Beta-arrestin-dependent regulation of the cofilin pathway downstream of protease-activated receptor-2
about
Beta-arrestins and heterotrimeric G-proteins: collaborators and competitors in signal transductionFunction and Regulation of Heterotrimeric G Proteins during Chemotaxisβ-Arrestin2 regulates lysophosphatidic acid-induced human breast tumor cell migration and invasion via Rap1 and IQGAP1Evolutionary and Structural Analyses of Mammalian Haloacid Dehalogenase-type Phosphatases AUM and Chronophin Provide Insight into the Basis of Their Different Substrate SpecificitiesChronophin Dimerization Is Required for Proper Positioning of Its Substrate Specificity Loopbeta-Arrestins scaffold cofilin with chronophin to direct localized actin filament severing and membrane protrusions downstream of protease-activated receptor-2.Cofilin under control of β-arrestin-2 in NMDA-dependent dendritic spine plasticity, long-term depression (LTD), and learningPhosphorylation of protease-activated receptor-2 differentially regulates desensitization and internalization.Tissue factor and PAR2 signaling in the tumor microenvironmentβArrestin1 regulates the guanine nucleotide exchange factor RasGRF2 expression and the small GTPase Rac-mediated formation of membrane protrusion and cell motility.Beta-arrestin inhibits CAMKKbeta-dependent AMPK activation downstream of protease-activated-receptor-2.Beyond desensitization: physiological relevance of arrestin-dependent signaling.Role for β-arrestin in mediating paradoxical β2AR and PAR2 signaling in asthma.Global phosphorylation analysis of beta-arrestin-mediated signaling downstream of a seven transmembrane receptor (7TMR).Tissue factor-protease-activated receptor 2 signaling promotes diet-induced obesity and adipose inflammation.The quorum sensing peptides PhrG, CSP and EDF promote angiogenesis and invasion of breast cancer cells in vitro.Cofilin, a hypoxia-regulated protein in murine lungs identified by 2DE: role of the cytoskeletal protein cofilin in pulmonary hypertension.Apical and basolateral pools of proteinase-activated receptor-2 direct distinct signaling events in the intestinal epithelium.Cooperation of tissue factor cytoplasmic domain and PAR2 signaling in breast cancer development.Breast cancer phenotypes regulated by tissue factor-factor VII pathway: Possible therapeutic targets.Role of the protein C receptor in cancer progression.Recent advances on the δ opioid receptor: from trafficking to function.The protease-activated receptor-2-specific agonists 2-aminothiazol-4-yl-LIGRL-NH2 and 6-aminonicotinyl-LIGRL-NH2 stimulate multiple signaling pathways to induce physiological responses in vitro and in vivoDifferential expression of arrestins is a predictor of breast cancer progression and survival.Emerging paradigms of β-arrestin-dependent seven transmembrane receptor signalingArrestin development: emerging roles for beta-arrestins in developmental signaling pathwaysArrestins 2 and 3 differentially regulate ETA and P2Y2 receptor-mediated cell signaling and migration in arterial smooth muscle.Fulfilling the Promise of "Biased" G Protein-Coupled Receptor Agonism.Acute activation of β2-adrenergic receptor regulates focal adhesions through βArrestin2- and p115RhoGEF protein-mediated activation of RhoA.GnRH Neuron-Specific Ablation of Gαq/11 Results in Only Partial Inactivation of the Neuroendocrine-Reproductive Axis in Both Male and Female Mice: In Vivo Evidence for Kiss1r-Coupled Gαq/11-Independent GnRH Secretionβ-Arrestin-2 mediates the proinflammatory effects of proteinase-activated receptor-2 in the airway.Inhibition of tissue factor signaling suppresses tumor growthDivergent β-arrestin-dependent signaling events are dependent upon sequences within G-protein-coupled receptor C terminiProtease-activated receptor (PAR) 2, but not PAR1, signaling promotes the development of mammary adenocarcinoma in polyoma middle T mice.Proteinases and signalling: pathophysiological and therapeutic implications via PARs and more.Molecular Pharmacology of δ-Opioid Receptors.Tissue factor in cancer progression and angiogenesis.Proteinase-activated receptors (PARs) - focus on receptor-receptor-interactions and their physiological and pathophysiological impactProteinase-activated receptor 2 (PAR-2) in gastrointestinal and pancreatic pathophysiology, inflammation and neoplasia.Agonist-biased signaling via proteinase activated receptor-2: differential activation of calcium and mitogen-activated protein kinase pathways.
P2860
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P2860
Beta-arrestin-dependent regulation of the cofilin pathway downstream of protease-activated receptor-2
description
2007 nî lūn-bûn
@nan
2007 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Beta-arrestin-dependent regula ...... protease-activated receptor-2
@ast
Beta-arrestin-dependent regula ...... protease-activated receptor-2
@en
Beta-arrestin-dependent regula ...... protease-activated receptor-2
@en-gb
Beta-arrestin-dependent regula ...... protease-activated receptor-2
@nl
type
label
Beta-arrestin-dependent regula ...... protease-activated receptor-2
@ast
Beta-arrestin-dependent regula ...... protease-activated receptor-2
@en
Beta-arrestin-dependent regula ...... protease-activated receptor-2
@en-gb
Beta-arrestin-dependent regula ...... protease-activated receptor-2
@nl
prefLabel
Beta-arrestin-dependent regula ...... protease-activated receptor-2
@ast
Beta-arrestin-dependent regula ...... protease-activated receptor-2
@en
Beta-arrestin-dependent regula ...... protease-activated receptor-2
@en-gb
Beta-arrestin-dependent regula ...... protease-activated receptor-2
@nl
P2093
P2860
P356
P1476
Beta-arrestin-dependent regula ...... protease-activated receptor-2
@en
P2093
Gary M Bokoch
Kathryn A DeFea
Maria Zoudilova
Puneet Kumar
P2860
P304
P356
10.1074/JBC.M701391200
P407
P577
2007-07-13T00:00:00Z