Adenovirus-mediated overexpression of p14(ARF) induces p53 and Bax-independent apoptosis
about
EAPP, a novel E2F binding protein that modulates E2F-dependent transcriptionActivation of p53 by MEG3 non-coding RNAp14ARF induces G2 cell cycle arrest in p53- and p21-deficient cells by down-regulating p34cdc2 kinase activityTargeting of C-terminal binding protein (CtBP) by ARF results in p53-independent apoptosis.Induction of cell death by the BH3-only Bcl-2 homolog Nbk/Bik is mediated by an entirely Bax-dependent mitochondrial pathwayIn B-CLL, the codon 72 polymorphic variants of p53 are not related to drug resistance and disease prognosisDivorcing ARF and p53: an unsettled caseTumor suppressor ARF inhibits HER-2/neu-mediated oncogenic growthDNA damage-induced expression of p53 suppresses mitotic checkpoint kinase hMps1: the lack of this suppression in p53MUT cells contributes to apoptosisTIP30 regulates apoptosis-related genes in its apoptotic signal transduction pathwayInvolvement of GLTSCR2 in the DNA Damage Response.Loss of p19(Arf) facilitates the angiogenic switch and tumor initiation in a multi-stage cancer model via p53-dependent and independent mechanisms.Multigene analysis of Rb pathway and apoptosis control in esophageal squamous cell carcinoma identifies patients with good prognosis.Paclitaxel-induced apoptosis in BJAB cells proceeds via a death receptor-independent, caspases-3/-8-driven mitochondrial amplification loop.Combined p53/Bax mutation results in extremely poor prognosis in gastric carcinoma with low microsatellite instability.Mutation of p53 and consecutive selective drug resistance in B-CLL occurs as a consequence of prior DNA-damaging chemotherapy.Tumor necrosis factor alpha sensitizes malignant cells to chemotherapeutic drugs via the mitochondrial apoptosis pathway independently of caspase-8 and NF-kappaB.Arsenic trioxide triggers a regulated form of caspase-independent necrotic cell death via the mitochondrial death pathway.Arsenic trioxide induces regulated, death receptor-independent cell death through a Bcl-2-controlled pathway.Equivalent effect of DNA damage-induced apoptotic cell death or long-term cell cycle arrest on colon carcinoma cell proliferation and tumour growth.Induction of p21CIP/WAF-1 and G2 arrest by ionizing irradiation impedes caspase-3-mediated apoptosis in human carcinoma cells.Genetic dissection of apoptosis and cell cycle control in response of colorectal cancer treated with preoperative radiochemotherapy.Bak functionally complements for loss of Bax during p14ARF-induced mitochondrial apoptosis in human cancer cells.Mcl-1 determines the Bax dependency of Nbk/Bik-induced apoptosis.Cooperative effect of p21Cip1/WAF-1 and 14-3-3sigma on cell cycle arrest and apoptosis induction by p14ARF.Endogenous Bak inhibitors Mcl-1 and Bcl-xL: differential impact on TRAIL resistance in Bax-deficient carcinoma.Fusaric Acid immunotoxicity and MAPK activation in normal peripheral blood mononuclear cells and Thp-1 cellsDifferential regulation of the proapoptotic multidomain protein Bak by p53 and p73 at the promoter levelp300 regulates p53-dependent apoptosis after DNA damage in colorectal cancer cells by modulation of PUMA/p21 levels.Dynamics of ARF regulation that control senescence and cancer.p14(ARF)-induced apoptosis in p53 protein-deficient cells is mediated by BH3-only protein-independent derepression of Bak protein through down-regulation of Mcl-1 and Bcl-xL proteins.PIWIL4 regulates cervical cancer cell line growth and is involved in down-regulating the expression of p14ARF and p53.ARF mutation accelerates pituitary tumor development in Rb+/- mice.p14ARF induces apoptosis via an entirely caspase-3-dependent mitochondrial amplification loop.Modelling the onset of senescence at the G1/S cell cycle checkpoint.Selective requirement of H2B N-Terminal tail for p14ARF-induced chromatin silencing.Gene therapy progress and prospects: cancer gene therapy using tumour suppressor genes.Mitochondrial p32 is a critical mediator of ARF-induced apoptosisP14ARF inhibits human glioblastoma-induced angiogenesis by upregulating the expression of TIMP3.MicroRNA-149 inhibits proliferation and cell cycle progression through the targeting of ZBTB2 in human gastric cancer.
P2860
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P2860
Adenovirus-mediated overexpression of p14(ARF) induces p53 and Bax-independent apoptosis
description
2002 nî lūn-bûn
@nan
2002 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Adenovirus-mediated overexpression of p14(ARF) induces p53 and Bax-independent apoptosis
@ast
Adenovirus-mediated overexpression of p14(ARF) induces p53 and Bax-independent apoptosis
@en
Adenovirus-mediated overexpression of p14(ARF) induces p53 and Bax-independent apoptosis
@en-gb
Adenovirus-mediated overexpression of p14(ARF) induces p53 and Bax-independent apoptosis
@nl
type
label
Adenovirus-mediated overexpression of p14(ARF) induces p53 and Bax-independent apoptosis
@ast
Adenovirus-mediated overexpression of p14(ARF) induces p53 and Bax-independent apoptosis
@en
Adenovirus-mediated overexpression of p14(ARF) induces p53 and Bax-independent apoptosis
@en-gb
Adenovirus-mediated overexpression of p14(ARF) induces p53 and Bax-independent apoptosis
@nl
prefLabel
Adenovirus-mediated overexpression of p14(ARF) induces p53 and Bax-independent apoptosis
@ast
Adenovirus-mediated overexpression of p14(ARF) induces p53 and Bax-independent apoptosis
@en
Adenovirus-mediated overexpression of p14(ARF) induces p53 and Bax-independent apoptosis
@en-gb
Adenovirus-mediated overexpression of p14(ARF) induces p53 and Bax-independent apoptosis
@nl
P2093
P2860
P921
P356
P1433
P1476
Adenovirus-mediated overexpression of p14(ARF) induces p53 and Bax-independent apoptosis
@en
P2093
Bernd Dörken
Bernhard Gillissen
Dilek Güner
Jana Wendt
Lilian Stärck
Peter T Daniel
Philipp G Hemmati
P2860
P2888
P304
P356
10.1038/SJ.ONC.1205458
P407
P577
2002-05-09T00:00:00Z
P5875
P6179
1053607969