Plakophilin 2: a critical scaffold for PKC alpha that regulates intercellular junction assembly
about
E-cadherin and plakoglobin recruit plakophilin3 to the cell border to initiate desmosome assemblyDisease mutations in desmoplakin inhibit Cx43 membrane targeting mediated by desmoplakin-EB1 interactions.Mutated desmoglein-2 proteins are incorporated into desmosomes and exhibit dominant-negative effects in arrhythmogenic right ventricular cardiomyopathyThe desmosomeDesmosome regulation and signaling in diseaseStratifin (14-3-3 σ) limits plakophilin-3 exchange with the desmosomal plaqueDesmosomes and the sodium channel complex: implications for arrhythmogenic cardiomyopathy and Brugada syndromeInteractions between ankyrin-G, Plakophilin-2, and Connexin43 at the cardiac intercalated discArrhythmogenic right ventricular cardiomyopathy plakophilin-2 mutations disrupt desmosome assembly and stabilityPlakophilins: multifunctional scaffolds for adhesion and signalingPlakophilin 2 couples actomyosin remodeling to desmosomal plaque assembly via RhoA.Mechanistic basis of desmosome-targeted diseasesPlakophilin-3 catenin associates with the ETV1/ER81 transcription factor to positively modulate gene activityOrdered assembly of the adhesive and electrochemical connections within newly formed intercalated disks in primary cultures of adult rat cardiomyocytesSerine 34 phosphorylation of rho guanine dissociation inhibitor (RhoGDIalpha) links signaling from conventional protein kinase C to RhoGTPase in cell adhesion.Plakophilins 1 and 3 bind to FXR1 and thereby influence the mRNA stability of desmosomal proteinsGSK3- and PRMT-1-dependent modifications of desmoplakin control desmoplakin-cytoskeleton dynamics.Keratins control intercellular adhesion involving PKC-α-mediated desmoplakin phosphorylation.Plakophilin 2 affects cell migration by modulating focal adhesion dynamics and integrin protein expression.Plakophilin 3 mediates Rap1-dependent desmosome assembly and adherens junction maturation.Sertoli-germ cell junctions in the testis: a review of recent dataAdducin is required for desmosomal cohesion in keratinocytes.Desmosomal plakophilins in the prostate and prostatic adenocarcinomas: implications for diagnosis and tumor progression.PDGF receptor activation induces p120-catenin phosphorylation at serine 879 via a PKCalpha-dependent pathway.Synergy analysis reveals association between insulin signaling and desmoplakin expression in palmitate treated HepG2 cellsThe biology of the desmosome-like junction a versatile anchoring junction and signal transducer in the seminiferous epithelium.Plakoglobin rescues adhesive defects induced by ectodomain truncation of the desmosomal cadherin desmoglein 1: implications for exfoliative toxin-mediated skin blistering.Desmosome assembly and dynamicsThe desmosomal armadillo protein plakoglobin regulates prostate cancer cell adhesion and motility through vitronectin-dependent Src signalingDesmosomes: regulators of cellular signaling and adhesion in epidermal health and disease.Desmocollin‑2 affects the adhesive strength and cytoskeletal arrangement in esophageal squamous cell carcinoma cellsThe calcium ATPase SERCA2 regulates desmoplakin dynamics and intercellular adhesive strength through modulation of PKCα signaling.Activation of the δ-opioid receptor promotes cutaneous wound healing by affecting keratinocyte intercellular adhesion and migrationStructure, function, and regulation of desmosomes.Cardiac phosphoproteomics during remote ischemic preconditioning: a role for the sarcomeric Z-disk proteinsThe extent of desmoglein 3 depletion in pemphigus vulgaris is dependent on Ca(2+)-induced differentiation: a role in suprabasal epidermal skin splitting?Type I keratin 17 protein is phosphorylated on serine 44 by p90 ribosomal protein S6 kinase 1 (RSK1) in a growth- and stress-dependent fashion.Desmosomal cadherins utilize distinct kinesins for assembly into desmosomes.Multiple regulatory variants located in cell type-specific enhancers within the PKP2 locus form major risk and protective haplotypes for canine atopic dermatitis in German shepherd dogs.Plakophilin-2 loss promotes TGF-β1/p38 MAPK-dependent fibrotic gene expression in cardiomyocytes.
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P2860
Plakophilin 2: a critical scaffold for PKC alpha that regulates intercellular junction assembly
description
2008 nî lūn-bûn
@nan
2008 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Plakophilin 2: a critical scaf ...... ntercellular junction assembly
@ast
Plakophilin 2: a critical scaf ...... ntercellular junction assembly
@en
Plakophilin 2: a critical scaf ...... ntercellular junction assembly
@en-gb
Plakophilin 2: a critical scaf ...... ntercellular junction assembly
@nl
type
label
Plakophilin 2: a critical scaf ...... ntercellular junction assembly
@ast
Plakophilin 2: a critical scaf ...... ntercellular junction assembly
@en
Plakophilin 2: a critical scaf ...... ntercellular junction assembly
@en-gb
Plakophilin 2: a critical scaf ...... ntercellular junction assembly
@nl
prefLabel
Plakophilin 2: a critical scaf ...... ntercellular junction assembly
@ast
Plakophilin 2: a critical scaf ...... ntercellular junction assembly
@en
Plakophilin 2: a critical scaf ...... ntercellular junction assembly
@en-gb
Plakophilin 2: a critical scaf ...... ntercellular junction assembly
@nl
P2093
P2860
P921
P356
P1476
Plakophilin 2: a critical scaf ...... ntercellular junction assembly
@en
P2093
Amanda E Bass-Zubek
Evangeline V Amargo
James K Wahl
Kathleen J Green
Mitchell F Denning
Nicholas J Garcia
Ryan P Hobbs
Sherry N Hsieh
Xinyu Chen
P2860
P304
P356
10.1083/JCB.200712133
P407
P577
2008-05-12T00:00:00Z