Shp-1 mediates the antiproliferative activity of tissue inhibitor of metalloproteinase-2 in human microvascular endothelial cells
about
Endorepellin, the angiostatic module of perlecan, interacts with both the α2β1 integrin and vascular endothelial growth factor receptor 2 (VEGFR2): a dual receptor antagonismEndorepellin laminin-like globular 1/2 domains bind Ig3-5 of vascular endothelial growth factor (VEGF) receptor 2 and block pro-angiogenic signaling by VEGFA in endothelial cellsSrc homology 2 (SH2) domain containing protein tyrosine phosphatase-1 (SHP-1) dephosphorylates VEGF Receptor-2 and attenuates endothelial DNA synthesis, but not migrationKnockdown of protein tyrosine phosphatase SHP-1 inhibits G1/S progression in prostate cancer cells through the regulation of components of the cell-cycle machineryThe cell cycle biomarkers: promising research, but do not oversell themMolecular mechanisms of tissue inhibitor of metalloproteinase 2 in the tumor microenvironmentCell-cycle arrest and acute kidney injury: the light and the dark sidesEvaluation of urinary tissue inhibitor of metalloproteinase-2 in acute kidney injury: a prospective observational study.Src homology domain 2-containing protein-tyrosine phosphatase-1 (SHP-1) binds and dephosphorylates G(alpha)-interacting, vesicle-associated protein (GIV)/Girdin and attenuates the GIV-phosphatidylinositol 3-kinase (PI3K)-Akt signaling pathway.Remote Ischemic Preconditioning and Protection of the Kidney--A Novel Therapeutic Option.Discovery and validation of cell cycle arrest biomarkers in human acute kidney injuryThe tissue inhibitors of metalloproteinases (TIMPs): an ancient family with structural and functional diversityTIMP-2 modulates VEGFR-2 phosphorylation and enhances phosphodiesterase activity in endothelial cells.Alterations of cell cycle control proteins SHP‑1/2, p16, CDK4 and cyclin D1 in radioresistant nasopharyngeal carcinoma cellsValidation of cell-cycle arrest biomarkers for acute kidney injury after pediatric cardiac surgery.Biomarkers of AKI: a review of mechanistic relevance and potential therapeutic implications.Urinary biomarkers TIMP-2 and IGFBP7 early predict acute kidney injury after major surgery.An integrin-binding N-terminal peptide region of TIMP-2 retains potent angio-inhibitory and anti-tumorigenic activity in vivo.Endogenous angiogenesis inhibitor blocks tumor growth via direct and indirect effects on tumor microenvironment.Tissue Inhibitor Metalloproteinase-2 (TIMP-2)⋅IGF-Binding Protein-7 (IGFBP7) Levels Are Associated with Adverse Long-Term Outcomes in Patients with AKI.Diagnostic value of urinary tissue inhibitor of metalloproteinase-2 and insulin-like growth factor binding protein 7 for acute kidney injury: a meta-analysis.Antagonism of VEGF-A-induced increase in vascular permeability by an integrin α3β1-Shp-1-cAMP/PKA pathway.TIMP2•IGFBP7 biomarker panel accurately predicts acute kidney injury in high-risk surgical patients.Lipid-like Nanoparticles for Small Interfering RNA Delivery to Endothelial CellsProteoglycans in cancer biology, tumour microenvironment and angiogenesis.Tissue inhibitors of metalloproteinases in cell signaling: metalloproteinase-independent biological activities.TIMP-2 disrupts FGF-2-induced downstream signaling pathways.The tumor microenvironment: regulation by MMP-independent effects of tissue inhibitor of metalloproteinases-2.Clinical Use of the Urine Biomarker [TIMP-2] × [IGFBP7] for Acute Kidney Injury Risk AssessmentUrinary Tissue Inhibitor of Metalloproteinase-2 and Insulin-Like Growth Factor-Binding Protein 7 for Risk Stratification of Acute Kidney Injury in Patients With Sepsis.Role of tyrosine phosphatase SHP-1 in the mechanism of endorepellin angiostatic activity.Clinical significance of leukocyte-associated immunoglobulin-like receptor-1 expression in human cervical cancer.Delivery of small interfering RNA for inhibition of endothelial cell apoptosis by hypoxia and serum deprivation.Normalization of the tumor microenvironment: evidence for tissue inhibitor of metalloproteinase-2 as a cancer therapeutic.What can we expect from biomarkers for acute kidney injury?Predicting acute kidney injury: current status and future challenges.Biomarkers in acute kidney injury - pathophysiological basis and clinical performance.MiR-221/222 promote human glioma cell invasion and angiogenesis by targeting TIMP2.Regulatory effects of Siegesbeckia glabrescens on non-small cell lung cancer cell proliferation and invasion.Modulation of VEGF receptor 2 signaling by protein phosphatases.
P2860
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P2860
Shp-1 mediates the antiproliferative activity of tissue inhibitor of metalloproteinase-2 in human microvascular endothelial cells
description
2006 nî lūn-bûn
@nan
2006 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Shp-1 mediates the antiprolife ...... icrovascular endothelial cells
@ast
Shp-1 mediates the antiprolife ...... icrovascular endothelial cells
@en
Shp-1 mediates the antiprolife ...... icrovascular endothelial cells
@en-gb
Shp-1 mediates the antiprolife ...... icrovascular endothelial cells
@nl
type
label
Shp-1 mediates the antiprolife ...... icrovascular endothelial cells
@ast
Shp-1 mediates the antiprolife ...... icrovascular endothelial cells
@en
Shp-1 mediates the antiprolife ...... icrovascular endothelial cells
@en-gb
Shp-1 mediates the antiprolife ...... icrovascular endothelial cells
@nl
prefLabel
Shp-1 mediates the antiprolife ...... icrovascular endothelial cells
@ast
Shp-1 mediates the antiprolife ...... icrovascular endothelial cells
@en
Shp-1 mediates the antiprolife ...... icrovascular endothelial cells
@en-gb
Shp-1 mediates the antiprolife ...... icrovascular endothelial cells
@nl
P2093
P2860
P3181
P356
P1476
Shp-1 mediates the antiprolife ...... icrovascular endothelial cells
@en
P2093
Beiyang Wei
Cheng-Kui Qu
Hongmei Li
Jeung-Whan Han
Young-Sik Kim
P2860
P304
P3181
P356
10.1074/JBC.M509932200
P407
P577
2006-02-10T00:00:00Z