STAT3 protein up-regulates Gα-interacting vesicle-associated protein (GIV)/Girdin expression, and GIV enhances STAT3 activation in a positive feedback loop during wound healing and tumor invasion/metastasis
about
Heterotrimeric G proteins as emerging targets for network based therapy in cancer: End of a long futile campaign striking heads of a HydraRANK-mediated signaling network and cancer metastasis.Inhibition of Girdin enhances chemosensitivity of colorectal cancer cells to oxaliplatin.Expression of Girdin in primary hepatocellular carcinoma and its effect on cell proliferation and invasion.Multimodular biosensors reveal a novel platform for activation of G proteins by growth factor receptors.GIV/Girdin transmits signals from multiple receptors by triggering trimeric G protein activation.Therapeutic effects of cell-permeant peptides that activate G proteins downstream of growth factors.Integrins activate trimeric G proteins via the nonreceptor protein GIV/GirdinInterleukin-17 promotes angiogenesis by stimulating VEGF production of cancer cells via the STAT3/GIV signaling pathway in non-small-cell lung cancer.Activation of G proteins by GIV-GEF is a pivot point for insulin resistance and sensitivity.Constitutive activation of STAT3 in breast cancer cells: A review.Girdin expression in cervical carcinoma and its role in the malignant properties of HeLa cells.GIV/Girdin (Gα-interacting, Vesicle-associated Protein/Girdin) Creates a Positive Feedback Loop That Potentiates Outside-in Integrin Signaling in Cancer Cells.Clinical implications of Girdin and PI3K protein expression in breast cancer.Girdin (GIV) Expression as a Prognostic Marker of Recurrence in Mismatch Repair-Proficient Stage II Colon CancerThe untapped potential of tyrosine-based G protein signaling.Heterotrimeric G protein signaling via GIV/Girdin: Breaking the rules of engagement, space, and time.Discs large homolog 5 decreases formation and function of invadopodia in human hepatocellular carcinoma via Girdin and Tks5.GIV/Girdin is a central hub for profibrogenic signalling networks during liver fibrosis.The Gαi-GIV binding interface is a druggable protein-protein interactionG protein coupled growth factor receptor tyrosine kinase: no longer an oxymoron.Prognostic impact of total and tyrosine phosphorylated GIV/Girdin in breast cancers.Biochemical, Biophysical and Cellular Techniques to Study the Guanine Nucleotide Exchange Factor, GIV/Girdin.Girdin protein: A potential metastasis predictor associated with prognosis in lung cancer.Gankyrin promotes tumor growth and metastasis through activation of IL-6/STAT3 signaling in human cholangiocarcinoma.
P2860
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P2860
STAT3 protein up-regulates Gα-interacting vesicle-associated protein (GIV)/Girdin expression, and GIV enhances STAT3 activation in a positive feedback loop during wound healing and tumor invasion/metastasis
description
2012 nî lūn-bûn
@nan
2012 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
STAT3 protein up-regulates Gα- ...... and tumor invasion/metastasis
@ast
STAT3 protein up-regulates Gα- ...... and tumor invasion/metastasis
@en
STAT3 protein up-regulates Gα- ...... and tumor invasion/metastasis
@en-gb
STAT3 protein up-regulates Gα- ...... and tumor invasion/metastasis
@nl
type
label
STAT3 protein up-regulates Gα- ...... and tumor invasion/metastasis
@ast
STAT3 protein up-regulates Gα- ...... and tumor invasion/metastasis
@en
STAT3 protein up-regulates Gα- ...... and tumor invasion/metastasis
@en-gb
STAT3 protein up-regulates Gα- ...... and tumor invasion/metastasis
@nl
prefLabel
STAT3 protein up-regulates Gα- ...... and tumor invasion/metastasis
@ast
STAT3 protein up-regulates Gα- ...... and tumor invasion/metastasis
@en
STAT3 protein up-regulates Gα- ...... and tumor invasion/metastasis
@en-gb
STAT3 protein up-regulates Gα- ...... and tumor invasion/metastasis
@nl
P2093
P2860
P356
P1476
STAT3 protein up-regulates Gα- ...... and tumor invasion/metastasis
@en
P2093
Andrew Ong
Dimple Notani
Michael Lam
Pradipta Ghosh
Yash Mittal
Ying Dunkel
P2860
P304
P356
10.1074/JBC.M112.390781
P407
P577
2012-12-07T00:00:00Z