Protein kinase R (PKR) interacts with and activates mitogen-activated protein kinase kinase 6 (MKK6) in response to double-stranded RNA stimulation
about
Pathogen recognition and inflammatory signaling in innate immune defensesRAX, the PKR activator, sensitizes cells to inflammatory cytokines, serum withdrawal, chemotherapy, and viral infectionHepatitis C Virus NS5A Protein Down-regulates the Expression of Spindle Gene Aspm through PKR-p38 Signaling PathwayDouble-stranded RNA-dependent protein kinase regulates the motility of breast cancer cellsInfluenza A virus nucleoprotein exploits Hsp40 to inhibit PKR activationHematopoietic cell kinase associates with the 40S ribosomal subunit and mediates the ribotoxic stress response to deoxynivalenol in mononuclear phagocytes.Role of protein kinase R in the killing of Leishmania major by macrophages in response to neutrophil elastase and TLR4 via TNFα and IFNβ.Protein kinase regulated by dsRNA downregulates the interferon production in dengue virus- and dsRNA-stimulated human lung epithelial cellsProtein kinase PKR catalytic activity is required for the PKR-dependent activation of mitogen-activated protein kinases and amplification of interferon beta induction following virus infection.RNA interference in biology and diseaseHIV-1 Tat protein enhances the intracellular growth of Leishmania amazonensis via the ds-RNA induced protein PKR.dsRNA-dependent protein kinase PKR and its role in stress, signaling and HCV infection.Protein kinase PKR-dependent activation of mitogen-activated protein kinases occurs through mitochondrial adapter IPS-1 and is antagonized by vaccinia virus E3L.Vaccinia virus E3 suppresses expression of diverse cytokines through inhibition of the PKR, NF-kappaB, and IRF3 pathways.Comparative induction of 28S ribosomal RNA cleavage by ricin and the trichothecenes deoxynivalenol and T-2 toxin in the macrophage.Regulation of vascular smooth muscle proliferation by heparin: inhibition of cyclin-dependent kinase 2 activity by p27(kip1).Spontaneous and Engineered Compensatory HSV Mutants that Counteract the Host Antiviral PKR Response.Sensing herpes: more than toll.Suppression of proinflammatory signal transduction and gene expression by the dual nucleic acid binding domains of the vaccinia virus E3L proteins.Clinical and therapeutic potential of protein kinase PKR in cancer and metabolism.Activation of protein kinase R is required for induction of stress granules by respiratory syncytial virus but dispensable for viral replicationDoxorubicin bypasses the cytoprotective effects of eIF2α phosphorylation and promotes PKR-mediated cell death.Role of p38 MAPK and RNA-dependent protein kinase (PKR) in hepatitis C virus core-dependent nuclear delocalization of cyclin B1.Innate immunity at the mucosal surface: role of toll-like receptor 3 and toll-like receptor 9 in cervical epithelial cell responses to microbial pathogens.Double-stranded RNA-activated protein kinase mediates induction of interleukin-8 expression by deoxynivalenol, Shiga toxin 1, and ricin in monocytes.Down-regulation of p53 by double-stranded RNA modulates the antiviral response.Deoxynivalenol induces p38 interaction with the ribosome in monocytes and macrophages.Peroxisome proliferator-activated receptor gamma-independent activation of p38 MAPK by thiazolidinediones involves calcium/calmodulin-dependent protein kinase II and protein kinase R: correlation with endoplasmic reticulum stress.Mechanism of attenuation of muscle protein degradation induced by tumor necrosis factor-alpha and angiotensin II by beta-hydroxy-beta-methylbutyrate.Dual Kinase Inhibition Affords Extended in vitro Neuroprotection in Amyloid-β Toxicity.
P2860
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P2860
Protein kinase R (PKR) interacts with and activates mitogen-activated protein kinase kinase 6 (MKK6) in response to double-stranded RNA stimulation
description
2004 nî lūn-bûn
@nan
2004 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Protein kinase R (PKR) interac ...... ouble-stranded RNA stimulation
@ast
Protein kinase R (PKR) interac ...... ouble-stranded RNA stimulation
@en
Protein kinase R (PKR) interac ...... ouble-stranded RNA stimulation
@en-gb
Protein kinase R (PKR) interac ...... ouble-stranded RNA stimulation
@nl
type
label
Protein kinase R (PKR) interac ...... ouble-stranded RNA stimulation
@ast
Protein kinase R (PKR) interac ...... ouble-stranded RNA stimulation
@en
Protein kinase R (PKR) interac ...... ouble-stranded RNA stimulation
@en-gb
Protein kinase R (PKR) interac ...... ouble-stranded RNA stimulation
@nl
prefLabel
Protein kinase R (PKR) interac ...... ouble-stranded RNA stimulation
@ast
Protein kinase R (PKR) interac ...... ouble-stranded RNA stimulation
@en
Protein kinase R (PKR) interac ...... ouble-stranded RNA stimulation
@en-gb
Protein kinase R (PKR) interac ...... ouble-stranded RNA stimulation
@nl
P2093
P356
P1476
Protein kinase R (PKR) interac ...... ouble-stranded RNA stimulation
@en
P2093
Aristóbolo M Silva
Mark Whitmore
Xiaoxia Li
Zhengfan Jiang
P304
37670-37676
P356
10.1074/JBC.M406554200
P407
P577
2004-06-30T00:00:00Z