about
A novel cereblon modulator recruits GSPT1 to the CRL4(CRBN) ubiquitin ligaseCongenital pancytopenia and absence of B lymphocytes in a neonate with a mutation in the Ikaros genePrediction and validation of protein-protein interactors from genome-wide DNA-binding data using a knowledge-based machine-learning approachThe IKAROS interaction with a complex including chromatin remodeling and transcription elongation activities is required for hematopoiesis.Pomalidomide reverses γ-globin silencing through the transcriptional reprogramming of adult hematopoietic progenitorsRecurrent deletions of IKZF1 in pediatric acute myeloid leukemiaIkaros inhibits megakaryopoiesis through functional interaction with GATA-1 and NOTCH signalingIkaros limits basophil development by suppressing C/EBP-α expression.Early Development of Definitive Erythroblasts from Human Pluripotent Stem Cells Defined by Expression of Glycophorin A/CD235a, CD34, and CD36.IKZF1: a critical role in the pathogenesis of systemic lupus erythematosus?Ikaros: master of hematopoiesis, agent of leukemia.Ikaros represses and activates PU.1 cell-type-specifically through the multifunctional Sfpi1 URE and a myeloid specific enhancer.Normal hematologic parameters and fetal hemoglobin silencing with heterozygous IKZF1 mutationsA dominant-negative isoform of IKAROS expands primitive normal human hematopoietic cells.Immunomodulatory drugs downregulate IKZF1 leading to expansion of hematopoietic progenitors with concomitant block of megakaryocytic maturation
P2860
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P2860
description
2008 nî lūn-bûn
@nan
2008 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
The role of Ikaros in human erythroid differentiation
@ast
The role of Ikaros in human erythroid differentiation
@en
The role of Ikaros in human erythroid differentiation
@en-gb
The role of Ikaros in human erythroid differentiation
@nl
type
label
The role of Ikaros in human erythroid differentiation
@ast
The role of Ikaros in human erythroid differentiation
@en
The role of Ikaros in human erythroid differentiation
@en-gb
The role of Ikaros in human erythroid differentiation
@nl
prefLabel
The role of Ikaros in human erythroid differentiation
@ast
The role of Ikaros in human erythroid differentiation
@en
The role of Ikaros in human erythroid differentiation
@en-gb
The role of Ikaros in human erythroid differentiation
@nl
P2093
P3181
P1433
P1476
The role of Ikaros in human erythroid differentiation
@en
P2093
Anne Murati
Christian Chabannon
Cécile Tonnelle
Florence Bardin
Marilyne Dijon
Michèle Batoz
P304
P3181
P356
10.1182/BLOOD-2007-07-098202
P407
P577
2008-02-01T00:00:00Z