Cloning and functional expression of a human liver organic cation transporter
about
Expression and pharmacological profile of the human organic cation transporters hOCT1, hOCT2 and hOCT3Evolutionary conservation predicts function of variants of the human organic cation transporter, OCT1The X-linked lymphoproliferative syndrome gene product SH2D1A associates with p62dok (Dok1) and activates NF-kappa BOATPs, OATs and OCTs: the organic anion and cation transporters of the SLCO and SLC22A gene superfamiliesRole of the plasma membrane transporter of organic cations OCT1 and its genetic variants in modern liver pharmacologyHepatocyte nuclear factor 1 regulates the expression of the organic cation transporter 1 via binding to an evolutionary conserved region in intron 1 of the OCT1 genePharmacogenetics meets metabolomics: discovery of tryptophan as a new endogenous OCT2 substrate related to metformin dispositionTransport mechanisms and their pathology-induced regulation govern tyrosine kinase inhibitor delivery in rheumatoid arthritisMembrane transporters as mediators of Cisplatin effects and side effects.Expression and analysis of two novel rat organic cation transporter homologs, SLC22A17 and SLC22A23.Organic anion and cation transporter expression and function during embryonic kidney development and in organ culture modelsXenobiotic, bile acid, and cholesterol transporters: function and regulation.Genetic polymorphisms and haplotypes of the organic cation transporter 1 gene (SLC22A1) in the Xhosa population of South AfricaOCT1 genetic variants influence the pharmacokinetics of morphine in children.Pharmacogenetics of Anti-Diabetes Drugs.Effect of genetic variation in the organic cation transporter 1, OCT1, on metformin pharmacokinetics.OCT1 Expression in adipocytes could contribute to increased metformin action in obese subjects.Hepatocellular transport proteins and their role in liver disease.Role of organic cation transporter 1, OCT1 in the pharmacokinetics and toxicity of cis-diammine(pyridine)chloroplatinum(II) and oxaliplatin in mice.Pharmacogenetics in drug regulation: promise, potential and pitfalls.Effect of genetic variation in the organic cation transporter 1 (OCT1) on metformin actionDrug Transporters and Na+/H+ Exchange Regulatory Factor PSD-95/Drosophila Discs Large/ZO-1 ProteinsGlobal genetic analyses reveal strong inter-ethnic variability in the loss of activity of the organic cation transporter OCT1.Pharmacophore modelling of stereoselective binding to the human organic cation transporter (hOCT1).Sorafenib hepatobiliary disposition: mechanisms of hepatic uptake and disposition of generated metabolites.The role of transporters in the toxicity of nucleoside and nucleotide analogs.Inhibition of lung tumorigenesis by metformin is associated with decreased plasma IGF-I and diminished receptor tyrosine kinase signaling.Organic cation transporters are determinants of oxaliplatin cytotoxicity.The drug transporter-metabolism alliance: uncovering and defining the interplay.Pharmacogenomic implications of the evolutionary history of infectious diseases in AfricaPolyspecific organic cation transporters and their impact on drug intracellular levels and pharmacodynamics.Transport and metabolism of radiolabeled choline in hepatocellular carcinoma.Epithelial organic cation transporters ensure pH-dependent drug absorption in the airway.Involvement of organic cation transporter-3 and plasma membrane monoamine transporter in serotonin uptake in human brain vascular smooth muscle cells.OCT1 in hepatic steatosis and thiamine disposition.Functional identification of organic cation transporter 1 as an atenolol transporter sensitive to flavonoids.Hexokinase-2 depletion inhibits glycolysis and induces oxidative phosphorylation in hepatocellular carcinoma and sensitizes to metformin.Metformin Inhibits Hepatic mTORC1 Signaling via Dose-Dependent Mechanisms Involving AMPK and the TSC Complex.Metformin and Autoimmunity: A "New Deal" of an Old Drug.
P2860
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P2860
Cloning and functional expression of a human liver organic cation transporter
description
1997 nî lūn-bûn
@nan
1997 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Cloning and functional expression of a human liver organic cation transporter
@ast
Cloning and functional expression of a human liver organic cation transporter
@en
Cloning and functional expression of a human liver organic cation transporter
@en-gb
Cloning and functional expression of a human liver organic cation transporter
@nl
type
label
Cloning and functional expression of a human liver organic cation transporter
@ast
Cloning and functional expression of a human liver organic cation transporter
@en
Cloning and functional expression of a human liver organic cation transporter
@en-gb
Cloning and functional expression of a human liver organic cation transporter
@nl
prefLabel
Cloning and functional expression of a human liver organic cation transporter
@ast
Cloning and functional expression of a human liver organic cation transporter
@en
Cloning and functional expression of a human liver organic cation transporter
@en-gb
Cloning and functional expression of a human liver organic cation transporter
@nl
P2093
P1476
Cloning and functional expression of a human liver organic cation transporter
@en
P2093
P304
P407
P577
1997-06-01T00:00:00Z