A mitochondrial origin for frontotemporal dementia and amyotrophic lateral sclerosis through CHCHD10 involvement - Wikidata - awgldk - TriplyDB

A mitochondrial origin for frontotemporal dementia and amyotrophic lateral sclerosis through CHCHD10 involvement

A mitochondrial origin for frontotemporal dementia and amyotrophic lateral sclerosis through CHCHD10 involvement

http://www.wikidata.org/entity/Q24299243

about

Recent advances in amyotrophic lateral sclerosis Toward precision medicine in amyotrophic lateral sclerosis Impaired Autophagy and Defective Mitochondrial Function: Converging Paths on the Road to Motor Neuron Degeneration Clinical and genetic basis of familial amyotrophic lateral sclerosis SOD1 misplacing and mitochondrial dysfunction in amyotrophic lateral sclerosis pathogenesis Genes and Pathways Involved in Adult Onset Disorders Featuring Muscle Mitochondrial DNA Instability Oxidative stress and mitochondrial damage: importance in non-SOD1 ALS Mutations in MDH2, Encoding a Krebs Cycle Enzyme, Cause Early-Onset Severe Encephalopathy Gene expression profiling for human iPS-derived motor neurons from sporadic ALS patients reveals a strong association between mitochondrial functions and neurodegeneration.Loss of function CHCHD10 mutations in cytoplasmic TDP-43 accumulation and synaptic integrity Loss of Parkinson's disease-associated protein CHCHD2 affects mitochondrial crista structure and destabilizes cytochrome c Charting Frontotemporal Dementia: From Genes to Networks.Mutant TDP-43 does not impair mitochondrial bioenergetics in vitro and in vivo Protein Quality Control and the Amyotrophic Lateral Sclerosis/Frontotemporal Dementia Continuum Pathogenic p62/SQSTM1 mutations impair energy metabolism through limitation of mitochondrial substrates.Late onset spinal motor neuronopathy is caused by mutation in CHCHD10.CHCH10 mutations in an Italian cohort of familial and sporadic amyotrophic lateral sclerosis patients.Exome sequencing in amyotrophic lateral sclerosis identifies risk genes and pathways.Spectrum of combined respiratory chain defects.Genotype-phenotype relationship in hereditary amyotrophic lateral sclerosis.Distinct Muscle Biopsy Findings in Genetically Defined Adult-Onset Motor Neuron Disorders A multi-center screening trial of rasagiline in patients with amyotrophic lateral sclerosis: Possible mitochondrial biomarker target engagement.Bovine and murine models highlight novel roles for SLC25A46 in mitochondrial dynamics and metabolism, with implications for human and animal health.Mitochondrial targeting sequence variants of the CHCHD2 gene are a risk for Lewy body disorders Preferential PPAR-α activation reduces neuroinflammation, and blocks neurodegeneration in vivo.CHCHD10 mutations promote loss of mitochondrial cristae junctions with impaired mitochondrial genome maintenance and inhibition of apoptosis.Mutation in the novel nuclear-encoded mitochondrial protein CHCHD10 in a family with autosomal dominant mitochondrial myopathy.An insoluble frontotemporal lobar degeneration-associated TDP-43 C-terminal fragment causes neurodegeneration and hippocampus pathology in transgenic mice Rare Variants in Neurodegeneration Associated Genes Revealed by Targeted Panel Sequencing in a German ALS Cohort.Mutational analysis of PRNP in Alzheimer's disease and frontotemporal dementia in China.Motor neuron disease in 2014. Biomarkers for ALS--in search of the Promised Land Genetic causes of amyotrophic lateral sclerosis: new genetic analysis methodologies entailing new opportunities and challenges.Disturbed mitochondrial dynamics and neurodegenerative disorders.Mitochondrial dynamism and the pathogenesis of Amyotrophic Lateral Sclerosis.Mitochondria and endoplasmic reticulum crosstalk in amyotrophic lateral sclerosis.Targeting mitochondrial metal dyshomeostasis for the treatment of neurodegeneration.New ALS-Related Genes Expand the Spectrum Paradigm of Amyotrophic Lateral Sclerosis.Optimization of a 3D Dynamic Culturing System for In Vitro Modeling of Frontotemporal Neurodegeneration-Relevant Pathologic Features.Parkin suppresses Drp1-independent mitochondrial division Genetics of FTLD: overview and what else we can expect from genetic studies.

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A mitochondrial origin for frontotemporal dementia and amyotrophic lateral sclerosis through CHCHD10 involvement

http://www.wikidata.org/entity/Q24299243

description

2014 nî lūn-bûn

@nan

2014 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի օգոստոսին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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name

A mitochondrial origin for fro ...... is through CHCHD10 involvement

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A mitochondrial origin for fro ...... is through CHCHD10 involvement

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A mitochondrial origin for fro ...... is through CHCHD10 involvement

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A mitochondrial origin for fro ...... is through CHCHD10 involvement

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A mitochondrial origin for fro ...... is through CHCHD10 involvement

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A mitochondrial origin for fro ...... is through CHCHD10 involvement

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A mitochondrial origin for fro ...... is through CHCHD10 involvement

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A mitochondrial origin for fro ...... is through CHCHD10 involvement

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A mitochondrial origin for fro ...... is through CHCHD10 involvement

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A mitochondrial origin for fro ...... is through CHCHD10 involvement

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A mitochondrial origin for fro ...... is through CHCHD10 involvement

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Annabelle Chaussenot

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Anne de Septenville

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Annie Verschueren

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Charlotte Cochaud

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Cécile Rouzier

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Gaëlle Augé

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Hiromi Sesaki

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Isabelle Le Ber

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Jean Pouget

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Karine N'Guyen

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P2860

CHCM1/CHCHD6, novel mitochondrial protein linked to regulation of mitofilin and mitochondrial cristae morphology

Functional annotation of heart enriched mitochondrial genes GBAS and CHCHD10 through guilt by association

OPA1 mutations induce mitochondrial DNA instability and optic atrophy 'plus' phenotypes

ChChd3, an inner mitochondrial membrane protein, is essential for maintaining crista integrity and mitochondrial function

Quantitation of mitochondrial dynamics by photolabeling of individual organelles shows that mitochondrial fusion is blocked during the Bax activation phase of apoptosis

Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS

A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

Structural characterization of CHCHD5 and CHCHD7: two atypical human twin CX9C proteins

Protein structure prediction on the Web: a case study using the Phyre server

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2329-2345

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scholarly article

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603473

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10.1093/BRAIN/AWU138

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Pt 8

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137

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Emmanuelle C Genin

Francoise Lespinasse

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2014-08-01T00:00:00Z

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263207011

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24934289

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mitochondrion organization

amyotrophic lateral sclerosis

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4107737

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