Nucleotide exchange factor ECT2 interacts with the polarity protein complex Par6/Par3/protein kinase Czeta (PKCzeta) and regulates PKCzeta activity
about
Ect2 links the PKCiota-Par6alpha complex to Rac1 activation and cellular transformationPolarity in mammalian epithelial morphogenesisCSPP-L Associates with the Desmosome of Polarized Epithelial Cells and Is Required for Normal Spheroid FormationRhoGTPase signalling at epithelial tight junctions: Bridging the GAP between polarity and cancerInhibition of cyclin-dependent kinase 1 induces cytokinesis without chromosome segregation in an ECT2 and MgcRacGAP-dependent mannerPhosphorylation of the cytokinesis regulator ECT2 at G2/M phase stimulates association of the mitotic kinase Plk1 and accumulation of GTP-bound RhoARegulation of the Rac GTPase pathway by the multifunctional Rho GEF Pebble is essential for mesoderm migration in the Drosophila gastrula.Regulation of neural progenitor cell motility by ceramide and potential implications for mouse brain developmentThe guanine nucleotide exchange factor (GEF) Ect2 is an oncogene in human cancer.The prognostic impact of TGF-β1, fascin, NF-κB and PKC-ζ expression in soft tissue sarcomas.Establishment of epithelial polarity--GEF who's minding the GAP?Deregulation of HEF1 impairs M-phase progression by disrupting the RhoA activation cycle.Ceramide regulates atypical PKCzeta/lambda-mediated cell polarity in primitive ectoderm cells. A novel function of sphingolipids in morphogenesis.A transcriptional cross-talk between RhoA and c-Myc inhibits the RhoA/Rock-dependent cytoskeleton.Control of stem cell self-renewal and differentiation by the heterochronic genes and the cellular asymmetry machinery in Caenorhabditis elegans.Identification of novel Ras-cooperating oncogenes in Drosophila melanogaster: a RhoGEF/Rho-family/JNK pathway is a central driver of tumorigenesis.Association of PKCζ expression with clinicopathological characteristics of breast cancer.AMP-18 facilitates assembly and stabilization of tight junctions to protect the colonic mucosal barrierCdc42 and the guanine nucleotide exchange factors Ect2 and trio mediate Fn14-induced migration and invasion of glioblastoma cellsInterdependence of cell attachment and cell cycle signaling.Mechanisms of CDC-42 activation during contact-induced cell polarizationThe guanine nucleotide exchange factors trio, Ect2, and Vav3 mediate the invasive behavior of glioblastoma.RhoGTPases, actomyosin signaling and regulation of the epithelial Apical Junctional Complex.The Role of Ect2 Nuclear RhoGEF Activity in Ovarian Cancer Cell Transformation.Centralspindlin and α-catenin regulate Rho signalling at the epithelial zonula adherens.Elaborating polarity: PAR proteins and the cytoskeleton.Oncogenic Ect2 signaling regulates rRNA synthesis in NSCLC.Dbl3 drives Cdc42 signaling at the apical margin to regulate junction position and apical differentiation.Functions and Mechanisms of Fibroblast Growth Factor (FGF) Signalling in Drosophila melanogaster.Anillin regulates cell-cell junction integrity by organizing junctional accumulation of Rho-GTP and actomyosin.Ect2/Pbl acts via Rho and polarity proteins to direct the assembly of an isotropic actomyosin cortex upon mitotic entry.Nonfunction of the ECT2 gene may cause renal tubulointerstitial injury leading to focal segmental glomerulosclerosis.Shared mechanisms regulate spatiotemporal RhoA-dependent actomyosin contractility during adhesion and cell division.Plk1 regulates contraction of postmitotic smooth muscle cells and is required for vascular homeostasis.Noncoding Transcribed Ultraconserved Region (T-UCR) uc.261 Participates in Intestinal Mucosa Barrier Damage in Crohn's Disease.Pars and polarity: taking control of Rac.The Neutral Sphingomyelinase 2 Is Required to Polarize and Sustain T Cell Receptor Signaling.
