TCF-4 mediates cell type-specific regulation of proglucagon gene expression by beta-catenin and glycogen synthase kinase-3beta
about
Glucagon-like peptide-1 activation of TCF7L2-dependent Wnt signaling enhances pancreatic beta cell proliferationDecreased TCF7L2 protein levels in type 2 diabetes mellitus correlate with downregulation of GIP- and GLP-1 receptors and impaired beta-cell functionAssociation of the TCF7L2 polymorphism with colorectal cancer and adenoma riskThe association between the rs11196218A/G polymorphism of the TCF7L2 gene and type 2 diabetes in the Chinese Han population: a meta-analysisNew insight into the mechanisms underlying the function of the incretin hormone glucagon-like peptide-1 in pancreatic β-cells: the involvement of the Wnt signaling pathway effector β-cateninAntidiabetic Effect of Galantamine: Novel Effect for a Known Centrally Acting DrugCurcumin prevents high fat diet induced insulin resistance and obesity via attenuating lipogenesis in liver and inflammatory pathway in adipocytesUsing gene-network landscape to dissect genotype effects of TCF7L2 genetic variant on diabetes and cardiovascular riskFrom estrogen-centric to aging and oxidative stress: a revised perspective of the pathogenesis of osteoporosisWnt signaling regulates mitochondrial physiology and insulin sensitivityThe p53 transcriptional target gene wnt7b contributes to NGF-inducible neurite outgrowth in neuronal PC12 cellsTCF7L2 modulates glucose homeostasis by regulating CREB- and FoxO1-dependent transcriptional pathway in the liverPharmacogenomics in type 2 diabetes: oral antidiabetic drugs.Pharmacogenomics of Drug Response in Type 2 Diabetes: Toward the Definition of Tailored Therapies?Association of fibrillin-3 and transcription factor-7-like 2 gene variants with metabolic phenotypes in PCOS.TCF7L2 gene polymorphisms do not predict susceptibility to diabetes in tropical calcific pancreatitis but may interact with SPINK1 and CTSB mutations in predicting diabetes.The TCF7L2 locus and type 1 diabetesWeak or no association of TCF7L2 variants with Type 2 diabetes risk in an Arab population.Association between TCF7L2 gene polymorphisms and susceptibility to type 2 diabetes mellitus: a large Human Genome Epidemiology (HuGE) review and meta-analysisIdentification of novel transcriptional regulators involved in macrophage differentiation and activation in U937 cells.Large effects on body mass index and insulin resistance of fat mass and obesity associated gene (FTO) variants in patients with polycystic ovary syndrome (PCOS).TCF7L2 variant rs7903146 affects the risk of type 2 diabetes by modulating incretin action.Puerarin Protects Pancreatic β-Cells in Obese Diabetic Mice via Activation of GLP-1R SignalingPolymorphisms of TCF7L2 and HHEX genes in Chinese women with polycystic ovary syndromeKCNJ11, ABCC8 and TCF7L2 polymorphisms and the response to sulfonylurea treatment in patients with type 2 diabetes: a bioinformatics assessment.Genome-wide association studies: progress and potential for drug discovery and development.Impact of common variants of PPARG, KCNJ11, TCF7L2, SLC30A8, HHEX, CDKN2A, IGF2BP2, and CDKAL1 on the risk of type 2 diabetes in 5,164 Indians.CREB and FoxO1: two transcription factors for the regulation of hepatic gluconeogenesisGenetics talks to epigenetics? The interplay between sequence variants and chromatin structureExpression of the diabetes-associated gene TCF7L2 in adult mouse brainAn in vivo cis-regulatory screen at the type 2 diabetes associated TCF7L2 locus identifies multiple tissue-specific enhancers.Potential role of TCF7L2 gene variants on cardiac sympathetic/parasympathetic activityResequencing and analysis of variation in the TCF7L2 gene in African Americans suggests that SNP rs7903146 is the causal diabetes susceptibility variant.Meta-analysis of associations between TCF7L2 polymorphisms and risk of type 2 diabetes mellitus in the Chinese population.Replication of type 2 diabetes candidate genes variations in three geographically unrelated Indian population groups.Association of TCF7L2 gene polymorphisms with T2DM in the population of Hyderabad, India.Carriers of a novel frame-shift insertion in WNT16a possess elevated pancreatic expression of TCF7L2.The emerging genetic architecture of type 2 diabetesThe role of incretins in glucose homeostasis and diabetes treatment.Association of TCF7L2 allelic variations with gastric function, satiation, and GLP-1 levels.
P2860
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P2860
TCF-4 mediates cell type-specific regulation of proglucagon gene expression by beta-catenin and glycogen synthase kinase-3beta
description
2005 nî lūn-bûn
@nan
2005 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
TCF-4 mediates cell type-speci ...... glycogen synthase kinase-3beta
@ast
TCF-4 mediates cell type-speci ...... glycogen synthase kinase-3beta
@en
TCF-4 mediates cell type-speci ...... glycogen synthase kinase-3beta
@en-gb
TCF-4 mediates cell type-speci ...... glycogen synthase kinase-3beta
@nl
type
label
TCF-4 mediates cell type-speci ...... glycogen synthase kinase-3beta
@ast
TCF-4 mediates cell type-speci ...... glycogen synthase kinase-3beta
@en
TCF-4 mediates cell type-speci ...... glycogen synthase kinase-3beta
@en-gb
TCF-4 mediates cell type-speci ...... glycogen synthase kinase-3beta
@nl
prefLabel
TCF-4 mediates cell type-speci ...... glycogen synthase kinase-3beta
@ast
TCF-4 mediates cell type-speci ...... glycogen synthase kinase-3beta
@en
TCF-4 mediates cell type-speci ...... glycogen synthase kinase-3beta
@en-gb
TCF-4 mediates cell type-speci ...... glycogen synthase kinase-3beta
@nl
P2093
P2860
P3181
P356
P1476
TCF-4 mediates cell type-speci ...... glycogen synthase kinase-3beta
@en
P2093
Fenghua Yi
Patricia L Brubaker
Tianru Jin
P2860
P304
P3181
P356
10.1074/JBC.M411487200
P407
P577
2005-01-14T00:00:00Z