The tumor-suppressor gene ARHI (DIRAS3) suppresses ovarian cancer cell migration through inhibition of the Stat3 and FAK/Rho signaling pathways
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Involvement of autophagy in ovarian cancer: a working hypothesisLeukotriene B4 receptor-2 promotes invasiveness and metastasis of ovarian cancer cells through signal transducer and activator of transcription 3 (STAT3)-dependent up-regulation of matrix metalloproteinase 2S-phase cell cycle arrest, apoptosis, and molecular mechanisms of aplasia ras homolog member I-induced human ovarian cancer SKOV3 cell lines.JMJD2A contributes to breast cancer progression through transcriptional repression of the tumor suppressor ARHIARHI (DIRAS3) induces autophagy in ovarian cancer cells by downregulating the epidermal growth factor receptor, inhibiting PI3K and Ras/MAP signaling and activating the FOXo3a-mediated induction of Rab7DIRAS3 regulates the autophagosome initiation complex in dormant ovarian cancer cellsJAK2/STAT3 targeted therapy suppresses tumor invasion via disruption of the EGFRvIII/JAK2/STAT3 axis and associated focal adhesion in EGFRvIII-expressing glioblastoma.The tumor suppressor DiRas3 forms a complex with H-Ras and C-RAF proteins and regulates localization, dimerization, and kinase activity of C-RAFLoss of ARHI expression in colon cancer and its clinical significance.Cytoskeletal rearrangement and Src and PI-3K-dependent Akt activation control GABA(B)R-mediated chemotaxisARHI (DIRAS3)-mediated autophagy-associated cell death enhances chemosensitivity to cisplatin in ovarian cancer cell lines and xenografts.High LIFr expression stimulates melanoma cell migration and is associated with unfavorable prognosis in melanoma.Sphingosine 1-phosphate (S1P) receptors 1 and 2 coordinately induce mesenchymal cell migration through S1P activation of complementary kinase pathwaysNDN is an imprinted tumor suppressor gene that is downregulated in ovarian cancers through genetic and epigenetic mechanisms.Imprinted chromatin around DIRAS3 regulates alternative splicing of GNG12-AS1, a long noncoding RNA.Epithelial-mesenchymal transition enhances nanoscale actin filament dynamics of ovarian cancer cells.Allelic imbalance in 1p, 7q, 9p, 11p, 12q and 16q regions in non-small cell lung carcinoma and its clinical association: a pilot study.Expression and epigenetic regulation of angiogenesis-related factors during dormancy and recurrent growth of ovarian carcinomaThe tumor suppressor gene ARHI (DIRAS3) inhibits ovarian cancer cell migration through multiple mechanisms.JAK2 inhibition for the treatment of hematologic and solid malignancies.Involvement of autophagy in cervical, endometrial and ovarian cancer.STAT3 in Cancer-Friend or Foe?Effects of ARHI on breast cancer cell biological behavior regulated by microRNA-221.Mechanisms of Metastatic Tumor Dormancy.The role of microRNAs in prostate cancer progression.The expression of aplysia ras homolog I (ARHI) and its inhibitory effect on cell biological behavior in esophageal squamous cell carcinomaRevealing protein networks and gene-drug connectivity in cancer from direct information.JMJD2A-dependent silencing of Sp1 in advanced breast cancer promotes metastasis by downregulation of DIRAS3.Effect of ARHI on lung cancer cell proliferation, apoptosis and invasion in vitro.The tumour suppressor DiRas3 interacts with C-RAF and downregulates MEK activity to restrict cell migration.Resveratrol inhibits IL-6-induced ovarian cancer cell migration through epigenetic up-regulation of autophagy.Effects of ARHI on cell cycle progression and apoptosis levels of breast cancer cells.Human Cytomegalovirus UL111A and US27 gene products enhance the CXCL12/CXCR4 signaling axis via distinct mechanisms.ARHI is a novel epigenetic silenced tumor suppressor in sporadic pheochromocytoma.
P2860
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P2860
The tumor-suppressor gene ARHI (DIRAS3) suppresses ovarian cancer cell migration through inhibition of the Stat3 and FAK/Rho signaling pathways
description
2012 nî lūn-bûn
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2012 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հունվարին հրատարակված գիտական հոդված
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2012年の論文
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2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
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name
The tumor-suppressor gene ARHI ...... and FAK/Rho signaling pathways
@ast
The tumor-suppressor gene ARHI ...... and FAK/Rho signaling pathways
@en
The tumor-suppressor gene ARHI ...... and FAK/Rho signaling pathways
@en-gb
The tumor-suppressor gene ARHI ...... and FAK/Rho signaling pathways
@nl
type
label
The tumor-suppressor gene ARHI ...... and FAK/Rho signaling pathways
@ast
The tumor-suppressor gene ARHI ...... and FAK/Rho signaling pathways
@en
The tumor-suppressor gene ARHI ...... and FAK/Rho signaling pathways
@en-gb
The tumor-suppressor gene ARHI ...... and FAK/Rho signaling pathways
@nl
prefLabel
The tumor-suppressor gene ARHI ...... and FAK/Rho signaling pathways
@ast
The tumor-suppressor gene ARHI ...... and FAK/Rho signaling pathways
@en
The tumor-suppressor gene ARHI ...... and FAK/Rho signaling pathways
@en-gb
The tumor-suppressor gene ARHI ...... and FAK/Rho signaling pathways
@nl
P2093
P2860
P356
P1433
P1476
The tumor-suppressor gene ARHI ...... and FAK/Rho signaling pathways
@en
P2093
D B Badgwell
M Andreeff
P2860
P2888
P356
10.1038/ONC.2011.213
P407
P577
2012-01-05T00:00:00Z
P5875
P6179
1041529811