Phosphoinositide signalling links O-GlcNAc transferase to insulin resistance
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Molecular basis of signaling specificity of insulin and IGF receptors: neglected corners and recent advancesPhosphofructokinase 1 glycosylation regulates cell growth and metabolismStructure of human O-GlcNAc transferase and its complex with a peptide substrateGlucose activates free fatty acid receptor 1 gene transcription via phosphatidylinositol-3-kinase-dependent O-GlcNAcylation of pancreas-duodenum homeobox-1Regulation of insulin receptor substrate 1 (IRS-1)/AKT kinase-mediated insulin signaling by O-Linked beta-N-acetylglucosamine in 3T3-L1 adipocytesO-GlcNAcylation: a bridge between glucose and cell differentiationO-GlcNAcylation and the Metabolic Shift in High-Proliferating Cells: All the Evidence Suggests that Sugars Dictate the Flux of Lipid Biogenesis in Tumor ProcessesPPARs: Protectors or Opponents of Myocardial Function?Functional O-GlcNAc modifications: implications in molecular regulation and pathophysiologyO-GlcNAcylation and Metabolic Reprograming in CancerPosttranslational regulation of Akt in human cancerA Drosophila model of high sugar diet-induced cardiomyopathyStructure of an O-GlcNAc transferase homolog provides insight into intracellular glycosylationChemical Dissection of the Link between Streptozotocin, O-GlcNAc, and Pancreatic Cell DeathStructural insights into mechanism and specificity of O-GlcNAc transferaseElevation of Global O-GlcNAc Levels in 3T3-L1 Adipocytes by Selective Inhibition of O-GlcNAcase Does Not Induce Insulin ResistanceInhibition of O-GlcNAcase Using a Potent and Cell-Permeable Inhibitor Does Not Induce Insulin Resistance in 3T3-L1 AdipocytesA neutral diphosphate mimic crosslinks the active site of human O-GlcNAc transferaseDeep congenic analysis identifies many strong, context-dependent QTLs, one of which, Slc35b4, regulates obesity and glucose homeostasisO-GlcNAc signaling entrains the circadian clock by inhibiting BMAL1/CLOCK ubiquitinationGlucose Alters Per2 Rhythmicity Independent of AMPK, Whereas AMPK Inhibitor Compound C Causes Profound Repression of Clock Genes and AgRP in mHypoE-37 Hypothalamic NeuronsO-GlcNAcylation of cofilin promotes breast cancer cell invasionDifferential effects of an O-GlcNAcase inhibitor on tau phosphorylationO-linked GlcNAcylation elevated by HPV E6 mediates viral oncogenesisThe trafficking/interaction of eNOS and caveolin-1 induced by insulin modulates endothelial nitric oxide productionA PGC-1alpha-O-GlcNAc transferase complex regulates FoxO transcription factor activity in response to glucose.O-GlcNAc regulates FoxO activation in response to glucose.Regulation of calcium/calmodulin-dependent kinase IV by O-GlcNAc modification.Targeted in vivo O-GlcNAc sensors reveal discrete compartment-specific dynamics during signal transduction.Interaction between O-GlcNAc modification and tyrosine phosphorylation of prohibitin: implication for a novel binary switch.O-GlcNAc modifications regulate cell survival and epiboly during zebrafish development.Urea-induced ROS generation causes insulin resistance in mice with chronic renal failure.The hexosamine signaling pathway: O-GlcNAc cycling in feast or famineO-linked beta-N-acetylglucosamine (O-GlcNAc): Extensive crosstalk with phosphorylation to regulate signaling and transcription in response to nutrients and stressO-GlcNAc protein modification in plants: Evolution and function.O-linked N-acetylglucosamine modification of insulin receptor substrate-1 occurs in close proximity to multiple SH2 domain binding motifs.Altering O-linked β-N-acetylglucosamine cycling disrupts mitochondrial function.N-glycan remodeling on glucagon receptor is an effector of nutrient sensing by the hexosamine biosynthesis pathwayInsulin resistance in adolescents with type 1 diabetes and its relationship to cardiovascular function.Quantitative secretome and glycome of primary human adipocytes during insulin resistance.
P2860
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P2860
Phosphoinositide signalling links O-GlcNAc transferase to insulin resistance
description
2008 nî lūn-bûn
@nan
2008 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Phosphoinositide signalling links O-GlcNAc transferase to insulin resistance
@ast
Phosphoinositide signalling links O-GlcNAc transferase to insulin resistance
@en
Phosphoinositide signalling links O-GlcNAc transferase to insulin resistance
@en-gb
Phosphoinositide signalling links O-GlcNAc transferase to insulin resistance
@nl
type
label
Phosphoinositide signalling links O-GlcNAc transferase to insulin resistance
@ast
Phosphoinositide signalling links O-GlcNAc transferase to insulin resistance
@en
Phosphoinositide signalling links O-GlcNAc transferase to insulin resistance
@en-gb
Phosphoinositide signalling links O-GlcNAc transferase to insulin resistance
@nl
prefLabel
Phosphoinositide signalling links O-GlcNAc transferase to insulin resistance
@ast
Phosphoinositide signalling links O-GlcNAc transferase to insulin resistance
@en
Phosphoinositide signalling links O-GlcNAc transferase to insulin resistance
@en-gb
Phosphoinositide signalling links O-GlcNAc transferase to insulin resistance
@nl
P2093
P50
P921
P3181
P356
P1433
P1476
Phosphoinositide signalling links O-GlcNAc transferase to insulin resistance
@en
P2093
Fengxue Zhang
Jeffrey E Kudlow
Joyce C Havstad
Pat P Ongusaha
Philip D Miles
W Venus So
Xiaoyong Yang
P2888
P3181
P356
10.1038/NATURE06668
P407
P577
2008-02-21T00:00:00Z
P5875
P6179
1017436797