Mechanistic Overview.Reconstitution of RNA Interference Machinery.Nucleic Acid-Binding Assay of Argonaute Protein Using Fluorescence Polarization.Helix-7 in Argonaute2 shapes the microRNA seed region for rapid target recognition.Multivalent Recruitment of Human Argonaute by GW182.Structural Foundations of RNA Silencing by Argonaute.The Slicer Activity of ARGONAUTE1 Is Required Specifically for the Phasing, Not Production, of Trans-Acting Short Interfering RNAs in Arabidopsis.A Seed Mismatch Enhances Argonaute2-Catalyzed Cleavage and Partially Rescues Severely Impaired Cleavage Found in Fish.Dual Strategies for Argonaute2-Mediated Biogenesis of Erythroid miRNAs Underlie Conserved Requirements for Slicing in Mammals.Structural and mechanistic insights into an archaeal DNA-guided Argonaute protein.Exploring PAZ/3'-overhang interaction to improve siRNA specificity. A combined experimental and modeling study.
P2860
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P2860
Eukaryote-specific insertion elements control human ARGONAUTE slicer activity
description
2013 nî lūn-bûn
@nan
2013 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Eukaryote-specific insertion elements control human ARGONAUTE slicer activity
@ast
Eukaryote-specific insertion elements control human ARGONAUTE slicer activity
@en
Eukaryote-specific insertion elements control human ARGONAUTE slicer activity
@en-gb
Eukaryote-specific insertion elements control human ARGONAUTE slicer activity
@nl
type
label
Eukaryote-specific insertion elements control human ARGONAUTE slicer activity
@ast
Eukaryote-specific insertion elements control human ARGONAUTE slicer activity
@en
Eukaryote-specific insertion elements control human ARGONAUTE slicer activity
@en-gb
Eukaryote-specific insertion elements control human ARGONAUTE slicer activity
@nl
altLabel
Eukaryote-Specific Insertion Elements Control Human ARGONAUTE Slicer Activity
@en
prefLabel
Eukaryote-specific insertion elements control human ARGONAUTE slicer activity
@ast
Eukaryote-specific insertion elements control human ARGONAUTE slicer activity
@en
Eukaryote-specific insertion elements control human ARGONAUTE slicer activity
@en-gb
Eukaryote-specific insertion elements control human ARGONAUTE slicer activity
@nl
P2093
P2860
P50
P3181
P1433
P1476
Eukaryote-specific insertion elements control human ARGONAUTE slicer activity
@en
P2093
Artem A Serganov
Daniel Briskin
Manuel Ascano
Pavel Morozov
Satoko Ishibe-Murakami
Tasos Gogakos
P2860
P304
P3181
P356
10.1016/J.CELREP.2013.06.010
P407
P577
2013-06-27T00:00:00Z