Cyclin-dependent kinase 16/PCTAIRE kinase 1 is activated by cyclin Y and is essential for spermatogenesis
about
Analysis of substrate specificity and cyclin Y binding of PCTAIRE-1 kinasePhosphorylation of cyclin Y by CDK14 induces its ubiquitination and degradationThe emerging roles and therapeutic potential of cyclin-dependent kinase 11 (CDK11) in human cancerTargeting cyclin-dependent kinases in human cancers: from small molecules to Peptide inhibitorsThe function and molecular mechnism of cyclin Y proteinCCNYL1, but Not CCNY, Cooperates with CDK16 to Regulate Spermatogenesis in MousePCTAIRE1 phosphorylates p27 and regulates mitosis in cancer cells.Cyclin Y inhibits plasticity-induced AMPA receptor exocytosis and LTP.Cyclin-dependent kinasesUp-regulation of CDK16 by multiple mechanisms in hepatocellular carcinoma promotes tumor progression.Identification of potential synthetic lethal genes to p53 using a computational biology approachTargeting cell cycle regulators in hematologic malignancies.Cyclin Y Is Involved in the Regulation of Adipogenesis and Lipid Production.Functional significance of the sex chromosomes during spermatogenesis.Cyclin Y phosphorylation- and 14-3-3-binding-dependent activation of PCTAIRE-1/CDK16.Structure and inhibitor specificity of the PCTAIRE-family kinase CDK16.Upregulated CDK16 Expression in Serous Epithelial Ovarian Cancer Cells.Orphan kinases turn eccentric: a new class of cyclin Y-activated, membrane-targeted CDKsAn investigation of excess residual cytoplasm in human spermatozoa and its distinction from the cytoplasmic dropletPIAS1 is a determinant of poor survival and acts as a positive feedback regulator of AR signaling through enhanced AR stabilization in prostate cancer.Lipid Nanoparticle-mediated siRNA Transfer Against PCTAIRE1/PCTK1/Cdk16 Inhibits In Vivo Cancer Growth.Mitotic phosphorylation of eukaryotic initiation factor 4G1 (eIF4G1) at Ser1232 by Cdk1:cyclin B inhibits eIF4A helicase complex binding with RNA.The control of male fertility by spermatid-specific factors: searching for contraceptive targets from spermatozoon's head to tail.Structural characterization of the cyclin-dependent protein kinase family.Timing in the Testis.Targeting Cyclin-Dependent Kinases in Ovarian Cancer.Human CDK18 promotes replication stress signaling and genome stability.PCTAIRE1-knockdown sensitizes cancer cells to TNF family cytokines.Pctaire1/Cdk16 promotes skeletal myogenesis by inducing myoblast migration and fusion.PCTAIRE kinase 3/cyclin-dependent kinase 18 is activated through association with cyclin A and/or phosphorylation by protein kinase A."Bam," a novel glucocorticoid-induced BH3-only transcript from the BCL2L11/Bim locus, does not appear to be translated.PCTK1 regulates integrin-dependent spindle orientation via protein kinase A regulatory subunit KAP0 and myosin X.Structures of the CDK12/CycK complex with AMP-PNP reveal a flexible C-terminal kinase extension important for ATP binding.CDK14 expression is down-regulated by cigarette smoke in vivo and in vitro.PCTAIRE1 regulates p27 stability, apoptosis and tumor growth in malignant melanoma.CDK16 Phosphorylates and Degrades p53 to Promote Radioresistance and Predicts Prognosis in Lung Cancer.Phospholipase Cβ1 regulates proliferation of neuronal cells.Cyclin Y Modulates the Proliferation, Invasion, and Metastasis of Hepatocellular Carcinoma Cells.Structural insights into the functional diversity of the CDK-cyclin family
