Novel human homologues of p47phox and p67phox participate in activation of superoxide-producing NADPH oxidases
about
Activation of the superoxide-producing phagocyte NADPH oxidase requires co-operation between the tandem SH3 domains of p47phox in recognition of a polyproline type II helix and an adjacent alpha-helix of p22phoxNovel p47(phox)-related organizers regulate localized NADPH oxidase 1 (Nox1) activityPhosphorylation of Noxo1 at threonine 341 regulates its interaction with Noxa1 and the superoxide-producing activity of Nox1Direct interaction between Tks proteins and the N-terminal proline-rich region (PRR) of NoxA1 mediates Nox1-dependent ROS generationInvolvement of Rac1 in activation of multicomponent Nox1- and Nox3-based NADPH oxidasesInhibitory action of NoxA1 on dual oxidase activity in airway cellsDual oxidasesCritical roles for p22phox in the structural maturation and subcellular targeting of Nox3Natural compounds as modulators of NADPH oxidasesStudy designs to investigate Nox1 acceleration of neoplastic progression in immortalized human epithelial cells by selection of differentiation resistant cellsBiochemistry, physiology, and pathophysiology of NADPH oxidases in the cardiovascular systemDetection of superoxide anion and hydrogen peroxide production by cellular NADPH oxidasesNADPH oxidases in lung health and diseasePhosphorylation of p22phox on threonine 147 enhances NADPH oxidase activity by promoting p47phox bindingMutation of the Cyba gene encoding p22phox causes vestibular and immune defects in miceStructure, regulation and evolution of Nox-family NADPH oxidases that produce reactive oxygen speciesIdentification of a novel partner of duox: EFP1, a thioredoxin-related proteinMutational analysis reveals distinct features of the Nox4-p22 phox complexReactive oxygen species in inflammation and tissue injuryNovel role of NOX in supporting aerobic glycolysis in cancer cells with mitochondrial dysfunction and as a potential target for cancer therapyPeroxiredoxin 6 (Prdx6) supports NADPH oxidase1 (Nox1)-based superoxide generation and cell migration.Regulation of NOXO1 activity through reversible interactions with p22 and NOXA1.A molecular mechanism for autoinhibition of the tandem SH3 domains of p47phox, the regulatory subunit of the phagocyte NADPH oxidase.Angiotensin II induces a region-specific hyperplasia of the ascending aorta through regulation of inhibitor of differentiation 3.Traumatic noise activates Rho-family GTPases through transient cellular energy depletionTargeting and regulation of reactive oxygen species generation by Nox family NADPH oxidases.Rac/Rho pathway regulates actin depolymerization induced by aminoglycoside antibiotics.The NADPH oxidase Nox3 constitutively produces superoxide in a p22phox-dependent manner: its regulation by oxidase organizers and activators.Molecular evolution of the reactive oxygen-generating NADPH oxidase (Nox/Duox) family of enzymesMolecular evolution of Phox-related regulatory subunits for NADPH oxidase enzymes.NADPH oxidases: a perspective on reactive oxygen species production in tumor biologyEmerging evidence for the importance of phosphorylation in the regulation of NADPH oxidases.Nox activator 1: a potential target for modulation of vascular reactive oxygen species in atherosclerotic arteriesExpression of NADPH oxidase homologues and accessory genes in human cancer cell lines, tumours and adjacent normal tissuesT3SS effector VopL inhibits the host ROS response, promoting the intracellular survival of Vibrio parahaemolyticus.Hydrogen sulfide regulates homocysteine-mediated glomerulosclerosisEpidermal growth factor stimulates nuclear factor-κB activation and heme oxygenase-1 expression via c-Src, NADPH oxidase, PI3K, and Akt in human colon cancer cellsA conserved region between the TPR and activation domains of p67phox participates in activation of the phagocyte NADPH oxidase.Comparative pharmacology of chemically distinct NADPH oxidase inhibitors.Mechanism of Ca2+ activation of the NADPH oxidase 5 (NOX5).
P2860
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P2860
Novel human homologues of p47phox and p67phox participate in activation of superoxide-producing NADPH oxidases
description
2003 nî lūn-bûn
@nan
2003 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Novel human homologues of p47p ...... oxide-producing NADPH oxidases
@ast
Novel human homologues of p47p ...... oxide-producing NADPH oxidases
@en
Novel human homologues of p47p ...... oxide-producing NADPH oxidases
@en-gb
Novel human homologues of p47p ...... oxide-producing NADPH oxidases
@nl
type
label
Novel human homologues of p47p ...... oxide-producing NADPH oxidases
@ast
Novel human homologues of p47p ...... oxide-producing NADPH oxidases
@en
Novel human homologues of p47p ...... oxide-producing NADPH oxidases
@en-gb
Novel human homologues of p47p ...... oxide-producing NADPH oxidases
@nl
prefLabel
Novel human homologues of p47p ...... oxide-producing NADPH oxidases
@ast
Novel human homologues of p47p ...... oxide-producing NADPH oxidases
@en
Novel human homologues of p47p ...... oxide-producing NADPH oxidases
@en-gb
Novel human homologues of p47p ...... oxide-producing NADPH oxidases
@nl
P2093
P356
P1476
Novel human homologues of p47p ...... oxide-producing NADPH oxidases
@en
P2093
Hideki Sumimoto
Hiroyuki Nunoi
Keiichiro Kami
Masahiko Taura
Motoyuki Kohjima
Noriko Ueno
Ryu Takeya
Tomoko Izaki
P304
P356
10.1074/JBC.M212856200
P407
P577
2003-07-04T00:00:00Z