Acetylation of conserved lysines in the catalytic core of cyclin-dependent kinase 9 inhibits kinase activity and regulates transcription
about
An overview of Cdk1-controlled targets and processesAcetylation of cyclin T1 regulates the equilibrium between active and inactive P-TEFb in cellsThe multifaceted role of lysine acetylation in cancer: prognostic biomarker and therapeutic targetManipulation of the host protein acetylation network by human immunodeficiency virus type 1Epigenetic and Posttranslational Modifications in Light Signal Transduction and the Circadian Clock in Neurospora crassaEvolution and functional cross-talk of protein post-translational modificationsLysine acetylation targets protein complexes and co-regulates major cellular functionsThe transcriptional co-activator PCAF regulates cdk2 activityFunctional characterization of a new member of the Cdk9 family in Aspergillus nidulans.Discernment of possible mechanisms of hepatotoxicity via biological processes over-represented by co-expressed genesAcute hypoxia affects P-TEFb through HDAC3 and HEXIM1-dependent mechanism to promote gene-specific transcriptional repression.Structural basis for phosphorylation and lysine acetylation cross-talk in a kinase motif associated with myocardial ischemia and cardioprotectionAcetylation of a conserved lysine residue in the ATP binding pocket of p38 augments its kinase activity during hypertrophy of cardiomyocytesCLP-1 associates with MyoD and HDAC to restore skeletal muscle cell regeneration.Gcn5 and PCAF regulate PPARĪ³ and Prdm16 expression to facilitate brown adipogenesisSelective histonedeacetylase inhibitor M344 intervenes in HIV-1 latency through increasing histone acetylation and activation of NF-kappaBExpanding role of cyclin dependent kinases in cytokine inducible gene expression.Emerging roles of post-translational modifications in signal transduction and angiogenesisSIRT2 directs the replication stress response through CDK9 deacetylation.P-TEFb- the final frontier.KAT2A/KAT2B-targeted acetylome reveals a role for PLK4 acetylation in preventing centrosome amplification.Characterization of Cdk9 T-loop phosphorylation in resting and activated CD4(+) T lymphocytes.Novel HIV-1 therapeutics through targeting altered host cell pathways.Chromatin dynamics associated with HIV-1 Tat-activated transcription.Curing HIV: Pharmacologic approaches to target HIV-1 latency.A kinase-independent activity of Cdk9 modulates glucocorticoid receptor-mediated gene induction.CYCLINg through transcription: posttranslational modifications of P-TEFb regulate transcription elongation.Functional analysis of proteins and protein species using shotgun proteomics and linear mathematics.Novel electrostatic mechanism for mode of action by N-acetylated proteins: cell signaling and phosphorylation.Lost in transcription: molecular mechanisms that control HIV latencyMaking a Short Story Long: Regulation of P-TEFb and HIV-1 Transcriptional Elongation in CD4+ T Lymphocytes and Macrophages.Characterization of human neural differentiation from pluripotent stem cells using proteomics/PTMomics--current state-of-the-art and challenges.SIRT7-dependent deacetylation of CDK9 activates RNA polymerase II transcriptionp27Kip1, PCAF and PAX5 cooperate in the transcriptional regulation of specific target genes.Connecting HIV-1 integration and transcription: a step toward new treatments.The emerging picture of CDK9/P-TEFb: more than 20 years of advances since PITALRE.Nuclear landscape of HIV-1 infection and integration.Computer-aided design, synthesis and validation of 2-phenylquinazolinone fragments as CDK9 inhibitors with anti-HIV-1 Tat-mediated transcription activity.Mitotic phosphotyrosine network analysis reveals that tyrosine phosphorylation regulates Polo-like kinase 1 (PLK1).Molecular Understanding of HIV-1 Latency.
P2860
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P2860
Acetylation of conserved lysines in the catalytic core of cyclin-dependent kinase 9 inhibits kinase activity and regulates transcription
description
2008 nĆ® lÅ«n-bĆ»n
@nan
2008 Õ©ÕøÖÕ”ÕÆÕ”Õ¶Õ« Ō±ÕŗÖÕ«Õ¬Õ«Õ¶ Õ°ÖÕ”ÕæÕ”ÖÕ”ÕÆÕøÖÕ”Õ® Õ£Õ«ÕæÕ”ÕÆÕ”Õ¶ ÕµÖ
Õ¤ÕøÖÕ”Õ®
@hyw
2008 Õ©Õ¾Õ”ÕÆÕ”Õ¶Õ« Õ”ÕŗÖÕ«Õ¬Õ«Õ¶ Õ°ÖÕ”ÕæÕ”ÖÕ”ÕÆÕ¾Õ”Õ® Õ£Õ«ÕæÕ”ÕÆÕ”Õ¶ Õ°ÕøÕ¤Õ¾Õ”Õ®
@hy
2008幓ć®č«ę
@ja
2008幓č«ę
@yue
2008幓č«ę
@zh-hant
2008幓č«ę
@zh-hk
2008幓č«ę
@zh-mo
2008幓č«ę
@zh-tw
2008幓č®ŗę
@wuu
name
Acetylation of conserved lysin ...... ty and regulates transcription
@ast
Acetylation of conserved lysin ...... ty and regulates transcription
@en
Acetylation of conserved lysin ...... ty and regulates transcription
@en-gb
Acetylation of conserved lysin ...... ty and regulates transcription
@nl
type
label
Acetylation of conserved lysin ...... ty and regulates transcription
@ast
Acetylation of conserved lysin ...... ty and regulates transcription
@en
Acetylation of conserved lysin ...... ty and regulates transcription
@en-gb
Acetylation of conserved lysin ...... ty and regulates transcription
@nl
prefLabel
Acetylation of conserved lysin ...... ty and regulates transcription
@ast
Acetylation of conserved lysin ...... ty and regulates transcription
@en
Acetylation of conserved lysin ...... ty and regulates transcription
@en-gb
Acetylation of conserved lysin ...... ty and regulates transcription
@nl
P2860
P50
P3181
P356
P1476
Acetylation of conserved lysin ...... ty and regulates transcription
@en
P2093
Anna Cereseto
P2860
P304
P3181
P356
10.1128/MCB.01557-07
P407
P577
2008-02-04T00:00:00Z