Alternative chemical modifications reverse the binding orientation of a pharmacophore scaffold in the active site of macrophage migration inhibitory factor - Wikidata - awgldk - TriplyDB

Alternative chemical modifications reverse the binding orientation of a pharmacophore scaffold in the active site of macrophage migration inhibitory factor

Alternative chemical modifications reverse the binding orientation of a pharmacophore scaffold in the active site of macrophage migration inhibitory factor

http://www.wikidata.org/entity/Q24306941

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Thyroxine is a potential endogenous antagonist of macrophage migration inhibitory factor (MIF) activity The crystal structures of macrophage migration inhibitory factor from Plasmodium falciparum and Plasmodium berghei A Novel, Macrophage Migration Inhibitory Factor Suicide Substrate Inhibits Motility and Growth of Lung Cancer Cells Structural and Kinetic Analyses of Macrophage Migration Inhibitory Factor Active Site Interactions † ‡Allosteric inhibition of macrophage migration inhibitory factor revealed by ibudilast.Structural Interactions Dictate the Kinetics of Macrophage Migration Inhibitory Factor Inhibition by Different Cancer-Preventive Isothiocyanates Drug Repositioning and Pharmacophore Identification in the Discovery of Hookworm MIF Inhibitors MIF intersubunit disulfide mutant antagonist supports activation of CD74 by endogenous MIF trimer at physiologic concentrations ISO-66, a novel inhibitor of macrophage migration, shows efficacy in melanoma and colon cancer models A new class of isothiocyanate-based irreversible inhibitors of macrophage migration inhibitory factor.Expression and function of macrophage migration inhibitory factor (MIF) in melioidosis.Methyl ({[(4E)-1,3-dimethyl-2,6-di-phenyl-piperidin-4-yl-idene]amino}-oxy)acetate Aza-derivatives of resveratrol are potent macrophage migration inhibitory factor inhibitors.(E)-3-Methyl-2,6-di-phenyl-piperidin-4-one O-(3-methyl-benzo-yl)oxime.Macrophage migration inhibitory factor mediates hypoxia-induced pulmonary hypertension.Age-dependent alterations in the inflammatory response to pulmonary challenge Orthologs of macrophage migration inhibitory factor from parasitic nematodes Identification of Iguratimod as an Inhibitor of Macrophage Migration Inhibitory Factor (MIF) with Steroid-sparing Potential.Crystallographic and receptor binding characterization of Plasmodium falciparum macrophage migration inhibitory factor complexed to two potent inhibitors.Virtual Screening of Some Active Human Macrophage Migration Inhibitory Factor Antagonists.Novel arylazoarylmethane as potential inhibitor of macrophage migration inhibitory factor.

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P2860

Alternative chemical modifications reverse the binding orientation of a pharmacophore scaffold in the active site of macrophage migration inhibitory factor

http://www.wikidata.org/entity/Q24306941

description

2007 nî lūn-bûn

@nan

2007 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2007 թվականի օգոստոսին հրատարակված գիտական հոդված

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2007年の論文

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2007年学术文章

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2007年学术文章

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2007年学术文章

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2007年学术文章

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2007年学术文章

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2007年學術文章

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name

Alternative chemical modificat ...... ge migration inhibitory factor

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Alternative chemical modificat ...... ge migration inhibitory factor

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Journal of Biological Chemistry

P1476

Alternative chemical modificat ...... ge migration inhibitory factor

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P2093

Bayan Aljabari

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Darrin Dabideen

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Edmund J Miller

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Elias Lolis

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Gregg V Crichlow

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Kai Fan Cheng

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Mahendar Ochani

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Valentin A Pavlov

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Yousef Al-Abed

http://www.w3.org/2001/XMLSchema#string

P2860

Crystal structure at 2.6-A resolution of human macrophage migration inhibitory factor

The immunoregulatory mediator macrophage migration inhibitory factor (MIF) catalyzes a tautomerization reaction

Improved methods for building protein models in electron density maps and the location of errors in these models

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

Pro-1 of macrophage migration inhibitory factor functions as a catalytic base in the phenylpyruvate tautomerase activity

The tautomerase active site of macrophage migration inhibitory factor is a potential target for discovery of novel anti-inflammatory agents

Crystal structure of the macrophage migration inhibitory factor from rat liver

Coot: model-building tools for molecular graphics

Implementation of molecular replacement in AMoRe

Macrophage migration inhibitory factor (MIF): mechanisms of action and role in disease

P304

23089-95

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scholarly article

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10.1074/JBC.M701825200

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32

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282

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2007-08-10T00:00:00Z

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17526494

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P921

Macrophage migration inhibitory factor

protein homotrimerization

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3684284

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