Identification of four novel human genes amplified and overexpressed in breast carcinoma and localized to the q11-q21.3 region of chromosome 17
about
Metastatic Lymph Node 51, a novel nucleo-cytoplasmic protein overexpressed in breast cancerLasp-1 (MLN 50) defines a new LIM protein subfamily characterized by the association of LIM and SH3 domainsMLN64 exhibits homology with the steroidogenic acute regulatory protein (STAR) and is over-expressed in human breast carcinomasCloning of ligand targets: systematic isolation of SH3 domain-containing proteinsNuclear import of LASP-1 is regulated by phosphorylation and dynamic protein-protein interactionsImpaired neural tube closure, axial skeleton malformations, and tracheal ring disruption in TRAF4-deficient mice.CD30-dependent degradation of TRAF2: implications for negative regulation of TRAF signaling and the control of cell survivalMLN64 contains a domain with homology to the steroidogenic acute regulatory protein (StAR) that stimulates steroidogenesisLasp-1, a novel type of actin-binding protein accumulating in cell membrane extensionsTRAF-4 expression in epithelial progenitor cells. Analysis in normal adult, fetal, and tumor tissuesTRAF4 Is a Novel Phosphoinositide-Binding Protein Modulating Tight Junctions and Favoring Cell MigrationC2PA, a new protein expressed during mouse spermatogenesisIdentification and characterization of the cytoplasmic protein TRAF4 as a p53-regulated proapoptotic geneInvolvement of TRAF4 in oxidative activation of c-Jun N-terminal kinaseBinding domain-driven intracellular trafficking of sterols for synthesis of steroid hormones, bile acids and oxysterolsGene characterization, promoter analysis, and chromosomal localization of human bleomycin hydrolaseTRAF4 deficiency leads to tracheal malformation with resulting alterations in air flow to the lungsEpigenetically regulated miR-145 suppresses colon cancer invasion and metastasis by targeting LASP1.LASP1-S100A11 axis promotes colorectal cancer aggressiveness by modulating TGFβ/Smad signalingUpregulated LASP-1 correlates with a malignant phenotype and its potential therapeutic role in human cholangiocarcinoma.An update on the LIM and SH3 domain protein 1 (LASP1): a versatile structural, signaling, and biomarker proteinTumor suppressor miR-1 restrains epithelial-mesenchymal transition and metastasis of colorectal carcinoma via the MAPK and PI3K/AKT pathway.Tumor-suppressive microRNA-218 inhibits cancer cell migration and invasion via targeting of LASP1 in prostate cancer.Role of hepatitis B virus X protein in regulating LIM and SH3 protein 1 (LASP-1) expression to mediate proliferation and migration of hepatoma cellsNuclear localisation of LASP-1 correlates with poor long-term survival in female breast cancer.Contribution of the LIM domain and nebulin-repeats to the interaction of Lasp-2 with actin filaments and focal adhesions.Targeted disruption of the Lasp-1 gene is linked to increases in histamine-stimulated gastric HCl secretionThe LIM and SH3 domain protein family: structural proteins or signal transducers or both?Overexpression of LASP-1 mediates migration and proliferation of human ovarian cancer cells and influences zyxin localisationShort-term retention of actin filament binding proteins on lamellipodial actin bundles.Regulation of cell migration and survival by focal adhesion targeting of Lasp-1Actin binding of human LIM and SH3 protein is regulated by cGMP- and cAMP-dependent protein kinase phosphorylation on serine 146.Functional characterization of the MENTAL domain.Isolation, characterization, and cDNA sequence of a carotenoid binding protein from the silk gland of Bombyx mori larvae.Identification of amplified and expressed genes in breast cancer by comparative hybridization onto microarrays of randomly selected cDNA clones.MENTHO, a MLN64 homologue devoid of the START domain.Nuclear localization and cytosolic overexpression of LASP-1 correlates with tumor size and nodal-positivity of human breast carcinomaNovel association of APC with intermediate filaments identified using a new versatile APC antibodySelective release of microRNA species from normal and malignant mammary epithelial cells.Upregulation of the long non-coding RNA PVT1 promotes esophageal squamous cell carcinoma progression by acting as a molecular sponge of miR-203 and LASP1
P2860
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P2860
Identification of four novel human genes amplified and overexpressed in breast carcinoma and localized to the q11-q21.3 region of chromosome 17
description
1995 nî lūn-bûn
@nan
1995 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
Identification of four novel h ...... -q21.3 region of chromosome 17
@ast
Identification of four novel h ...... -q21.3 region of chromosome 17
@en
Identification of four novel h ...... -q21.3 region of chromosome 17
@nl
type
label
Identification of four novel h ...... -q21.3 region of chromosome 17
@ast
Identification of four novel h ...... -q21.3 region of chromosome 17
@en
Identification of four novel h ...... -q21.3 region of chromosome 17
@nl
prefLabel
Identification of four novel h ...... -q21.3 region of chromosome 17
@ast
Identification of four novel h ...... -q21.3 region of chromosome 17
@en
Identification of four novel h ...... -q21.3 region of chromosome 17
@nl
P2093
P921
P3181
P356
P1433
P1476
Identification of four novel h ...... -q21.3 region of chromosome 17
@en
P2093
P304
P3181
P356
10.1006/GENO.1995.1163
P407
P577
1995-08-01T00:00:00Z