The tumour suppressor RASSF1A regulates mitosis by inhibiting the APC-Cdc20 complex
about
Release of RASSF1C from the nucleus by Daxx degradation links DNA damage and SAPK/JNK activationSpatiotemporal regulation of the kinase Mst1 by binding protein RAPL is critical for lymphocyte polarity and adhesionThe STARD9/Kif16a kinesin associates with mitotic microtubules and regulates spindle pole assemblyFez1/Lzts1 absence impairs Cdk1/Cdc25C interaction during mitosis and predisposes mice to cancer development.Emi1 stably binds and inhibits the anaphase-promoting complex/cyclosome as a pseudosubstrate inhibitorThe RASSF1A tumor suppressor restrains anaphase-promoting complex/cyclosome activity during the G1/S phase transition to promote cell cycle progression in human epithelial cellsLocal activation of Rap1 contributes to directional vascular endothelial cell migration accompanied by extension of microtubules on which RAPL, a Rap1-associating molecule, localizesThe tumour suppressor RASSF1A promotes MDM2 self-ubiquitination by disrupting the MDM2-DAXX-HAUSP complexThe scaffold protein CNK1 interacts with the tumor suppressor RASSF1A and augments RASSF1A-induced cell deathMicrotubule-associated protein 1S (MAP1S) bridges autophagic components with microtubules and mitochondria to affect autophagosomal biogenesis and degradationDeficiency in SNM1 abolishes an early mitotic checkpoint induced by spindle stressThe significance of genetics for cholangiocarcinoma developmentRASSF tumor suppressor gene family: biological functions and regulationFunctional characterization of Anaphase Promoting Complex/Cyclosome (APC/C) E3 ubiquitin ligases in tumorigenesisA cell cycle timer for asymmetric spindle positioning8p22 MTUS1 gene product ATIP3 is a novel anti-mitotic protein underexpressed in invasive breast carcinoma of poor prognosisInhibition of APCCdh1 activity by Cdh1/Acm1/Bmh1 ternary complex formation.The Ste20-like kinase Mst2 activates the human large tumor suppressor kinase Lats1The growth and tumor suppressor NORE1A is a cytoskeletal protein that suppresses growth by inhibition of the ERK pathwayMouse emi1 has an essential function in mitotic progression during early embryogenesisThe E4F protein is required for mitotic progression during embryonic cell cyclesMenin determines K-RAS proliferative outputs in endocrine cellsLoss of Cdc20 causes a securin-dependent metaphase arrest in two-cell mouse embryosThe anaphase promoting complex/cyclosome: a machine designed to destroyDNA IR-Double Strand Breaks (DSBs) and cellular response via ATMMicrotubule segment stabilization by RASSF1A is required for proper microtubule dynamics and Golgi integrity.Regulation of mitosis and taxane response by Daxx and Rassf1.Clinical implications of promoter hypermethylation in RASSF1A and MGMT in retinoblastomaThe Ras-association domain family (RASSF) members and their role in human tumourigenesis.Mitotic phosphorylation of the anaphase-promoting complex inhibitory subunit Mnd2 is necessary for efficient progression through meiosis i.Association of diminished expression of RASSF1A with promoter methylation in primary gastric cancer from patients of central China.RASSF1A protein expression and correlation with clinicopathological parameters in renal cell carcinomaCdc20: a potential novel therapeutic target for cancer treatmentDistinct epigenetic domains separated by a CTCF bound insulator between the tandem genes, BLU and RASSF1ARASSF1A polymorphism A133S is associated with early onset breast cancer in BRCA1/2 mutation carriers.Chromatin inactivation precedes de novo DNA methylation during the progressive epigenetic silencing of the RASSF1A promoterCross-regulation between oncogenic BRAF(V600E) kinase and the MST1 pathway in papillary thyroid carcinomaRegulation of APC/C activators in mitosis and meiosis.Tumor suppressor RASSF1A promoter: p53 binding and methylation.Promoter Methylation in Prostate Cancer and its Application for the Early Detection of Prostate Cancer Using Serum and Urine Samples.
P2860
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P2860
The tumour suppressor RASSF1A regulates mitosis by inhibiting the APC-Cdc20 complex
description
2004 nî lūn-bûn
@nan
2004 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
The tumour suppressor RASSF1A regulates mitosis by inhibiting the APC-Cdc20 complex
@ast
The tumour suppressor RASSF1A regulates mitosis by inhibiting the APC-Cdc20 complex
@en
The tumour suppressor RASSF1A regulates mitosis by inhibiting the APC-Cdc20 complex
@en-gb
The tumour suppressor RASSF1A regulates mitosis by inhibiting the APC-Cdc20 complex
@nl
type
label
The tumour suppressor RASSF1A regulates mitosis by inhibiting the APC-Cdc20 complex
@ast
The tumour suppressor RASSF1A regulates mitosis by inhibiting the APC-Cdc20 complex
@en
The tumour suppressor RASSF1A regulates mitosis by inhibiting the APC-Cdc20 complex
@en-gb
The tumour suppressor RASSF1A regulates mitosis by inhibiting the APC-Cdc20 complex
@nl
prefLabel
The tumour suppressor RASSF1A regulates mitosis by inhibiting the APC-Cdc20 complex
@ast
The tumour suppressor RASSF1A regulates mitosis by inhibiting the APC-Cdc20 complex
@en
The tumour suppressor RASSF1A regulates mitosis by inhibiting the APC-Cdc20 complex
@en-gb
The tumour suppressor RASSF1A regulates mitosis by inhibiting the APC-Cdc20 complex
@nl
P2093
P2860
P356
P1433
P1476
The tumour suppressor RASSF1A regulates mitosis by inhibiting the APC-Cdc20 complex
@en
P2093
Dae-Sik Lim
Eui-Ju Choi
Hojoong Kim
Hyun Kyung Hong
Jhingook Kim
Jin Sook Chang
Jin Woo Kim
Joo Hyun Lee
Marc W Kirschner
P2860
P2888
P304
P356
10.1038/NCB1091
P407
P577
2004-02-01T00:00:00Z
P5875
P6179
1016419469