The structure of Atg4B-LC3 complex reveals the mechanism of LC3 processing and delipidation during autophagy
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Are mitochondrial reactive oxygen species required for autophagy?Structural determinants in GABARAP required for the selective binding and recruitment of ALFY to LC3B-positive structuresBinding of the Atg1/ULK1 kinase to the ubiquitin-like protein Atg8 regulates autophagyImaging protein complex formation in the autophagy pathway: analysis of the interaction of LC3 and Atg4B(C74A) in live cells using Förster resonance energy transfer and fluorescence recovery after photobleachingRole of autophagy in megakaryocyte differentiation and platelet formationThe autophagy-lysosomal system in subarachnoid haemorrhageReceptor-mediated mitophagy in yeast and mammalian systemsAutophagic processes in yeast: mechanism, machinery and regulationThe role of ALFY in selective autophagyER stress-induced cell death mechanismsAtomistic autophagy: the structures of cellular self-digestionStructure of Ubiquitin-fold Modifier 1-specific Protease UfSP2Autophagy-related Protein 32 Acts as Autophagic Degron and Directly Initiates MitophagyCaspase cleavage of Atg4D stimulates GABARAP-L1 processing and triggers mitochondrial targeting and apoptosis.FYCO1 Contains a C-terminally Extended, LC3A/B-preferring LC3-interacting Region (LIR) Motif Required for Efficient Maturation of Autophagosomes during Basal AutophagySelective autophagy mediated by autophagic adapter proteinsC/EBPβ regulates sensitivity to bortezomib in prostate cancer cells by inducing REDD1 and autophagosome-lysosome fusionAutophagy gene expression profiling identifies a defective microtubule-associated protein light chain 3A mutant in cancerDistribution, cleavage and lipidation of Atg8 fusion proteins in Spodoptera litura Sl-HP cells.ATM kinase sustains breast cancer stem-like cells by promoting ATG4C expression and autophagy.Linking ER Stress to Autophagy: Potential Implications for Cancer Therapy.Caspase-1 participates in apoptosis of salivary glands in Rhipicephalus haemaphysaloides.Template-based protein-protein docking exploiting pairwise interfacial residue restraints.Correlation of altered expression of the autophagy marker LC3B with poor prognosis in astrocytoma.Synthetic substrates for measuring activity of autophagy proteases: autophagins (Atg4).High-throughput fluorescence assay for small-molecule inhibitors of autophagins/Atg4.CDK4/6 and autophagy inhibitors synergistically induce senescence in Rb positive cytoplasmic cyclin E negative cancers.Atg8-family interacting motif crucial for selective autophagy.A cryptic mitochondrial targeting motif in Atg4D links caspase cleavage with mitochondrial import and oxidative stress.Diagnostic and clinical relevance of the autophago-lysosomal network in human gliomasKinetics comparisons of mammalian Atg4 homologues indicate selective preferences toward diverse Atg8 substrates.Principles and current strategies for targeting autophagy for cancer treatment.Resilience of biochemical activity in protein domains in the face of structural divergence.The functional and pathologic relevance of autophagy proteases.Key autophagic targets and relevant small-molecule compounds in cancer therapy.The Xenopus laevis Atg4B Protease: Insights into Substrate Recognition and Application for Tag Removal from Proteins Expressed in Pro- and Eukaryotic Hosts.Mapping autophagy on to your metabolic radarDepletion of tissue factor suppresses hepatic metastasis and tumor growth in colorectal cancer via the downregulation of MMPs and the induction of autophagy and apoptosisPosttranslational modification of autophagy-related proteins in macroautophagyThe yeast autophagy protease Atg4 is regulated by thioredoxin.
P2860
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P2860
The structure of Atg4B-LC3 complex reveals the mechanism of LC3 processing and delipidation during autophagy
description
2009 nî lūn-bûn
@nan
2009 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
The structure of Atg4B-LC3 com ...... delipidation during autophagy
@ast
The structure of Atg4B-LC3 com ...... delipidation during autophagy
@en
The structure of Atg4B-LC3 com ...... delipidation during autophagy
@en-gb
The structure of Atg4B-LC3 com ...... delipidation during autophagy
@nl
type
label
The structure of Atg4B-LC3 com ...... delipidation during autophagy
@ast
The structure of Atg4B-LC3 com ...... delipidation during autophagy
@en
The structure of Atg4B-LC3 com ...... delipidation during autophagy
@en-gb
The structure of Atg4B-LC3 com ...... delipidation during autophagy
@nl
altLabel
The structure of Atg4B–LC3 com ...... delipidation during autophagy
@en
prefLabel
The structure of Atg4B-LC3 com ...... delipidation during autophagy
@ast
The structure of Atg4B-LC3 com ...... delipidation during autophagy
@en
The structure of Atg4B-LC3 com ...... delipidation during autophagy
@en-gb
The structure of Atg4B-LC3 com ...... delipidation during autophagy
@nl
P2093
P2860
P50
P3181
P356
P1433
P1476
The structure of Atg4B-LC3 com ...... delipidation during autophagy
@en
P2093
Hiroyuki Kumeta
Kenji Satoo
Yuko Fujioka
P2860
P304
P3181
P356
10.1038/EMBOJ.2009.80
P407
P577
2009-05-06T00:00:00Z