Caspase cleavage of tau: linking amyloid and neurofibrillary tangles in Alzheimer's disease
about
Histone deacetylase 6 interacts with the microtubule-associated protein tauClathrin adaptor CALM/PICALM is associated with neurofibrillary tangles and is cleaved in Alzheimer's brainsA duplicated motif controls assembly of zona pellucida domain proteinsCaspase-1 inhibitors from an extremophilic fungus that target specific leukemia cell linesAccumulation of transactive response DNA binding protein 43 in mild cognitive impairment and Alzheimer diseaseBile acids: regulation of apoptosis by ursodeoxycholic acidTau fragmentation, aggregation and clearance: the dual role of lysosomal processingModeling Alzheimer's Disease with Induced Pluripotent Stem Cells: Current Challenges and Future ConcernsTau clearance mechanisms and their possible role in the pathogenesis of Alzheimer diseaseThe role of tau in neurodegenerative diseases and its potential as a therapeutic targetInteractions between mitochondria and the transcription factor myocyte enhancer factor 2 (MEF2) regulate neuronal structural and functional plasticity and metaplasticityTau and tauopathiesMetformin promotes tau aggregation and exacerbates abnormal behavior in a mouse model of tauopathyLysosomal dysfunction promotes cleavage and neurotoxicity of tau in vivoBlood biomarkers for brain injury: What are we measuring?Tau Biology and Tau-Directed Therapies for Alzheimer's DiseaseAutophagy in neurodegenerative diseases: from mechanism to therapeutic approachMultiple signaling factors and drugs alleviate neuronal death induced by expression of human and zebrafish tau proteins in vivoThe release and trans-synaptic transmission of Tau via exosomesStructural polymorphism of 441-residue tau at single residue resolutionDynamic role of postsynaptic caspase-3 and BIRC4 in zebra finch song-response habituationCytoskeletal pathologies of Alzheimer diseaseCaspase-3 activation as a bifurcation point between plasticity and cell death.Mice lacking caspase-2 are protected from behavioral changes, but not pathology, in the YAC128 model of Huntington disease.Early axonopathy preceding neurofibrillary tangles in mutant tau transgenic mice.The amino terminus of tau inhibits kinesin-dependent axonal transport: implications for filament toxicity.β-Amyloid impairs axonal BDNF retrograde trafficking.Caspase-cleavage of tau is an early event in Alzheimer disease tangle pathologyCo-expression of truncated and full-length tau induces severe neurotoxicityGlial contributions to neurodegeneration in tauopathies.AGGRESCAN: a server for the prediction and evaluation of "hot spots" of aggregation in polypeptides.Conformational changes and cleavage of tau in Pick bodies parallel the early processing of tau found in Alzheimer pathology.Low density lipoprotein receptor-related protein 1 promotes anti-apoptotic signaling in neurons by activating Akt survival pathway.Roles of tau protein in health and disease.Potential mechanisms linking cholesterol to Alzheimer's disease-like pathology in rabbit brain, hippocampal organotypic slices, and skeletal muscleLoss of MAP function leads to hippocampal synapse loss and deficits in the Morris Water Maze with agingHumanized monoclonal antibody armanezumab specific to N-terminus of pathological tau: characterization and therapeutic potencyMarked calpastatin (CAST) depletion in Alzheimer's disease accelerates cytoskeleton disruption and neurodegeneration: neuroprotection by CAST overexpression.Differential effect of three-repeat and four-repeat tau on mitochondrial axonal transport.TOC1: a valuable tool in assessing disease progression in the rTg4510 mouse model of tauopathy.
P2860
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P248
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P2860
Caspase cleavage of tau: linking amyloid and neurofibrillary tangles in Alzheimer's disease
description
2003 nî lūn-bûn
@nan
2003 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Caspase cleavage of tau: linki ...... tangles in Alzheimer's disease
@ast
Caspase cleavage of tau: linki ...... tangles in Alzheimer's disease
@en
Caspase cleavage of tau: linki ...... tangles in Alzheimer's disease
@en-gb
Caspase cleavage of tau: linki ...... tangles in Alzheimer's disease
@nl
type
label
Caspase cleavage of tau: linki ...... tangles in Alzheimer's disease
@ast
Caspase cleavage of tau: linki ...... tangles in Alzheimer's disease
@en
Caspase cleavage of tau: linki ...... tangles in Alzheimer's disease
@en-gb
Caspase cleavage of tau: linki ...... tangles in Alzheimer's disease
@nl
prefLabel
Caspase cleavage of tau: linki ...... tangles in Alzheimer's disease
@ast
Caspase cleavage of tau: linki ...... tangles in Alzheimer's disease
@en
Caspase cleavage of tau: linki ...... tangles in Alzheimer's disease
@en-gb
Caspase cleavage of tau: linki ...... tangles in Alzheimer's disease
@nl
P2093
P2860
P921
P3181
P356
P1476
Caspase cleavage of tau: linki ...... tangles in Alzheimer's disease
@en
P2093
Aida Abraha
Angara Zambrano
Angela L Guillozet
Francisco Garcia-Sierra
Lester I Binder
Meiling Lu
Nichole LaPointe
Richard Miller
Robert W Berry
P2860
P304
P3181
P356
10.1073/PNAS.1630428100
P407
P577
2003-08-19T00:00:00Z