LAT: the ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation
about
T cell receptor-independent basal signaling via Erk and Abl kinases suppresses RAG gene expressionSystematic identification of regulatory proteins critical for T-cell activationSHP2-interacting transmembrane adaptor protein (SIT), a novel disulfide-linked dimer regulating human T cell activationCAST, a novel CD3epsilon-binding protein transducing activation signal for interleukin-2 production in T cellsFYN-T-FYB-SLP-76 interactions define a T-cell receptor zeta/CD3-mediated tyrosine phosphorylation pathway that up-regulates interleukin 2 transcription in T-cellsFunctional association between SLAP-130 and SLP-76 in Jurkat T cellsA BASH/SLP-76-related adaptor protein MIST/Clnk involved in IgE receptor-mediated mast cell degranulationFyn-binding protein (Fyb)/SLP-76-associated protein (SLAP), Ena/vasodilator-stimulated phosphoprotein (VASP) proteins and the Arp2/3 complex link T cell receptor (TCR) signaling to the actin cytoskeletonPhosphoprotein associated with glycosphingolipid-enriched microdomains (PAG), a novel ubiquitously expressed transmembrane adaptor protein, binds the protein tyrosine kinase csk and is involved in regulation of T cell activationAssociation of Grb2, Gads, and phospholipase C-gamma 1 with phosphorylated LAT tyrosine residues. Effect of LAT tyrosine mutations on T cell angigen receptor-mediated signalingDynamic recruitment of human CD2 into lipid rafts. Linkage to T cell signal transductionStructural and functional dissection of the cytoplasmic domain of the transmembrane adaptor protein SIT (SHP2-interacting transmembrane adaptor protein)Functional cloning of Src-like adapter protein-2 (SLAP-2), a novel inhibitor of antigen receptor signalingA novel Src homology 2 domain-containing molecule, Src-like adapter protein-2 (SLAP-2), which negatively regulates T cell receptor signalingSynergistic assembly of linker for activation of T cells signaling protein complexes in T cell plasma membrane domainsIdentification of substrates of human protein-tyrosine phosphatase PTPN22Recruitment and activation of PLCgamma1 in T cells: a new insight into old domainsThe importance of three membrane-distal tyrosines in the adaptor protein NTAL/LABThe tyrosine phosphatase 1B regulates linker for activation of T-cell phosphorylation and platelet aggregation upon FcgammaRIIa cross-linkingMolecular cloning of a novel gene encoding a membrane-associated adaptor protein (LAX) in lymphocyte signalingThe tyrosine phosphatase CD148 is excluded from the immunologic synapse and down-regulates prolonged T cell signalingT cell receptor (TCR) interacting molecule (TRIM), a novel disulfide-linked dimer associated with the TCR-CD3-zeta complex, recruits intracellular signaling proteins to the plasma membraneHistidine domain-protein tyrosine phosphatase interacts with Grb2 and GrpLCooperative interactions at the SLP-76 complex are critical for actin polymerizationSLP-65 signal transduction requires Src homology 2 domain-mediated membrane anchoring and a kinase-independent adaptor function of SykNon-T cell activation linker (NTAL): a transmembrane adaptor protein involved in immunoreceptor signalingLAB: a new membrane-associated adaptor molecule in B cell activationInterchangeability of Themis1 and Themis2 in thymocyte development reveals two related proteins with conserved molecular functionMapping the Zap-70 phosphorylation sites on LAT (linker for activation of T cells) required for recruitment and activation of signalling proteins in T cellsMona, a novel hematopoietic-specific adaptor interacting with the macrophage colony-stimulating factor receptor, is implicated in monocyte/macrophage development.Regulation of the tyrosine kinase Itk by the peptidyl-prolyl isomerase cyclophilin APositive and negative regulation of T-cell activation through kinases and phosphatasesA PAK1-PIX-PKL complex is activated by the T-cell receptor independent of Nck, Slp-76 and LAT.Functional cooperation between c-Cbl and Src-like adaptor protein 2 in the negative regulation of T-cell receptor signaling.Identification of a phospholipase C-gamma1 (PLC-gamma1) SH3 domain-binding site in SLP-76 required for T-cell receptor-mediated activation of PLC-gamma1 and NFATRegulatory and signaling properties of the Vav familyRIAM regulates the cytoskeletal distribution and activation of PLC-gamma1 in T cellsScaffold proteins: hubs for controlling the flow of cellular informationSLAP, a dimeric adapter protein, plays a functional role in T cell receptor signalingT cell activation
P2860
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P2860
LAT: the ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation
description
1998 nî lūn-bûn
@nan
1998 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
LAT: the ZAP-70 tyrosine kinas ...... eceptor to cellular activation
@ast
LAT: the ZAP-70 tyrosine kinas ...... eceptor to cellular activation
@en
LAT: the ZAP-70 tyrosine kinas ...... eceptor to cellular activation
@en-gb
LAT: the ZAP-70 tyrosine kinas ...... eceptor to cellular activation
@nl
type
label
LAT: the ZAP-70 tyrosine kinas ...... eceptor to cellular activation
@ast
LAT: the ZAP-70 tyrosine kinas ...... eceptor to cellular activation
@en
LAT: the ZAP-70 tyrosine kinas ...... eceptor to cellular activation
@en-gb
LAT: the ZAP-70 tyrosine kinas ...... eceptor to cellular activation
@nl
prefLabel
LAT: the ZAP-70 tyrosine kinas ...... eceptor to cellular activation
@ast
LAT: the ZAP-70 tyrosine kinas ...... eceptor to cellular activation
@en
LAT: the ZAP-70 tyrosine kinas ...... eceptor to cellular activation
@en-gb
LAT: the ZAP-70 tyrosine kinas ...... eceptor to cellular activation
@nl
P2093
P3181
P1433
P1476
LAT: the ZAP-70 tyrosine kinas ...... eceptor to cellular activation
@en
P2093
J Sloan-Lancaster
L E Samelson
R P Trible
P3181
P356
10.1016/S0092-8674(00)80901-0
P407
P577
1998-01-09T00:00:00Z