Human apolipoprotein E receptor 2. A novel lipoprotein receptor of the low density lipoprotein receptor family predominantly expressed in brain
about
Similarities and differences in structure, expression, and functions of VLDLR and ApoER2The generation and function of soluble apoE receptors in the CNSIdentification of a novel exon in apolipoprotein E receptor 2 leading to alternatively spliced mRNAs found in cells of the vascular wall but not in neuronal tissueReelin expression and glycosylation patterns are altered in Alzheimer's diseaseActivated protein C ligation of ApoER2 (LRP8) causes Dab1-dependent signaling in U937 cellsCrk and Crk-like play essential overlapping roles downstream of disabled-1 in the Reelin pathwayLipoprotein receptors and cholesterol in APP trafficking and proteolytic processing, implications for Alzheimer's diseaseProprotein convertase subtilisin/kexin type 9: from the discovery to the development of new therapies for cardiovascular diseasesExpression in vitro of alternatively spliced variants of the messenger RNA for human apolipoprotein E receptor-2 identified in human tissues by ribonuclease protection assaysCollagenase-3 binds to a specific receptor and requires the low density lipoprotein receptor-related protein for internalizationThe transmembrane domain and PXXP motifs of ApoE receptor 2 exclude it from carrying out clathrin-mediated endocytosisDifferential functions of members of the low density lipoprotein receptor family suggested by their distinct endocytosis ratesMolecular characterization of a novel human hybrid-type receptor that binds the alpha2-macroglobulin receptor-associated proteinCellular internalization and degradation of thrombospondin-1 is mediated by the amino-terminal heparin binding domain (HBD). High affinity interaction of dimeric HBD with the low density lipoprotein receptor-related proteinExon/intron organization, chromosome localization, alternative splicing, and transcription units of the human apolipoprotein E receptor 2 geneAnalysis of a two-domain binding site for the urokinase-type plasminogen activator-plasminogen activator inhibitor-1 complex in low-density-lipoprotein-receptor-related proteinThe reelin receptor ApoER2 recruits JNK-interacting proteins-1 and -2The low density lipoprotein receptor gene family. Differential expression of two alpha2-macroglobulin receptors in the brainUptake of lipoproteins for axonal growth of sympathetic neuronsAlternative splicing in the ligand binding domain of mouse ApoE receptor-2 produces receptor variants binding reelin but not alpha 2-macroglobulinExpression cloning and characterization of a novel glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein, GPI-HBP1Interaction of apolipoprotein J-amyloid beta-peptide complex with low density lipoprotein receptor-related protein-2/megalin. A mechanism to prevent pathological accumulation of amyloid beta-peptide.Differential splicing and glycosylation of Apoer2 alters synaptic plasticity and fear learningAdditive effect of LRP8/APOER2 R952Q variant to APOE epsilon2/epsilon3/epsilon4 genotype in modulating apolipoprotein E concentration and the risk of myocardial infarction: a case-control study.Potential Pathways for CNS Drug Delivery Across the Blood-Cerebrospinal Fluid BarrierLipoprotein receptors: new roles for ancient proteins.apoE3[K146N/R147W] acts as a dominant negative apoE form that prevents remnant clearance and inhibits the biogenesis of HDL.Lipoproteins in the central nervous system.Insights into synaptic function from mouse models of human cognitive disorders.Apolipoprotein E gene promoter polymorphisms in Alzheimer's disease.Astrocyte lipoproteins, effects of apoE on neuronal function, and role of apoE in amyloid-beta deposition in vivo.Apolipoprotein E receptor-2 deficiency enhances macrophage susceptibility to lipid accumulation and cell death to augment atherosclerotic plaque progression and necrosis.Genetic variants of ApoE and ApoER2 differentially modulate endothelial function.Molecular etiology of a dominant form of type III hyperlipoproteinemia caused by R142C substitution in apoE4More than cholesterol transporters: lipoprotein receptors in CNS function and neurodegenerationPolymorphism in maternal LRP8 gene is associated with fetal growthDomains of apoE4 required for the biogenesis of apoE-containing HDL.Yeast two-hybrid screen reveals novel protein interactions of the cytoplasmic tail of lipophorin receptor in silkworm brain.Selenium. Role of the essential metalloid in healthSorting nexin 17 regulates ApoER2 recycling and reelin signaling
P2860
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P2860
Human apolipoprotein E receptor 2. A novel lipoprotein receptor of the low density lipoprotein receptor family predominantly expressed in brain
description
1996 nî lūn-bûn
@nan
1996 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
name
Human apolipoprotein E recepto ...... edominantly expressed in brain
@ast
Human apolipoprotein E recepto ...... edominantly expressed in brain
@en
Human apolipoprotein E recepto ...... edominantly expressed in brain
@en-gb
Human apolipoprotein E recepto ...... edominantly expressed in brain
@nl
type
label
Human apolipoprotein E recepto ...... edominantly expressed in brain
@ast
Human apolipoprotein E recepto ...... edominantly expressed in brain
@en
Human apolipoprotein E recepto ...... edominantly expressed in brain
@en-gb
Human apolipoprotein E recepto ...... edominantly expressed in brain
@nl
prefLabel
Human apolipoprotein E recepto ...... edominantly expressed in brain
@ast
Human apolipoprotein E recepto ...... edominantly expressed in brain
@en
Human apolipoprotein E recepto ...... edominantly expressed in brain
@en-gb
Human apolipoprotein E recepto ...... edominantly expressed in brain
@nl
P2093
P921
P3181
P356
P1476
Human apolipoprotein E recepto ...... edominantly expressed in brain
@en
P2093
T Yamamoto
P304
P3181
P356
10.1074/JBC.271.14.8373
P407
P577
1996-04-05T00:00:00Z