Identification of novel SH3 domain ligands for the Src family kinase Hck. Wiskott-Aldrich syndrome protein (WASP), WASP-interacting protein (WIP), and ELMO1
about
Phosphorylation of WASP by the Cdc42-associated kinase ACK1: dual hydroxyamino acid specificity in a tyrosine kinaseActivation of the lysosome-associated p61Hck isoform triggers the biogenesis of podosomesRegulation of p73 by Hck through kinase-dependent and independent mechanismsMolecular characterization of WDCP, a novel fusion partner for the anaplastic lymphoma tyrosine kinase ALKMolecular and structural characterization of the SH3 domain of AHI-1 in regulation of cellular resistance of BCR-ABL(+) chronic myeloid leukemia cells to tyrosine kinase inhibitorsGEF what? Dock180 and related proteins help Rac to polarize cells in new waysIdentification of tyrosine residues on ELMO1 that are phosphorylated by the Src-family kinase Hck.Phosphorylated guanine nucleotide exchange factor C3G, induced by pervanadate and Src family kinases localizes to the Golgi and subcortical actin cytoskeletonWIP remodeling actin behind the scenes: how WIP reshapes immune and other functionsDock180 and ELMO1 proteins cooperate to promote evolutionarily conserved Rac-dependent cell migrationPhysical and functional interaction between Hck tyrosine kinase and guanine nucleotide exchange factor C3G results in apoptosis, which is independent of C3G catalytic domainMetformin induces a dietary restriction-like state and the oxidative stress response to extend C. elegans Healthspan via AMPK, LKB1, and SKN-1Dramatic inhibition of osteoclast sealing ring formation and bone resorption in vitro by a WASP-peptide containing pTyr294 amino acidThe SH3 regulatory domain of the hematopoietic cell kinase Hck binds ELMO via its polyproline motif.Individual Src-family tyrosine kinases direct the degradation or protection of the clock protein Timeless via differential ubiquitylation.Endosomal-sorting complexes required for transport (ESCRT) pathway-dependent endosomal traffic regulates the localization of active Src at focal adhesions.Tyrosine phosphorylation of WIP releases bound WASP and impairs podosome assembly in macrophagesAn unexpected role for the clock protein timeless in developmental apoptosisA novel interaction between the SH2 domain of signaling adaptor protein Nck-1 and the upstream regulator of the Rho family GTPase Rac1 engulfment and cell motility 1 (ELMO1) promotes Rac1 activation and cell motility.MOCA induces membrane spreading by activating Rac1.Identification of c-Src tyrosine kinase substrates using mass spectrometry and peptide microarrays.The Wiskott-Aldrich syndrome protein: forging the link between actin and cell activation.Determinants of substrate recognition in nonreceptor tyrosine kinases.Stem cell factor programs the mast cell activation phenotypeHematopoietic cell kinase (HCK) as a therapeutic target in immune and cancer cells.The verprolin family of proteins: regulators of cell morphogenesis and endocytosis.Wiskott-Aldrich Syndrome at the nexus of autoimmune and primary immunodeficiency diseases.Epigenetically upregulated WIPF1 plays a major role in BRAF V600E-promoted papillary thyroid cancer aggressiveness.Signaling networks regulating leukocyte podosome dynamics and function.WIP regulates the stability and localization of WASP to podosomes in migrating dendritic cells.Activation of p61Hck triggers WASp- and Arp2/3-dependent actin-comet tail biogenesis and accelerates lysosomes.BCR-ABL1-induced downregulation of WASP in chronic myeloid leukemia involves epigenetic modification and contributes to malignancy.
P2860
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P248
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P2860
Identification of novel SH3 domain ligands for the Src family kinase Hck. Wiskott-Aldrich syndrome protein (WASP), WASP-interacting protein (WIP), and ELMO1
description
2002 nî lūn-bûn
@nan
2002 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Identification of novel SH3 do ...... cting protein (WIP), and ELMO1
@ast
Identification of novel SH3 do ...... cting protein (WIP), and ELMO1
@en
Identification of novel SH3 do ...... cting protein (WIP), and ELMO1
@en-gb
Identification of novel SH3 do ...... cting protein (WIP), and ELMO1
@nl
type
label
Identification of novel SH3 do ...... cting protein (WIP), and ELMO1
@ast
Identification of novel SH3 do ...... cting protein (WIP), and ELMO1
@en
Identification of novel SH3 do ...... cting protein (WIP), and ELMO1
@en-gb
Identification of novel SH3 do ...... cting protein (WIP), and ELMO1
@nl
prefLabel
Identification of novel SH3 do ...... cting protein (WIP), and ELMO1
@ast
Identification of novel SH3 do ...... cting protein (WIP), and ELMO1
@en
Identification of novel SH3 do ...... cting protein (WIP), and ELMO1
@en-gb
Identification of novel SH3 do ...... cting protein (WIP), and ELMO1
@nl
P2093
P2860
P921
P356
P1476
Identification of novel SH3 do ...... cting protein (WIP), and ELMO1
@en
P2093
Eun Young Kim
Francesca Zappacosta
Margaret Porter Scott
Roland S Annan
W Todd Miller
P2860
P304
P356
10.1074/JBC.M202783200
P407
P577
2002-08-02T00:00:00Z