about
O-fucosylation is required for ADAMTS13 secretionADAMTS13 substrate recognition of von Willebrand factor A2 domainA disintegrin-like and metalloprotease (reprolysin-type) with thrombospondin type 1 motif (ADAMTS) superfamily: functions and mechanismsCurrent concepts in thrombotic thrombocytopenic purpuraPathogenesis of thrombotic microangiopathiesProteolytic processing of von Willebrand factor by adamts13 and leukocyte proteasesADAMTS13 and von Willebrand factor in thrombotic thrombocytopenic purpuraAllosteric activation of ADAMTS13 by von Willebrand factor.Shear-Induced Unfolding and Enzymatic Cleavage of Full-Length VWF Multimers.Stall encodes an ADAMTS metalloprotease and interacts genetically with Delta in Drosophila ovarian follicle formation.Attack of the acronyms: TTP, VWF, ADAMTS-13 and SELDI-TOF-MS.Further characterization of ADAMTS-13 inactivation by thrombin.Molecular biology of ADAMTS13 and diagnostic utility of ADAMTS13 proteolytic activity and inhibitor assays.ADAMTS-13 plasma level determination uncovers antigen absence in acquired thrombotic thrombocytopenic purpura and ethnic differences.Inhibitory autoantibodies against ADAMTS-13 in patients with thrombotic thrombocytopenic purpura bind ADAMTS-13 protease and may accelerate its clearance in vivo.An IAP retrotransposon in the mouse ADAMTS13 gene creates ADAMTS13 variant proteins that are less effective in cleaving von Willebrand factor multimers.Degradation of circulating von Willebrand factor and its regulator ADAMTS13 implicates secreted Bacillus anthracis metalloproteases in anthrax consumptive coagulopathy.Effects of naturally occurring mutations in CUB-1 domain on synthesis, stability, and activity of ADAMTS-13.The distal carboxyl-terminal domains of ADAMTS13 are required for regulation of in vivo thrombus formation.The first deletion mutation in the TSP1-6 repeat domain of ADAMTS13 in a family with inherited thrombotic thrombocytopenic purpura.[ADAMTS13, von Willebrand factor specific cleaving protease].Two novel heterozygote missense mutations of the ADAMTS13 gene in a child with recurrent thrombotic thrombocytopenic purpuraConformational activation of ADAMTS13.Adult-onset congenital thrombotic thrombocytopenic purpura caused by a novel compound heterozygous mutation of the ADAMTS13 gene.Characterization of conformation-sensitive antibodies to ADAMTS13, the von Willebrand cleavage proteaseForce-induced cleavage of single VWFA1A2A3 tridomains by ADAMTS-13.Amino acid residues Arg(659), Arg(660), and Tyr(661) in the spacer domain of ADAMTS13 are critical for cleavage of von Willebrand factor.Thrombospondin 1 requires von Willebrand factor to modulate arterial thrombosis in miceExosite interactions contribute to tension-induced cleavage of von Willebrand factor by the antithrombotic ADAMTS13 metalloproteaseThe role of the ADAMTS13 cysteine-rich domain in VWF binding and proteolysis.Recombinant CUB-1 domain polypeptide inhibits the cleavage of ULVWF strings by ADAMTS13 under flow conditions.The cooperative activity between the carboxyl-terminal TSP1 repeats and the CUB domains of ADAMTS13 is crucial for recognition of von Willebrand factor under flow.A novel binding site for ADAMTS13 constitutively exposed on the surface of globular VWF.Rearranging exosites in noncatalytic domains can redirect the substrate specificity of ADAMTS proteases.Extensive contacts between ADAMTS13 exosites and von Willebrand factor domain A2 contribute to substrate specificity.The proximal carboxyl-terminal domains of ADAMTS13 determine substrate specificity and are all required for cleavage of von Willebrand factor.Emerging Roles of ADAMTSs in Angiogenesis and Cancer.Multi-step binding of ADAMTS-13 to von Willebrand factor.ADAMTS13 bound to endothelial cells exhibits enhanced cleavage of von Willebrand factor.The ADAMTS13 metalloprotease domain: roles of subsites in enzyme activity and specificity.
