A crucial role for RACK1 in the regulation of glucose-stimulated IRE1alpha activation in pancreatic beta cells
about
Potent and selective inhibitors of the inositol-requiring enzyme 1 endoribonucleaseXenobiotic perturbation of ER stress and the unfolded protein responseResearch advances at the Institute for Nutritional Sciences at Shanghai, ChinaPhenobarbital indirectly activates the constitutive active androstane receptor (CAR) by inhibition of epidermal growth factor receptor signalingToll-like receptor-mediated IRE1α activation as a therapeutic target for inflammatory arthritisThe unfolded protein response in immunity and inflammationRACK1, A multifaceted scaffolding protein: Structure and function.Mammalian endoplasmic reticulum stress sensor IRE1 signals by dynamic clustering.Fortilin binds IRE1α and prevents ER stress from signaling apoptotic cell death.A combined "omics" approach identifies N-Myc interactor as a novel cytokine-induced regulator of IRE1 protein and c-Jun N-terminal kinase in pancreatic beta cells.Overexpression of SIRT1 in mouse forebrain impairs lipid/glucose metabolism and motor function.The unfolded protein response and the phosphorylations of activating transcription factor 2 in the trans-activation of il23a promoter produced by β-glucans4-O-carboxymethyl ascochlorin causes ER stress and induced autophagy in human hepatocellular carcinoma cells.ERLIN2 promotes breast cancer cell survival by modulating endoplasmic reticulum stress pathways.Direct association of unfolded proteins with mammalian ER stress sensor, IRE1βIdentification of small molecules that protect pancreatic β cells against endoplasmic reticulum stress-induced cell death.Differential responses of hepatic endoplasmic reticulum stress and inflammation in diet-induced obese rats with high-fat diet rich in lard oil or soybean oilPKA phosphorylation couples hepatic inositol-requiring enzyme 1alpha to glucagon signaling in glucose metabolism.Direct interaction between scaffolding proteins RACK1 and 14-3-3ζ regulates brain-derived neurotrophic factor (BDNF) transcriptionIRE1 prevents endoplasmic reticulum membrane permeabilization and cell death under pathological conditionsRACK1 promotes non-small-cell lung cancer tumorigenicity through activating sonic hedgehog signaling pathwayBH3-only proteins are part of a regulatory network that control the sustained signalling of the unfolded protein response sensor IRE1α.Neuronal Cbl controls biosynthesis of insulin-like peptides in Drosophila melanogaster.IRE1α is an endogenous substrate of endoplasmic-reticulum-associated degradationA role for protein inhibitor of activated STAT1 (PIAS1) in lipogenic regulation through SUMOylation-independent suppression of liver X receptors.PDIA6 regulates insulin secretion by selectively inhibiting the RIDD activity of IRE1.Nonmuscle myosin IIB links cytoskeleton to IRE1α signaling during ER stress.IRE1-RACK1 axis orchestrates ER stress preconditioning-elicited cytoprotection from ischemia/reperfusion injury in liverEndoplasmic reticulum (ER) stress response and its physiological roles in plants.ER stress and the decline and fall of pancreatic beta cells in type 1 diabetes.Knockout of inositol-requiring enzyme 1α in pro-opiomelanocortin neurons decreases fat mass via increasing energy expenditure.IRE1: ER stress sensor and cell fate executor.Modelling the effect of GRP78 on anti-oestrogen sensitivity and resistance in breast cancer.Molecular signal networks and regulating mechanisms of the unfolded protein response.Endoplasmic reticulum stress, a new wrestler, in the pathogenesis of idiopathic pulmonary fibrosis.Protein disulfide isomerase A6 controls the decay of IRE1α signaling via disulfide-dependent associationA switch from life to death in endoplasmic reticulum stressed β-cells.The binary switch that controls the life and death decisions of ER stressed β cells.Stressed out about obesity: IRE1α-XBP1 in metabolic disorders.The role of the unfolded protein response in diabetes mellitus.
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P2860
A crucial role for RACK1 in the regulation of glucose-stimulated IRE1alpha activation in pancreatic beta cells
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2010 nî lūn-bûn
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2010 թուականին հրատարակուած գիտական յօդուած
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2010 թվականին հրատարակված գիտական հոդված
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2010年の論文
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2010年論文
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2010年論文
@zh-hant
2010年論文
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2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
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name
A crucial role for RACK1 in th ...... ation in pancreatic beta cells
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A crucial role for RACK1 in th ...... ation in pancreatic beta cells
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A crucial role for RACK1 in th ...... ation in pancreatic beta cells
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A crucial role for RACK1 in th ...... ation in pancreatic beta cells
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A crucial role for RACK1 in th ...... ation in pancreatic beta cells
@ast
A crucial role for RACK1 in th ...... ation in pancreatic beta cells
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A crucial role for RACK1 in th ...... ation in pancreatic beta cells
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A crucial role for RACK1 in th ...... ation in pancreatic beta cells
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A crucial role for RACK1 in th ...... ation in pancreatic beta cells
@ast
A crucial role for RACK1 in th ...... ation in pancreatic beta cells
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A crucial role for RACK1 in th ...... ation in pancreatic beta cells
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A crucial role for RACK1 in th ...... ation in pancreatic beta cells
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P2093
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A crucial role for RACK1 in th ...... ation in pancreatic beta cells
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P2093
Dongmei Wu
Qiurong Ding
Randal J Kaufman
P2860
P3181
P356
10.1126/SCISIGNAL.2000514
P407
P577
2010-01-26T00:00:00Z