Cloning of the cDNA and chromosome localization of the gene for human thymidine kinase 2
about
A deoxyribonucleotidase in mitochondria: involvement in regulation of dNTP pools and possible link to genetic diseaseHuman UMP-CMP kinase 2, a novel nucleoside monophosphate kinase localized in mitochondriaHuman deoxycytidine kinase is located in the cell nucleusMitochondrial diseases caused by toxic compound accumulation: from etiopathology to therapeutic approachesMitochondrial DNA depletion syndromes: review and updates of genetic basis, manifestations, and therapeutic optionsHuman mitochondrial 5'-deoxyribonucleotidase. Overproduction in cultured cells and functional aspectsFunctional expression of a multisubstrate deoxyribonucleoside kinase from Drosophila melanogaster and its C-terminal deletion mutantsFour deoxynucleoside kinase activities from Drosophila melanogaster are contained within a single monomeric enzyme, a new multifunctional deoxynucleoside kinaseNovel ribofuranosylnucleoside lead compounds for potent and selective inhibitors of mitochondrial thymidine kinase-2Cloning of mouse mitochondrial thymidine kinase 2 cDNACloning and characterization of mouse deoxyguanosine kinase. Evidence for a cytoplasmic isoformHuman thymidine kinase 2: molecular cloning and characterisation of the enzyme activity with antiviral and cytostatic nucleoside substratesCloning and characterization of full-length mouse thymidine kinase 2: the N-terminal sequence directs import of the precursor protein into mitochondria.Imaging of musculoskeletal bacterial infections by [124I]FIAU-PET/CTPreclinical aspects of lamivudine and famciclovir against hepatitis B virus.Regulation and functional contribution of thymidine kinase 1 in repair of DNA damageThymidine kinase in epithelial ovarian cancer: relationship with the other pyrimidine pathway enzymes.Onset and organ specificity of Tk2 deficiency depends on Tk1 down-regulation and transcriptional compensation.Mutagenesis of non-conserved active site residues improves the activity and narrows the specificity of human thymidine kinase 2Mitotic degradation of human thymidine kinase 1 is dependent on the anaphase-promoting complex/cyclosome-CDH1-mediated pathway.Origins of mitochondrial thymidine triphosphate: dynamic relations to cytosolic pools.Thymidine kinase and mtDNA depletion in human cardiomyopathy: epigenetic and translational evidence for energy starvation.Differential intracellular compartmentalization of herpetic thymidine kinases (TKs) in TK gene-transfected tumor cells: molecular characterization of the nuclear localization signal of herpes simplex virus type 1 TK.Retained sensitivity to cytotoxic pyrimidine nucleoside analogs in thymidine kinase 2 deficient human fibroblasts.Mitochondrial thymidine kinase and the enzymatic network regulating thymidine triphosphate pools in cultured human cells.Enhanced toxicity of purine nucleoside analogs in cells expressing Drosophila melanogaster nucleoside kinase mutants.Mitochondrial deoxynucleotide pools in quiescent fibroblasts: a possible model for mitochondrial neurogastrointestinal encephalomyopathy (MNGIE).Mitochondrial deoxyribonucleotides, pool sizes, synthesis, and regulation.Immunocytochemical detection of deoxycytidine kinase in haematological malignancies and solid tumours.Kinetic properties of mutant human thymidine kinase 2 suggest a mechanism for mitochondrial DNA depletion myopathy.The effect of a methyl or 2-fluoroethyl substituent at the N-3 position of thymidine, 3'-fluoro-3'-deoxythymidine and 1-beta-D-arabinosylthymine on their antiviral and cytostatic activity in cell culture.Cloning and characterization of the multisubstrate deoxyribonucleoside kinase of Drosophila melanogaster.
P2860
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P2860
Cloning of the cDNA and chromosome localization of the gene for human thymidine kinase 2
description
1997 nî lūn-bûn
@nan
1997 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի մարտին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Cloning of the cDNA and chromosome localization of the gene for human thymidine kinase 2
@ast
Cloning of the cDNA and chromosome localization of the gene for human thymidine kinase 2
@en
Cloning of the cDNA and chromosome localization of the gene for human thymidine kinase 2
@en-gb
Cloning of the cDNA and chromosome localization of the gene for human thymidine kinase 2
@nl
type
label
Cloning of the cDNA and chromosome localization of the gene for human thymidine kinase 2
@ast
Cloning of the cDNA and chromosome localization of the gene for human thymidine kinase 2
@en
Cloning of the cDNA and chromosome localization of the gene for human thymidine kinase 2
@en-gb
Cloning of the cDNA and chromosome localization of the gene for human thymidine kinase 2
@nl
prefLabel
Cloning of the cDNA and chromosome localization of the gene for human thymidine kinase 2
@ast
Cloning of the cDNA and chromosome localization of the gene for human thymidine kinase 2
@en
Cloning of the cDNA and chromosome localization of the gene for human thymidine kinase 2
@en-gb
Cloning of the cDNA and chromosome localization of the gene for human thymidine kinase 2
@nl
P2860
P356
P1476
Cloning of the cDNA and chromosome localization of the gene for human thymidine kinase 2
@en
P2093
M Johansson
P2860
P304
P356
10.1074/JBC.272.13.8454
P407
P577
1997-03-01T00:00:00Z