P2860
Q24301310-5AB0A975-EB16-4B5C-9F55-25DF9F36650FQ24338203-928CA864-E47C-4AAF-9384-94ECEA55749CQ24655131-587F6C21-8B46-483C-9AE7-9EB2AABF39B5Q24656680-4F21C029-CC63-421A-B8E9-59BACF789104Q24658043-AE61015F-0FCF-46FB-BAD1-F760E66D5E5BQ26827966-217A79A0-B3CB-4825-85AB-CBAF740CCE66Q28083264-C5BF577E-4DD3-4A53-9641-C277C7B5E17EQ29568910-2193969C-2AF1-47E5-BDC3-EE70DD81BD5BQ30364288-43672A9B-6FCE-4481-906D-8DFDBA86CDA0Q30437176-AA0BEF0B-C02E-4D52-A466-162DC1ED68B3Q33231921-0302294E-41C1-42EF-9F53-BAE9CC2736ACQ33278139-C973F1B1-5AE6-4C45-A50F-3A22DC5261B1Q33369765-8D11A35E-3A1E-4C72-A480-CC764AD8AB89Q33371177-7FEB68FA-C161-4204-AA7B-F23CE2504C35Q33372115-9CEF7F14-8EC1-4301-B9C9-ED8C30522DE3Q33374872-F51390F1-4B4A-4669-B87A-60E9FD093295Q33378594-C6C8CACC-C3A8-4244-B2EF-194C044276C8Q33382110-40AEBFC9-74F8-4A16-868C-7632FF77DB42Q33382570-789DFF4E-6946-4539-9452-E3F98459F1A4Q33382602-51B6BAAF-0B16-467B-8953-D1E1D059A343Q33398887-6378BED2-5C59-4869-92D9-96BB773A87BEQ33403769-CFC102A9-6A94-485D-9DAA-D8E49895ADA1Q33419359-0FF24E22-46C5-4866-A126-EB37F7BC9B35Q33425140-1FE704B5-C247-4A4F-AEEC-42279008B609Q33490606-B09DC3B8-2B5A-4DA0-8DAF-BD4E67172C70Q33597546-C16009DD-1970-489C-8BBA-9062E3AAC7CFQ33747303-D3AC83B4-4A43-4C39-BA35-62B2AB8A6995Q35040540-334346A0-F1CD-47AD-B7A6-18D7BE6DF333Q35193294-C4EAE853-8156-4501-AA02-3F85F53063D9Q35197446-D08281D6-E218-4466-BAFE-E4308A7EDF47Q35848128-11269388-B09D-4C61-BEC0-693B813C65BDQ35990745-1DA5588B-DF5E-4CA0-988C-A1794222B44BQ36109433-E85BA77B-A5F3-4888-947F-3ACC6508780EQ36137447-33C9EFF6-CFBC-4FD5-A196-8054CF1B14D8Q36843699-E709415B-6F17-4735-8765-0F5882EC4D25Q36959300-294D10C1-B493-44E7-AA8C-494F7E22D942Q37017089-7E4CBAAE-A426-4AB1-AB78-2807EC0A4B52Q37393329-F4092F6C-BEB2-486B-B1EC-C730D13B7528Q37431399-DF6F428C-570B-45B5-B197-6D515E6596A0Q39677665-2CA2E2B4-7BB2-47B7-8CA6-C813FD5DCC9A
P2860
description
2005 nî lūn-bûn
@nan
2005 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Binding of ADAMTS13 to von Willebrand factor
@ast
Binding of ADAMTS13 to von Willebrand factor
@en
Binding of ADAMTS13 to von Willebrand factor
@nl
type
label
Binding of ADAMTS13 to von Willebrand factor
@ast
Binding of ADAMTS13 to von Willebrand factor
@en
Binding of ADAMTS13 to von Willebrand factor
@nl
prefLabel
Binding of ADAMTS13 to von Willebrand factor
@ast
Binding of ADAMTS13 to von Willebrand factor
@en
Binding of ADAMTS13 to von Willebrand factor
@nl
P2860
P356
P1476
Binding of ADAMTS13 to von Willebrand factor
@en
P2093
Elaine M Majerus
Patricia J Anderson
P2860
P304
P356
10.1074/JBC.M502529200
P407
P577
2005-06-10T00:00:00Z