Hydroxylation of 5-methylcytosine by TET1 promotes active DNA demethylation in the adult brain
about
Transcriptional and epigenetic mechanisms of addictionThymine DNA glycosylase specifically recognizes 5-carboxylcytosine-modified DNAThymine DNA glycosylase is essential for active DNA demethylation by linked deamination-base excision repairLesion processing by a repair enzyme is severely curtailed by residues needed to prevent aberrant activity on undamaged DNAThymine DNA glycosylase can rapidly excise 5-formylcytosine and 5-carboxylcytosine: potential implications for active demethylation of CpG sitesGenetic deletion of Gadd45b, a regulator of active DNA demethylation, enhances long-term memory and synaptic plasticityHydroquinone increases 5-hydroxymethylcytosine formation through ten eleven translocation 1 (TET1) 5-methylcytosine dioxygenaseTet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosineAdult neurogenesis in the mammalian brain: significant answers and significant questionsDNA demethylation dynamicsSignaling mechanisms regulating adult neural stem cells and neurogenesisAcute depletion of Tet1-dependent 5-hydroxymethylcytosine levels impairs LIF/Stat3 signaling and results in loss of embryonic stem cell identityThe emerging insights into catalytic or non-catalytic roles of TET proteins in tumors and neural developmentWhere Environment Meets Cognition: A Focus on Two Developmental Intellectual Disability DisordersModifiers and Readers of DNA Modifications and Their Impact on Genome Structure, Expression, and Stability in DiseaseMeCP2 and the enigmatic organization of brain chromatin. Implications for depression and cocaine addictionEpigenetic Mechanisms in Developmental Alcohol-Induced Neurobehavioral DeficitsPhysiological and pathological implications of 5-hydroxymethylcytosine in diseasesEpigenetic Alterations in Alzheimer's DiseaseEpigenetic: A missing paradigm in cellular and molecular pathways of sulfur mustard lung: a prospective and comparative studyFunctions of TET Proteins in Hematopoietic TransformationDynamic DNA methylation in the brain: a new epigenetic mark for experience-dependent plasticityTurning over DNA methylation in the mindMechanisms and functions of Tet protein-mediated 5-methylcytosine oxidationEpigenetic mechanisms in experience-driven memory formation and behaviorCancer metabolism: key players in metabolic reprogrammingEpigenetic control on cell fate choice in neural stem cellsDNA modifications: function and applications in normal and disease StatesActive DNA demethylation in post-mitotic neurons: a reason for optimismReprogramming DNA methylation in the mammalian life cycle: building and breaking epigenetic barriersFolate and DNA methylation: a review of molecular mechanisms and the evidence for folate's roleCytosine modifications in neurodevelopment and diseasesEnzymatic DNA oxidation: mechanisms and biological significanceMechanisms of epigenetic regulation of leukemia onset and progressionThe roles of retinoic acid and retinoic acid receptors in inducing epigenetic changesUnlocking epigenetic codes in neurogenesisRegulation of the Epigenome by Vitamin CActive DNA demethylation of the vertebrate genomes by DNA methyltransferases: deaminase, dehydroxymethylase or demethylase?Mechanism and function of oxidative reversal of DNA and RNA methylationMammalian epigenetic mechanisms
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P2860
Hydroxylation of 5-methylcytosine by TET1 promotes active DNA demethylation in the adult brain
description
2011 nî lūn-bûn
@nan
2011 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Hydroxylation of 5-methylcytos ...... methylation in the adult brain
@ast
Hydroxylation of 5-methylcytos ...... methylation in the adult brain
@en
Hydroxylation of 5-methylcytos ...... methylation in the adult brain
@nl
type
label
Hydroxylation of 5-methylcytos ...... methylation in the adult brain
@ast
Hydroxylation of 5-methylcytos ...... methylation in the adult brain
@en
Hydroxylation of 5-methylcytos ...... methylation in the adult brain
@nl
prefLabel
Hydroxylation of 5-methylcytos ...... methylation in the adult brain
@ast
Hydroxylation of 5-methylcytos ...... methylation in the adult brain
@en
Hydroxylation of 5-methylcytos ...... methylation in the adult brain
@nl
P2093
P2860
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Hydroxylation of 5-methylcytos ...... methylation in the adult brain
@en
P2093
Chun Zhong
Junjie U Guo
P2860
P304
P3181
P356
10.1016/J.CELL.2011.03.022
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P5008
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2011-04-29T00:00:00Z