Targeting and activation of Rac1 are mediated by the exchange factor beta-Pix.
about
Type I PIPK-alpha regulates directed cell migration by modulating Rac1 plasma membrane targeting and activationRac1-induced cell migration requires membrane recruitment of the nuclear oncogene SETNox1 activation by βPix and the role of Ser-340 phosphorylationAnalysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturationA palmitoylation switch mechanism regulates Rac1 function and membrane organization.The Rac1 polybasic region is required for interaction with its effector PRK1Affixin activates Rac1 via betaPIX in C2C12 myoblastEndogenous RhoG is dispensable for integrin-mediated cell spreading but contributes to Rac-independent migration.GTP-binding proteins of the Rho/Rac family: regulation, effectors and functions in vivoThe on-off relationship of Rho and Rac during integrin-mediated adhesion and cell migrationThe Rac1 hypervariable region in targeting and signaling: a tail of many storiesRho GAPs and GEFs: controling switches in endothelial cell adhesionComputer vision profiling of neurite outgrowth dynamics reveals spatiotemporal modularity of Rho GTPase signalingKCC2 regulates actin dynamics in dendritic spines via interaction with β-PIX.Phosphorylation of tyrosine 285 of PAK1 facilitates βPIX/GIT1 binding and adhesion turnoverNon-muscle myosin II regulates neuronal actin dynamics by interacting with guanine nucleotide exchange factorsA novel interaction between atrophin-interacting protein 4 and beta-p21-activated kinase-interactive exchange factor is mediated by an SH3 domainA phosphorylation switch controls the spatiotemporal activation of Rho GTPases in directional cell migrationBiochemical and functional characterization of the interaction between liprin-α1 and GIT1: implications for the regulation of cell motilityDissecting activation of the PAK1 kinase at protrusions in living cells.Localized activation of p21-activated kinase controls neuronal polarity and morphologyCool-1/βPIX functions as a guanine nucleotide exchange factor in the cycling of Cdc42 to regulate insulin secretionRosiglitazone and AS601245 decrease cell adhesion and migration through modulation of specific gene expression in human colon cancer cellsMultiparametric Analysis of Cell Shape Demonstrates that β-PIX Directly Couples YAP Activation to Extracellular Matrix AdhesionCoordination of Rho GTPase activities during cell protrusionInvestigation of the Interaction between Cdc42 and Its Effector TOCA1: HANDOVER OF Cdc42 TO THE ACTIN REGULATOR N-WASP IS FACILITATED BY DIFFERENTIAL BINDING AFFINITIES.The N-terminal DH-PH domain of Trio induces cell spreading and migration by regulating lamellipodia dynamics in a Rac1-dependent fashion.Rac1 recruits the adapter protein CMS/CD2AP to cell-cell contacts.Identification of a bipartite focal adhesion localization signal in RhoU/Wrch-1, a Rho family GTPase that regulates cell adhesion and migration.Identification of phosphorylation sites in betaPIX and PAK1Impedance analysis of GPCR-mediated changes in endothelial barrier function: overview and fundamental considerations for stable and reproducible measurementsPAK-PIX interactions regulate adhesion dynamics and membrane protrusion to control neurite outgrowth.The Rho-GEF Trio regulates a novel pro-inflammatory pathway through the transcription factor Ets2.The Rho-guanine nucleotide exchange factor Trio controls leukocyte transendothelial migration by promoting docking structure formation.Paxillin-kinase-linker tyrosine phosphorylation regulates directional cell migration.Endogenous ARF6 interacts with Rac1 upon angiotensin II stimulation to regulate membrane ruffling and cell migration.FAK potentiates Rac1 activation and localization to matrix adhesion sites: a role for betaPIX.PAK1-mediated activation of ERK1/2 regulates lamellipodial dynamics.Pak3 inhibits local actin filament formation to regulate global cell polarity.PAK kinase regulates Rac GTPase and is a potential target in human schwannomas
P2860
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P2860
Targeting and activation of Rac1 are mediated by the exchange factor beta-Pix.
description
2006 nî lūn-bûn
@nan
2006 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Targeting and activation of Rac1 are mediated by the exchange factor beta-Pix
@nl
Targeting and activation of Rac1 are mediated by the exchange factor beta-Pix.
@ast
Targeting and activation of Rac1 are mediated by the exchange factor beta-Pix.
@en
Targeting and activation of Rac1 are mediated by the exchange factor beta-Pix.
@en-gb
type
label
Targeting and activation of Rac1 are mediated by the exchange factor beta-Pix
@nl
Targeting and activation of Rac1 are mediated by the exchange factor beta-Pix.
@ast
Targeting and activation of Rac1 are mediated by the exchange factor beta-Pix.
@en
Targeting and activation of Rac1 are mediated by the exchange factor beta-Pix.
@en-gb
prefLabel
Targeting and activation of Rac1 are mediated by the exchange factor beta-Pix
@nl
Targeting and activation of Rac1 are mediated by the exchange factor beta-Pix.
@ast
Targeting and activation of Rac1 are mediated by the exchange factor beta-Pix.
@en
Targeting and activation of Rac1 are mediated by the exchange factor beta-Pix.
@en-gb
P2093
P2860
P3181
P356
P1476
Targeting and activation of Rac1 are mediated by the exchange factor beta-Pix.
@en
P2093
Jean Paul ten Klooster
Peter L Hordijk
Zahara M Jaffer
P2860
P304
P3181
P356
10.1083/JCB.200509096
P407
P577
2006-02-21T00:00:00Z