Rho GTPase and cAMP/protein kinase A signaling mediates myocilin-induced alterations in cultured human trabecular meshwork cells
about
Myocilin is a modulator of Wnt signalingDifferential effects of myocilin and optineurin, two glaucoma genes, on neurite outgrowthProtein expression in human trabecular meshwork: downregulation of RhoGDI by dexamethasone in vitro.Impairment of protein trafficking upon overexpression and mutation of optineurin.Evidence for a role of angiopoietin-like 7 (ANGPTL7) in extracellular matrix formation of the human trabecular meshwork: implications for glaucoma.Wnt activation by wild type and mutant myocilin in cultured human trabecular meshwork cells.Molecular basis for involvement of CYP1B1 in MYOC upregulation and its potential implication in glaucoma pathogenesis.Establishment of inducible wild type and mutant myocilin-GFP-expressing RGC5 cell linesA maladaptive role for EP4 receptors in podocytesEffect of elevated intracellular cAMP levels on actomyosin contraction in bovine trabecular meshwork cells.Effect of PITX2 knockdown on transcriptome of primary human trabecular meshwork cell culturesFocus on molecular events in the anterior chamber leading to glaucoma.Biological properties of trabecular meshwork cells.Dual localization of wild-type myocilin in the endoplasmic reticulum and extracellular compartment likely occurs due to its incomplete secretion.Glaucoma-associated myocilin: a better understanding but much more to learn.Myocilin and Optineurin: Differential Characteristics and Functional ConsequencesFunctional properties of fibronectin in the trabecular meshworkThe effects of myocilin expression on functionally relevant trabecular meshwork genes: a mini-review.Bioactive lysophospholipids: role in regulation of aqueous humor outflow and intraocular pressure in the context of pathobiology and therapy of glaucoma.The dysfunction of the trabecular meshwork during glaucoma course.Role of the Rho GTPase/Rho kinase signaling pathway in pathogenesis and treatment of glaucoma: Bench to bedside research.Rho GTPase signaling and PTH 3-34, but not PTH 1-34, maintain the actin cytoskeleton and antagonize bisphosphonate effects in mouse osteoblastic MC3T3-E1 cells.Elevated amounts of myocilin in the aqueous humor of transgenic mice cause significant changes in ocular gene expression.Recreating a human trabecular meshwork outflow system on microfabricated porous structures.Prenylation of Rho G-proteins: a novel mechanism regulating gene expression and protein stability in human trabecular meshwork cells.
P2860
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P2860
Rho GTPase and cAMP/protein kinase A signaling mediates myocilin-induced alterations in cultured human trabecular meshwork cells
description
2008 nî lūn-bûn
@nan
2008 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Rho GTPase and cAMP/protein ki ...... uman trabecular meshwork cells
@ast
Rho GTPase and cAMP/protein ki ...... uman trabecular meshwork cells
@en
Rho GTPase and cAMP/protein ki ...... uman trabecular meshwork cells
@en-gb
Rho GTPase and cAMP/protein ki ...... uman trabecular meshwork cells
@nl
type
label
Rho GTPase and cAMP/protein ki ...... uman trabecular meshwork cells
@ast
Rho GTPase and cAMP/protein ki ...... uman trabecular meshwork cells
@en
Rho GTPase and cAMP/protein ki ...... uman trabecular meshwork cells
@en-gb
Rho GTPase and cAMP/protein ki ...... uman trabecular meshwork cells
@nl
prefLabel
Rho GTPase and cAMP/protein ki ...... uman trabecular meshwork cells
@ast
Rho GTPase and cAMP/protein ki ...... uman trabecular meshwork cells
@en
Rho GTPase and cAMP/protein ki ...... uman trabecular meshwork cells
@en-gb
Rho GTPase and cAMP/protein ki ...... uman trabecular meshwork cells
@nl
P2093
P2860
P921
P356
P1476
Rho GTPase and cAMP/protein ki ...... uman trabecular meshwork cells
@en
P2093
Beatrice Y J T Yue
Bum-Chan Park
Nirmala SundarRaj
Takahisa Koga
Xiang Shen
P2860
P304
P356
10.1074/JBC.M708250200
P407
P577
2008-01-04T00:00:00Z