P2860
Q24316134-E633DBD2-9314-4E64-B3D7-646D5791BAF0Q26830318-61FB6BD2-8F06-4D5F-878D-35A4F6D640FAQ27301019-6E809209-9AD1-4828-9644-E826AFBD1E6CQ28088461-CF54652A-3BCC-48DB-A9D9-8ACB35B6FF6EQ28268658-98B301B3-C369-40B5-9A0E-713535885970Q28278864-E3BD7993-96DA-4E0E-BA97-7CB598645956Q30487793-65615E43-6EB0-46E0-95F8-597D3671F1F6Q30555676-F1B8D49A-5571-48F7-B247-44F392E7C932Q33827549-ADB745AC-C964-4FCD-94E1-F838DAE24932Q33842051-E3C49F0E-5D8E-4ED2-A7CB-C9807C539677Q33980507-AAD0A084-CBE4-447C-899F-99F4C7BB5E6DQ34407283-12919CD6-0035-4E63-92E3-D3C732539EE5Q34581663-00CE6430-BBBF-4A7B-99EB-A2DA81BF6728Q35029238-B925B620-218A-4928-AB64-6150A2F4AE7EQ35031288-241538D7-D409-48E3-B2E8-E1CB15A357E6Q35060075-449BA9B1-36FD-4585-A30F-F6422964FF75Q35112947-FEEC88A1-2EAC-4E86-BAA8-48B2009BF2F2Q35916602-2761BEBD-3E20-4864-8D09-0C45BB40C4FEQ36452209-9721D7BC-7D84-4F7B-9149-CECE5B7ED809Q36571070-C64DA213-D6C3-4E71-BF18-DCC9659FBC0AQ36825263-478E0F5D-133E-472E-BBBF-F84EEDAC8F91Q37061110-ED8FCB3A-3441-404F-AF1E-D2AE899FD330Q37319461-B63701EF-2106-4683-8861-415F9137ACD0Q37424400-C7D8BE0A-521F-442B-A99F-83EE81CADB77Q37611553-6D4D500D-CC91-44B6-BCC0-A78373150514Q37838101-268F7FBF-1736-4987-A29A-B5B4719A6026Q38705232-279296C1-5B69-4ECA-A959-5E14EAF2ACDDQ39038189-9D8824B5-9F6D-4904-8E27-5F060CACB860Q40044310-5E4B76C3-60A5-40EA-A6B6-60BB9965D691Q40251223-FF2A53ED-5028-42E2-8A0E-B7D85C5D07B3Q41374143-6886014F-3B90-4B55-B5F2-429581171D44Q42096387-06C89C22-57B0-4EC4-B5F7-B7670AB555D6Q47240825-8BB25B4C-39E1-44CD-A822-570FD58D3684Q48152427-5042B5B8-5C32-48D1-BB16-884736D0E53CQ48933269-317BF041-D247-4E90-9448-6912BB49B3ACQ52655656-BA58DBD3-FAFA-4237-B8B7-AD09434C3761Q54921400-B7B694A3-2C59-4C8F-AB2E-96B8EE17171C
P2860
Nucleotide exchange factor ECT2 interacts with the polarity protein complex Par6/Par3/protein kinase Czeta (PKCzeta) and regulates PKCzeta activity
description
2004 nî lūn-bûn
@nan
2004 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Nucleotide exchange factor ECT ...... and regulates PKCzeta activity
@ast
Nucleotide exchange factor ECT ...... and regulates PKCzeta activity
@en
Nucleotide exchange factor ECT ...... and regulates PKCzeta activity
@en-gb
Nucleotide exchange factor ECT ...... and regulates PKCzeta activity
@nl
type
label
Nucleotide exchange factor ECT ...... and regulates PKCzeta activity
@ast
Nucleotide exchange factor ECT ...... and regulates PKCzeta activity
@en
Nucleotide exchange factor ECT ...... and regulates PKCzeta activity
@en-gb
Nucleotide exchange factor ECT ...... and regulates PKCzeta activity
@nl
prefLabel
Nucleotide exchange factor ECT ...... and regulates PKCzeta activity
@ast
Nucleotide exchange factor ECT ...... and regulates PKCzeta activity
@en
Nucleotide exchange factor ECT ...... and regulates PKCzeta activity
@en-gb
Nucleotide exchange factor ECT ...... and regulates PKCzeta activity
@nl
P2093
P2860
P1476
Nucleotide exchange factor ECT ...... and regulates PKCzeta activity
@en
P2093
Hiroshi Ishida
Razi Raziuddin
Xiu-Fen Liu
P2860
P304
P356
10.1128/MCB.24.15.6665-6675.2004
P407
P577
2004-08-01T00:00:00Z