Constitutive c-jun N-terminal kinase activity in acute myeloid leukemia derives from Flt3 and affects survival and proliferation
about
FLT3 D835/I836 mutations are associated with poor disease-free survival and a distinct gene-expression signature among younger adults with de novo cytogenetically normal acute myeloid leukemia lacking FLT3 internal tandem duplications.Regulation of Stat5 by FAK and PAK1 in Oncogenic FLT3- and KIT-Driven LeukemogenesisRho kinase regulates the survival and transformation of cells bearing oncogenic forms of KIT, FLT3, and BCR-ABL.TAK1 is required for the survival of hematopoietic cells and hepatocytes in mice.Lineage-specific and single-cell chromatin accessibility charts human hematopoiesis and leukemia evolution.MAPK signaling pathways in the regulation of hematopoiesis.The protein tyrosine phosphatase, Shp2, positively contributes to FLT3-ITD-induced hematopoietic progenitor hyperproliferation and malignant disease in vivo.A noncanonical Flt3ITD/NF-κB signaling pathway represses DAPK1 in acute myeloid leukemia.NPM-RAR binding to TRADD selectively inhibits caspase activation, while allowing activation of NFκB and JNK.Genome-wide genotype-based risk model for survival in acute myeloid leukaemia patients with normal karyotype.A single amino acid substitution confers B-cell clonogenic activity to the HIV-1 matrix protein p17.Consecutive epigenetically-active agent combinations act in ID1-RUNX3-TET2 and HOXA pathways for Flt3ITD+ve AML.CBL mutation-related patterns of phosphorylation and sensitivity to tyrosine kinase inhibitors.
P2860
Q27851415-90C3DA05-E125-4769-8D47-ACF74DD71BBBQ35235210-241F47E5-7D83-45F8-A098-C04FD3C59589Q35513750-D5FB1687-517B-4D8C-9394-53AA657B201EQ36742272-689142B3-6252-4DD2-AF34-E6CDF2BB807FQ37297694-4299FA5F-39B2-479E-A20C-4BA4782F0545Q37508518-E6071351-DC5B-4815-B4BC-580883A9037EQ37564987-C713577E-EB9B-4295-8F1C-092AD8922513Q37569994-E757B443-559A-495F-BBAB-8F20A0F8E506Q38268232-5F58D78B-65F7-41D1-9537-7C893ED86D96Q38445540-8B9F0370-4A75-41C4-89F4-DF39821C04C7Q38659232-31CCAE36-C02A-438F-8E35-9105875CEB95Q49787877-B7E4C59A-D2BF-4791-9541-021F5660F61DQ54329349-3C372DF4-3E8C-4E98-AE66-1E9ECE1B591B
P2860
Constitutive c-jun N-terminal kinase activity in acute myeloid leukemia derives from Flt3 and affects survival and proliferation
description
2006 nî lūn-bûn
@nan
2006 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Constitutive c-jun N-terminal ...... cts survival and proliferation
@ast
Constitutive c-jun N-terminal ...... cts survival and proliferation
@en
Constitutive c-jun N-terminal ...... cts survival and proliferation
@en-gb
Constitutive c-jun N-terminal ...... cts survival and proliferation
@nl
type
label
Constitutive c-jun N-terminal ...... cts survival and proliferation
@ast
Constitutive c-jun N-terminal ...... cts survival and proliferation
@en
Constitutive c-jun N-terminal ...... cts survival and proliferation
@en-gb
Constitutive c-jun N-terminal ...... cts survival and proliferation
@nl
prefLabel
Constitutive c-jun N-terminal ...... cts survival and proliferation
@ast
Constitutive c-jun N-terminal ...... cts survival and proliferation
@en
Constitutive c-jun N-terminal ...... cts survival and proliferation
@en-gb
Constitutive c-jun N-terminal ...... cts survival and proliferation
@nl
P2093
P1476
Constitutive c-jun N-terminal ...... cts survival and proliferation
@en
P2093
Amy D Hartman
Annique Wilson-Weekes
Attaya Suvannasankha
Carissa A Phillips
Gem S Burgess
H Scott Boswell
Katie J Hincher
Larry D Cripe
P304
P356
10.1016/J.EXPHEM.2006.05.019
P407
P577
2006-10-01T00:00:00Z