Nucleotide and deduced amino acid sequence of a human cDNA (NQO2) corresponding to a second member of the NAD(P)H:quinone oxidoreductase gene family. Extensive polymorphism at the NQO2 gene locus on chromosome 6
about
Unexpected genetic and structural relationships of a long-forgotten flavoenzyme to NAD(P)H:quinone reductase (DT-diaphorase)Update of the NAD(P)H:quinone oxidoreductase (NQO) gene familyMechanism-Based Inhibition of Quinone Reductase 2 (NQO2): Selectivity for NQO2 over NQO1 and Structural Basis for Flavoprotein InhibitionQuinone reductase inhibitors block SAPK/JNK and NFkappaB pathways and potentiate apoptosisInduction of DT-diaphorase by 1,2-dithiole-3-thione and increase of antitumour activity of bioreductive agentsAntagonism between members of the CNC-bZIP family and the immediate-early protein IE2 of human cytomegalovirus.Relationships between metabolic and non-metabolic susceptibility factors in benzene toxicity.The NADH:ubiquinone oxidoreductase (complex I) of respiratory chains.Quinone reductases multitasking in the metabolic world.Presence of a heterozygous substitution and its relationship to DT-diaphorase activity.A two-domain structure for the two subunits of NAD(P)H:quinone acceptor oxidoreductaseMouse liver NAD(P)H:quinone acceptor oxidoreductase: protein sequence analysis by tandem mass spectrometry, cDNA cloning, expression in Escherichia coli, and enzyme activity analysis.Induction of DT-diaphorase by 1,2-dithiole-3-thiones in human tumour and normal cells and effect on anti-tumour activity of bioreductive agents.Fortilin potentiates the peroxidase activity of Peroxiredoxin-1 and protects against alcohol-induced liver damage in mice.DT-diaphorase and cytochrome B5 reductase in human lung and breast tumoursEnhanced cytotoxicity of mitomycin C in human tumour cells with inducers of DT-diaphorase.A unique cytosolic activity related but distinct from NQO1 catalyses metabolic activation of mitomycin CDietary induction of NQO1 increases the antitumour activity of mitomycin C in human colon tumours in vivo.Resveratrol: Biological and pharmaceutical properties as anticancer molecule.Quinone reductase 2 is a catechol quinone reductaseNAD(P)H: quinone oxidoreductase 1 and NRH:quinone oxidoreductase 2 polymorphisms in papillary thyroid microcarcinoma: correlation with phenotype.Evidence for NQO2-mediated reduction of the carcinogenic estrogen ortho-quinonesNAD(P)H: quinone oxidoreductase 1 and its potential protective role in cardiovascular diseases and related conditions.Role of Drug Metabolism in the Cytotoxicity and Clinical Efficacy of Anthracyclines.Indolequinone inhibitors of NRH:quinone oxidoreductase 2. Characterization of the mechanism of inhibition in both cell-free and cellular systems.Enzymology of bioreductive drug activation.Functions of NQO1 in Cellular Protection and CoQ10 Metabolism and its Potential Role as a Redox Sensitive Molecular Switch.The molecular epidemiology of lung cancer.A Model for NAD(P)H:Quinoneoxidoreductase 1 (NQO1) Targeted Individualized Cancer Chemotherapy.Quinone oxidoreductase message levels are differentially regulated in parasitic and non-parasitic plants exposed to allelopathic quinones.In vivo role of NAD(P)H:quinone oxidoreductase 1 (NQO1) in the regulation of intracellular redox state and accumulation of abdominal adipose tissue.Disruption of dihydronicotinamide riboside:quinone oxidoreductase 2 (NQO2) leads to myeloid hyperplasia of bone marrow and decreased sensitivity to menadione toxicity.Organs from mice deleted for NRH:quinone oxidoreductase 2 are deprived of the melatonin binding site MT3.Evidence for NQO1 and NQO2 catalyzed reduction of ortho- and para-quinone methides.Reduction and Scavenging of Chemically Reactive Drug Metabolites by NAD(P)H:Quinone Oxidoreductase 1 and NRH:Quinone Oxidoreductase 2 and Variability in Hepatic Concentrations.The ontogeny and population variability of human hepatic dihydronicotinamide riboside:quinone oxidoreductase (NQO2).Good genes, oxidative stress and condition-dependent sexual signals.
P2860
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P2860
Nucleotide and deduced amino acid sequence of a human cDNA (NQO2) corresponding to a second member of the NAD(P)H:quinone oxidoreductase gene family. Extensive polymorphism at the NQO2 gene locus on chromosome 6
description
1990 nî lūn-bûn
@nan
1990 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1990 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
name
Nucleotide and deduced amino a ...... QO2 gene locus on chromosome 6
@ast
Nucleotide and deduced amino a ...... QO2 gene locus on chromosome 6
@en
Nucleotide and deduced amino a ...... QO2 gene locus on chromosome 6
@en-gb
Nucleotide and deduced amino a ...... QO2 gene locus on chromosome 6
@nl
type
label
Nucleotide and deduced amino a ...... QO2 gene locus on chromosome 6
@ast
Nucleotide and deduced amino a ...... QO2 gene locus on chromosome 6
@en
Nucleotide and deduced amino a ...... QO2 gene locus on chromosome 6
@en-gb
Nucleotide and deduced amino a ...... QO2 gene locus on chromosome 6
@nl
prefLabel
Nucleotide and deduced amino a ...... QO2 gene locus on chromosome 6
@ast
Nucleotide and deduced amino a ...... QO2 gene locus on chromosome 6
@en
Nucleotide and deduced amino a ...... QO2 gene locus on chromosome 6
@en-gb
Nucleotide and deduced amino a ...... QO2 gene locus on chromosome 6
@nl
P2093
P356
P1433
P1476
Nucleotide and deduced amino a ...... QO2 gene locus on chromosome 6
@en
P2093
A K Jaiswal
O W McBride
P304
P356
10.1021/BI00459A034
P407
P577
1990-02-20T00:00:00Z