The epilepsy gene LGI1 encodes a secreted glycoprotein that binds to the cell surface
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Antibodies to Kv1 potassium channel-complex proteins leucine-rich, glioma inactivated 1 protein and contactin-associated protein-2 in limbic encephalitis, Morvan's syndrome and acquired neuromyotoniaLGI proteins in the nervous system.Glutamatergic neuron-targeted loss of LGI1 epilepsy gene results in seizuresKnockdown of zebrafish Lgi1a results in abnormal development, brain defects and a seizure-like behavioral phenotypeLoss of zebrafish lgi1b leads to hydrocephalus and sensitization to pentylenetetrazol induced seizure-like behavior.The temporal and spatial expression pattern of the LGI1 epilepsy predisposition gene during mouse embryonic cranial development.Electroclinical characterization of epileptic seizures in leucine-rich, glioma-inactivated 1-deficient mice.Altered language processing in autosomal dominant partial epilepsy with auditory featuresAdvances in Autoimmune Epilepsy Associated with Antibodies, Their Potential Pathogenic Molecular Mechanisms, and Current Recommended ImmunotherapiesInactivation of LGI1 expression accompanies early stage hyperplasia of prostate epithelium in the TRAMP murine model of prostate cancer.Reexpression of LGI1 in glioma cells results in dysregulation of genes implicated in the canonical axon guidance pathway.Similarity of molecular phenotype between known epilepsy gene LGI1 and disease candidate gene LGI2.Lgi1 null mutant mice exhibit myoclonic seizures and CA1 neuronal hyperexcitabilityA computational model of the LGI1 protein suggests a common binding site for ADAM proteins.Mutant LGI1 inhibits seizure-induced trafficking of Kv4.2 potassium channelsDomain-dependent clustering and genotype-phenotype analysis of LGI1 mutations in ADPEAFSecretion-Positive LGI1 Mutations Linked to Lateral Temporal Epilepsy Impair Binding to ADAM22 and ADAM23 ReceptorsGenetics of epilepsies.Arrested maturation of excitatory synapses in autosomal dominant lateral temporal lobe epilepsy.Homozygous inactivation of the LGI1 gene results in hypomyelination in the peripheral and central nervous systems.Epilepsy-aphasia syndromes.Genetics of epilepsy and relevance to current practice.Expanded phenotypes and outcomes among 256 LGI1/CASPR2-IgG-positive patients.LGI1-associated epilepsy through altered ADAM23-dependent neuronal morphologyChemical corrector treatment ameliorates increased seizure susceptibility in a mouse model of familial epilepsy.Homozygous Deletion of the LGI1 Gene in Mice Leads to Developmental Abnormalities Resulting in Cortical Dysplasia.Leucine-rich glioma inactivated 1 (Lgi1), an epilepsy-related secreted protein, has a nuclear localization signal and localizes to both the cytoplasm and the nucleus of the caudal ganglionic eminence neurons.FOS proliferating network construction in early colorectal cancer (CRC) based on integrative significant function cluster and inferring analysis.Neue serologische Marker zur Differentialdiagnose der Autoimmun-Enzephalitis/New serological markers for the differential diagnosis of autoimmune limbic encephalitis
P2860
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P2860
The epilepsy gene LGI1 encodes a secreted glycoprotein that binds to the cell surface
description
2006 nî lūn-bûn
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2006 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
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2006 թվականի դեկտեմբերին հրատարակված գիտական հոդված
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2006年の論文
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2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
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2006年論文
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2006年论文
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name
The epilepsy gene LGI1 encodes a secreted glycoprotein that binds to the cell surface
@ast
The epilepsy gene LGI1 encodes a secreted glycoprotein that binds to the cell surface
@en
The epilepsy gene LGI1 encodes a secreted glycoprotein that binds to the cell surface
@en-gb
The epilepsy gene LGI1 encodes a secreted glycoprotein that binds to the cell surface
@nl
type
label
The epilepsy gene LGI1 encodes a secreted glycoprotein that binds to the cell surface
@ast
The epilepsy gene LGI1 encodes a secreted glycoprotein that binds to the cell surface
@en
The epilepsy gene LGI1 encodes a secreted glycoprotein that binds to the cell surface
@en-gb
The epilepsy gene LGI1 encodes a secreted glycoprotein that binds to the cell surface
@nl
prefLabel
The epilepsy gene LGI1 encodes a secreted glycoprotein that binds to the cell surface
@ast
The epilepsy gene LGI1 encodes a secreted glycoprotein that binds to the cell surface
@en
The epilepsy gene LGI1 encodes a secreted glycoprotein that binds to the cell surface
@en-gb
The epilepsy gene LGI1 encodes a secreted glycoprotein that binds to the cell surface
@nl
P2093
P3181
P356
P1476
The epilepsy gene LGI1 encodes a secreted glycoprotein that binds to the cell surface
@en
P2093
Ana Ayerdi-Izquierdo
Jordi Pérez-Tur
José Manuel Morante-Redolat
Kristy Favell
Maria Salomé Sirerol-Piquer
Philip A Barker
Vicente Herranz-Pérez
P304
P3181
P356
10.1093/HMG/DDL421
P407
P577
2006-12-01T00:00:00Z