tyk2, prototype of a novel class of non-receptor tyrosine kinase genes
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The Janus kinases (Jaks)Interleukin 12 (IL-12) induces tyrosine phosphorylation of JAK2 and TYK2: differential use of Janus family tyrosine kinases by IL-2 and IL-12Molecular cloning of L-JAK, a Janus family protein-tyrosine kinase expressed in natural killer cells and activated leukocytesA novel interleukin-12 p40-related protein induced by latent Epstein-Barr virus infection in B lymphocytesJanus kinases in immune cell signalingPhosphorylated interferon-alpha receptor 1 subunit (IFNaR1) acts as a docking site for the latent form of the 113 kDa STAT2 proteinKinase-negative mutants of JAK1 can sustain interferon-gamma-inducible gene expression but not an antiviral stateThe ltk gene encodes a novel receptor-type protein tyrosine kinaseA tyrosine kinase profile of prostate carcinomaDirect binding to and tyrosine phosphorylation of the alpha subunit of the type I interferon receptor by p135tyk2 tyrosine kinaseJAK2 associates with the beta c chain of the receptor for granulocyte-macrophage colony-stimulating factor, and its activation requires the membrane-proximal regionAn analysis of vertebrate mRNA sequences: intimations of translational controlThe amino-terminal region of Tyk2 sustains the level of interferon alpha receptor 1, a component of the interferon alpha/beta receptorIdentification of sequences required for the efficient localization of the focal adhesion kinase, pp125FAK, to cellular focal adhesions.Therapeutic targeting of Janus kinasesMechanisms of chronic JAK-STAT3-SOCS3 signaling in obesityThe Hyper-IgE Syndromes: Lessons in Nature, From Bench to BedsideStructure of the murine Jak2 protein-tyrosine kinase and its role in interleukin 3 signal transductionMolecular characterization of an alpha interferon receptor 1 subunit (IFNaR1) domain required for TYK2 binding and signal transductionPhosphorylation and internalization of gp130 occur after IL-6 activation of Jak2 kinase in hepatocytesBiology and clinical management of myeloproliferative neoplasms and development of the JAK inhibitor ruxolitinibThe molecular regulation of Janus kinase (JAK) activationComplex effects of naturally occurring mutations in the JAK3 pseudokinase domain: evidence for interactions between the kinase and pseudokinase domains.STAT1 from the cell membrane to the DNA.Non-receptor tyrosine kinase 2 reaches its lowest expression levels in human breast cancer during regional nodal metastasis.Joys and surprises of a career studying eukaryotic gene expression.Jak/STAT pathways in cytokine signaling and myeloproliferative disorders: approaches for targeted therapies.Cytokine signaling: birth of a pathway.Activated Ki-Ras complements erythropoietin signaling in CTLL-2 cells, inducing tyrosine phosphorylation of a 160-kDa protein.Janus kinase 3: the controller and the controlledMUC16 induced rapid G2/M transition via interactions with JAK2 for increased proliferation and anti-apoptosis in breast cancer cellsTYK2 Promoter Variant and Diabetes Mellitus in the Japanese.JAK Kinases in Health and Disease: An UpdateElf-1 and Stat5 bind to a critical element in a new enhancer of the human interleukin-2 receptor alpha geneA JAK1/JAK2 chimera can sustain alpha and gamma interferon responses.Novel roles for insulin receptor (IR) in adipocytes and skeletal muscle cells via new and unexpected substrates.Adipose stromal cells primed with hypoxia and inflammation enhance cardiomyocyte proliferation rate in vitro through STAT3 and Erk1/2.Regulation of Connexin43 Function and Expression by Tyrosine Kinase 2.Biology and significance of the JAK/STAT signalling pathways.Inteferons pen the JAK-STAT pathway.
P2860
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P2860
tyk2, prototype of a novel class of non-receptor tyrosine kinase genes
description
1990 nî lūn-bûn
@nan
1990 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1990 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
name
tyk2, prototype of a novel class of non-receptor tyrosine kinase genes
@ast
tyk2, prototype of a novel class of non-receptor tyrosine kinase genes
@en
tyk2, prototype of a novel class of non-receptor tyrosine kinase genes
@en-gb
tyk2, prototype of a novel class of non-receptor tyrosine kinase genes
@nl
type
label
tyk2, prototype of a novel class of non-receptor tyrosine kinase genes
@ast
tyk2, prototype of a novel class of non-receptor tyrosine kinase genes
@en
tyk2, prototype of a novel class of non-receptor tyrosine kinase genes
@en-gb
tyk2, prototype of a novel class of non-receptor tyrosine kinase genes
@nl
prefLabel
tyk2, prototype of a novel class of non-receptor tyrosine kinase genes
@ast
tyk2, prototype of a novel class of non-receptor tyrosine kinase genes
@en
tyk2, prototype of a novel class of non-receptor tyrosine kinase genes
@en-gb
tyk2, prototype of a novel class of non-receptor tyrosine kinase genes
@nl
P2093
P1433
P1476
tyk2, prototype of a novel class of non-receptor tyrosine kinase genes
@en
P2093
I Firmbach-Kraft
J J Krolewski
R Dalla-Favera
P304
P407
P577
1990-09-01T00:00:00Z