A core complex of BBS proteins cooperates with the GTPase Rab8 to promote ciliary membrane biogenesis
about
The Golgin GMAP210/TRIP11 anchors IFT20 to the Golgi complexThe dynamic cilium in human diseasesA role for prenylated rab acceptor 1 in vertebrate photoreceptor developmentA complex of BBS1 and NPHP7 is required for cilia motility in zebrafishCiliogenesis is regulated by a huntingtin-HAP1-PCM1 pathway and is altered in Huntington diseaseBBS6, BBS10, and BBS12 form a complex with CCT/TRiC family chaperonins and mediate BBSome assemblyPrimary ciliogenesis requires the distal appendage component Cep123.A novel protein LZTFL1 regulates ciliary trafficking of the BBSome and SmoothenedCep164, a novel centriole appendage protein required for primary cilium formationBardet-Biedl syndrome 3 (Bbs3) knockout mouse model reveals common BBS-associated phenotypes and Bbs3 unique phenotypesTMEM237 is mutated in individuals with a Joubert syndrome related disorder and expands the role of the TMEM family at the ciliary transition zoneBardet-Biedl syndrome proteins 1 and 3 regulate the ciliary trafficking of polycystic kidney disease 1 proteinCharacterization of CCDC28B reveals its role in ciliogenesis and provides insight to understand its modifier effect on Bardet-Biedl syndromeCentriolar association of ALMS1 and likely centrosomal functions of the ALMS motif-containing proteins C10orf90 and KIAA1731The oral-facial-digital syndrome gene C2CD3 encodes a positive regulator of centriole elongation.The Lowe syndrome protein OCRL1 is involved in primary cilia assemblyBBS proteins interact genetically with the IFT pathway to influence SHH-related phenotypesTULP3 bridges the IFT-A complex and membrane phosphoinositides to promote trafficking of G protein-coupled receptors into primary ciliaBardet-Biedl syndrome-associated small GTPase ARL6 (BBS3) functions at or near the ciliary gate and modulates Wnt signalingMapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathwaysCEP90 is required for the assembly and centrosomal accumulation of centriolar satellites, which is essential for primary cilia formationFamily-wide characterization of the DENN domain Rab GDP-GTP exchange factorsNephrocystins and MKS proteins interact with IFT particle and facilitate transport of selected ciliary cargosDirect role of Bardet-Biedl syndrome proteins in transcriptional regulationOverexpression of optineurin E50K disrupts Rab8 interaction and leads to a progressive retinal degeneration in miceFunctional genomic screen for modulators of ciliogenesis and cilium lengthThe intraflagellar transport protein IFT27 promotes BBSome exit from cilia through the GTPase ARL6/BBS3.Combining Cep290 and Mkks ciliopathy alleles in mice rescues sensory defects and restores ciliogenesisRecruitment of PCM1 to the centrosome by the cooperative action of DISC1 and BBS4: a candidate for psychiatric illnessesCEP290 interacts with the centriolar satellite component PCM-1 and is required for Rab8 localization to the primary ciliumRab13 regulates membrane trafficking between TGN and recycling endosomes in polarized epithelial cells.Intrinsic protein-protein interaction-mediated and chaperonin-assisted sequential assembly of stable bardet-biedl syndrome protein complex, the BBSomeTRIM32 is an E3 ubiquitin ligase for dysbindinThe novel centriolar satellite protein SSX2IP targets Cep290 to the ciliary transition zoneNegative regulation of ciliary length by ciliary male germ cell-associated kinase (Mak) is required for retinal photoreceptor survivalThe Talpid3 gene (KIAA0586) encodes a centrosomal protein that is essential for primary cilia formationTOPORS, implicated in retinal degeneration, is a cilia-centrosomal proteinHIF1α deubiquitination by USP8 is essential for ciliogenesis in normoxiaMotile cilia of human airway epithelia are chemosensoryBBS mutations modify phenotypic expression of CEP290-related ciliopathies
P2860
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P248
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P2860
A core complex of BBS proteins cooperates with the GTPase Rab8 to promote ciliary membrane biogenesis
description
2007 nî lūn-bûn
@nan
2007 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
A core complex of BBS proteins ...... te ciliary membrane biogenesis
@ast
A core complex of BBS proteins ...... te ciliary membrane biogenesis
@en
A core complex of BBS proteins ...... te ciliary membrane biogenesis
@en-gb
A core complex of BBS proteins ...... te ciliary membrane biogenesis
@nl
type
label
A core complex of BBS proteins ...... te ciliary membrane biogenesis
@ast
A core complex of BBS proteins ...... te ciliary membrane biogenesis
@en
A core complex of BBS proteins ...... te ciliary membrane biogenesis
@en-gb
A core complex of BBS proteins ...... te ciliary membrane biogenesis
@nl
prefLabel
A core complex of BBS proteins ...... te ciliary membrane biogenesis
@ast
A core complex of BBS proteins ...... te ciliary membrane biogenesis
@en
A core complex of BBS proteins ...... te ciliary membrane biogenesis
@en-gb
A core complex of BBS proteins ...... te ciliary membrane biogenesis
@nl
P2093
P50
P921
P3181
P1433
P1476
A core complex of BBS proteins ...... te ciliary membrane biogenesis
@en
P2093
Alexander V Loktev
Andreas Merdes
Christopher J Westlake
J Fernando Bazan
Johan Peränen
Peter K Jackson
Qihong Zhang
Richard H Scheller
P304
P3181
P356
10.1016/J.CELL.2007.03.053
P407
P577
2007-06-01T00:00:00Z