P2860
Q24293247-8BF62FB4-822D-40A0-B11B-B2DE59C92005Q24296952-A95B87EA-04A4-41D9-9973-1F6BEE108CF0Q26751387-816EF2AF-41D2-495A-8D0A-C616B90300EBQ26827580-2C4590B2-4F34-4695-BC0C-88C27CBD195BQ27025081-23B97999-629A-456F-8565-3CEB01A60844Q27310333-81427FC1-1ED3-45BF-9004-381253B9D85EQ30593254-047280FE-E579-457A-BFB0-F632C232EB01Q30659336-78A8AA58-CA8A-4D24-9108-A39D42CD0757Q33900533-350E6D25-F391-4EAB-A1DD-37EB513AD106Q33913172-65AEC639-20B0-41D5-8168-BCA83FB4CC8CQ34985284-35A83A78-8B5B-4912-80E1-8F94AE691B88Q35334436-43E5AAD8-BF70-4B42-8B9D-E8888AE98544Q35688145-AC473E8C-A38F-4B42-9232-FD08761E16ACQ35878326-6A10BF47-BE42-43AD-8A5F-820DE0B7AF1BQ36184696-190674C5-6188-41DB-9E2E-F9DE454717B1Q36241608-E9028168-315C-42A3-BCCA-5E945F4C25E7Q36274556-BB60498E-0A49-47E7-989C-E93F6588FEC8Q36392120-4F5EC552-9F18-41BD-8C7E-FDCEA1E91BADQ36552632-AF8C4A98-E0F5-421C-A1D6-6CDF12E2EA57Q36896806-DD6D1219-EE64-44F0-B71C-9EB39D1BB01BQ37254642-7781046C-24B3-402A-8FB6-9FD4E2CEC888Q37546968-B278FD88-4C74-47CE-9B5F-F3BBF1674A31Q37603295-6537F19F-94FC-456A-ADE4-73506D99181EQ38122234-E7B80FC0-FE54-4C06-9F71-CD490496A76AQ38666224-1E096AA0-3EB8-4C41-92D0-3924255C5DBBQ38730812-A789E774-C986-402C-A708-5C3B02363714Q38759647-4833C6F2-5BB5-41AE-AD9E-BF6568F393E5Q38897501-5CE13F02-5A63-4FCA-A82F-340E0D37424EQ38984521-979137BD-026D-498C-ACEF-9D1228F0BB9EQ38994705-D5B11FD1-54D4-4D33-BAE2-5CCAE5A937D8Q39319809-6DA773A3-A0FF-478E-962B-969AA31CEABDQ41991085-3E71BB63-FE16-41CB-971B-4F35F16C60B4Q41994738-1F406710-CF58-4E0E-8D64-D814727F3920Q42574675-CEDFBF82-8CB4-4CE0-80C1-0275968292D4Q43083384-429A7BFE-12B0-4645-AC49-EC607CFBC97EQ49166463-2A848922-B1F4-4804-8D4B-088D459D7532Q52699545-1D905C28-B9E1-4329-9EB4-BCB0A971D11EQ52725502-D0B21833-2041-4974-B6C9-0F723D36933DQ58762403-0FF3E480-4B27-4258-9735-136CB6AD4FC4
P2860
Cyclin-dependent kinase 16/PCTAIRE kinase 1 is activated by cyclin Y and is essential for spermatogenesis
description
2012 nî lūn-bûn
@nan
2012 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Cyclin-dependent kinase 16/PCT ...... essential for spermatogenesis
@ast
Cyclin-dependent kinase 16/PCT ...... essential for spermatogenesis
@en
Cyclin-dependent kinase 16/PCT ...... essential for spermatogenesis
@en-gb
Cyclin-dependent kinase 16/PCT ...... essential for spermatogenesis
@nl
type
label
Cyclin-dependent kinase 16/PCT ...... essential for spermatogenesis
@ast
Cyclin-dependent kinase 16/PCT ...... essential for spermatogenesis
@en
Cyclin-dependent kinase 16/PCT ...... essential for spermatogenesis
@en-gb
Cyclin-dependent kinase 16/PCT ...... essential for spermatogenesis
@nl
prefLabel
Cyclin-dependent kinase 16/PCT ...... essential for spermatogenesis
@ast
Cyclin-dependent kinase 16/PCT ...... essential for spermatogenesis
@en
Cyclin-dependent kinase 16/PCT ...... essential for spermatogenesis
@en-gb
Cyclin-dependent kinase 16/PCT ...... essential for spermatogenesis
@nl
P2093
P2860
P921
P3181
P356
P1476
Cyclin-dependent kinase 16/PCT ...... essential for spermatogenesis
@en
P2093
Kristian Pfaller
Lauri J Pelliniemi
Michael Boesl
Petra Mikolcevic
Reinhard Sigl
Stephan Geley
Veronika Rauch
P2860
P304
P3181
P356
10.1128/MCB.06261-11
P407
P577
2011-12-19T00:00:00Z