about
Deubiquitylating enzymes and diseaseThe deubiquitinating enzyme USP2a regulates the p53 pathway by targeting Mdm2USP10 regulates p53 localization and stability by deubiquitinating p53USP17 regulates Ras activation and cell proliferation by blocking RCE1 activityRegulation and cellular roles of ubiquitin-specific deubiquitinating enzymesThe Regulation of DNA Damage Tolerance by Ubiquitin and Ubiquitin-Like ModifiersMotif co-regulation and co-operativity are common mechanisms in transcriptional, post-transcriptional and post-translational regulationContributions of Epstein-Barr nuclear antigen 1 (EBNA1) to cell immortalization and survivalFunctional diversity and structural disorder in the human ubiquitination pathwayDeubiquitylation machinery is required for embryonic polarity in Caenorhabditis elegansMolecular Basis for Bre5 Cofactor Recognition by the Ubp3 Deubiquitylating EnzymeBilateral inhibition of HAUSP deubiquitinase by a viral interferon regulatory factor proteinA Role for USP7 in DNA ReplicationStructure and Catalytic Regulatory Function of Ubiquitin Specific Protease 11 N-Terminal and Ubiquitin-like DomainsThe Ubp15 deubiquitinase promotes timely entry into S phase in Saccharomyces cerevisiaeModulation of the p53/MDM2 interplay by HAUSP inhibitorsp53 Proteoforms and Intrinsic Disorder: An Illustration of the Protein Structure-Function Continuum ConceptThe shelterin component TPP1 is a binding partner and substrate for the deubiquitinating enzyme USP7The role of UBL domains in ubiquitin-specific proteasesCrystal Structure of USP7 Ubiquitin-like Domains with an ICP0 Peptide Reveals a Novel Mechanism Used by Viral and Cellular Proteins to Target USP7USP7 Acts as a Molecular Rheostat to Promote WASH-Dependent Endosomal Protein Recycling and Is Mutated in a Human Neurodevelopmental DisorderDeubiquitination of Tip60 by USP7 determines the activity of the p53-dependent apoptotic pathwayUbiquitin-specific protease 7 is a regulator of ubiquitin-conjugating enzyme UbE2E1.Epstein-Barr nuclear antigen 1 contributes to nasopharyngeal carcinoma through disruption of PML nuclear bodies.USP7/HAUSP promotes the sequence-specific DNA binding activity of p53.The molecular determinants for distinguishing between ubiquitin and NEDD8 by USP2.TGF-β upregulates the translation of USP15 via the PI3K/AKT pathway to promote p53 stability.The herpesvirus associated ubiquitin specific protease, USP7, is a negative regulator of PML proteins and PML nuclear bodies.WDR79 promotes the proliferation of non-small cell lung cancer cells via USP7-mediated regulation of the Mdm2-p53 pathwaySRC-3 coactivator regulates cell resistance to cytotoxic stress via TRAF4-mediated p53 destabilization.Characterization of RanBPM molecular determinants that control its subcellular localization.Differential roles of ATM- and Chk2-mediated phosphorylations of Hdmx in response to DNA damage.Regulation of the DNA damage response by ubiquitin conjugation.Reduced association of anti-apoptotic protein Mcl-1 with E3 ligase Mule increases the stability of Mcl-1 in breast cancer cells.USP7 overexpression predicts a poor prognosis in lung squamous cell carcinoma and large cell carcinoma.A survey of the interactome of Kaposi's sarcoma-associated herpesvirus ORF45 revealed its binding to viral ORF33 and cellular USP7, resulting in stabilization of ORF33 that is required for production of progeny virusesAnnexin-1 regulated by HAUSP is essential for UV-induced damage response.Changes in the nasopharyngeal carcinoma nuclear proteome induced by the EBNA1 protein of Epstein-Barr virus reveal potential roles for EBNA1 in metastasis and oxidative stress responses.HAUSP-nucleolin interaction is regulated by p53-Mdm2 complex in response to DNA damage responseThe ubiquitin-specific protease USP7 modulates the replication of Kaposi's sarcoma-associated herpesvirus latent episomal DNA
P2860
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P2860
description
2006 nî lūn-bûn
@nan
2006 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի մարտին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Molecular recognition of p53 and MDM2 by USP7/HAUSP
@ast
Molecular recognition of p53 and MDM2 by USP7/HAUSP
@en
Molecular recognition of p53 and MDM2 by USP7/HAUSP
@en-gb
Molecular recognition of p53 and MDM2 by USP7/HAUSP
@nl
type
label
Molecular recognition of p53 and MDM2 by USP7/HAUSP
@ast
Molecular recognition of p53 and MDM2 by USP7/HAUSP
@en
Molecular recognition of p53 and MDM2 by USP7/HAUSP
@en-gb
Molecular recognition of p53 and MDM2 by USP7/HAUSP
@nl
prefLabel
Molecular recognition of p53 and MDM2 by USP7/HAUSP
@ast
Molecular recognition of p53 and MDM2 by USP7/HAUSP
@en
Molecular recognition of p53 and MDM2 by USP7/HAUSP
@en-gb
Molecular recognition of p53 and MDM2 by USP7/HAUSP
@nl
P2093
P2860
P50
P3181
P356
P1476
Molecular recognition of p53 and MDM2 by USP7/HAUSP
@en
P2093
Lori Frappier
Shili Duan
P2860
P2888
P304
P3181
P356
10.1038/NSMB1067
P407
P577
2006-03-01T00:00:00Z
P5875
P6179
1047675721