Organization of the gene for human platelet/endothelial cell adhesion molecule-1 shows alternatively spliced isoforms and a functionally complex cytoplasmic domain
about
Integrin engagement mediates tyrosine dephosphorylation on platelet-endothelial cell adhesion molecule 1.Tyrosine residue in exon 14 of the cytoplasmic domain of platelet endothelial cell adhesion molecule-1 (PECAM-1/CD31) regulates ligand binding specificityCD31/PECAM-1 is a ligand for alpha v beta 3 integrin involved in adhesion of leukocytes to endotheliumSwitched at birth: a new family for PECAM-1.Lactosylceramide recruits PKCalpha/epsilon and phospholipase A2 to stimulate PECAM-1 expression in human monocytes and adhesion to endothelial cells.PECAM-1: conflicts of interest in inflammation.The alleles of PECAM-1.Leucine125Valine (Leu125Val) Gene Polymorphism of Platelet Endothelial Cell Adhesion Molecule-1 (PECAM-1) and Myocardial Infarction in Indian PopulationPECAM-1 regulates proangiogenic properties of endothelial cells through modulation of cell-cell and cell-matrix interactionsPECAM-1/CD31 trans-homophilic binding at the intercellular junctions is independent of its cytoplasmic domain; evidence for heterophilic interaction with integrin alphavbeta3 in CisPECAM-1 isoforms, eNOS and endoglin axis in regulation of angiogenesisPECAM-1 isoform-specific functions in PECAM-1-deficient brain microvascular endothelial cells.An alternatively spliced isoform of PECAM-1 is expressed at high levels in human and murine tissues, and suggests a novel role for the C-terminus of PECAM-1 in cytoprotective signaling.The biology of PECAM-1.PECAM-1: regulator of endothelial junctional integrity.Interaction of CD31 with a heterophilic counterreceptor involved in downregulation of human T cell responses.Down-regulation of platelet endothelial cell adhesion molecule-1 results in thrombospondin-1 expression and concerted regulation of endothelial cell phenotype.Thrombospondin-1, a natural inhibitor of angiogenesis, regulates platelet-endothelial cell adhesion molecule-1 expression and endothelial cell morphogenesis.Endothelial cell regulation of leukocyte infiltration in inflammatory tissues.Platelet Endothelial Cell Adhesion Molecule-1 and Oligodendrogenesis: Significance in Alcohol Use Disorders.CRISPR-mediated deletion of the PECAM-1 cytoplasmic domain increases receptor lateral mobility and strengthens endothelial cell junctional integrity.
P2860
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P2860
Organization of the gene for human platelet/endothelial cell adhesion molecule-1 shows alternatively spliced isoforms and a functionally complex cytoplasmic domain
description
1994 nî lūn-bûn
@nan
1994 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
name
Organization of the gene for h ...... lly complex cytoplasmic domain
@ast
Organization of the gene for h ...... lly complex cytoplasmic domain
@en
Organization of the gene for h ...... lly complex cytoplasmic domain
@en-gb
Organization of the gene for h ...... lly complex cytoplasmic domain
@nl
type
label
Organization of the gene for h ...... lly complex cytoplasmic domain
@ast
Organization of the gene for h ...... lly complex cytoplasmic domain
@en
Organization of the gene for h ...... lly complex cytoplasmic domain
@en-gb
Organization of the gene for h ...... lly complex cytoplasmic domain
@nl
prefLabel
Organization of the gene for h ...... lly complex cytoplasmic domain
@ast
Organization of the gene for h ...... lly complex cytoplasmic domain
@en
Organization of the gene for h ...... lly complex cytoplasmic domain
@en-gb
Organization of the gene for h ...... lly complex cytoplasmic domain
@nl
P2093
P1433
P1476
Organization of the gene for h ...... lly complex cytoplasmic domain
@en
P2093
N E Kirschbaum
P J Newman
R J Gumina
P304
P407
P577
1994-12-15T00:00:00Z