The human U5 snRNP-specific 100-kD protein is an RS domain-containing, putative RNA helicase with significant homology to the yeast splicing factor Prp28p.
about
The SR protein familyAlterations in the expression of DEAD-box and other RNA binding proteins during HIV-1 replicationThe human U5-220kD protein (hPrp8) forms a stable RNA-free complex with several U5-specific proteins, including an RNA unwindase, a homologue of ribosomal elongation factor EF-2, and a novel WD-40 proteinHuman homologs of yeast prp16 and prp17 reveal conservation of the mechanism for catalytic step II of pre-mRNA splicingThe human U5-200kD DEXH-box protein unwinds U4/U6 RNA duplices in vitroThe 65 and 110 kDa SR-related proteins of the U4/U6.U5 tri-snRNP are essential for the assembly of mature spliceosomesA novel U2 and U11/U12 snRNP protein that associates with the pre-mRNA branch site.Functional analysis of the promoter of the mitochondrial phosphate carrier human gene: identification of activator and repressor elements and their transcription factorsPrp8 protein: at the heart of the spliceosomep68 RNA helicase is an essential human splicing factor that acts at the U1 snRNA-5' splice site duplex.PRP16, a DEAH-box RNA helicase, is recruited to the spliceosome primarily via its nonconserved N-terminal domainThe C-terminal region of hPrp8 interacts with the conserved GU dinucleotide at the 5' splice siteThe human Prp8 protein is a component of both U2- and U12-dependent spliceosomesSorting out the complexity of SR protein functionsBiochemical and genetic analyses of the U5, U6, and U4/U6 x U5 small nuclear ribonucleoproteins from Saccharomyces cerevisiaePSF and p54nrb bind a conserved stem in U5 snRNADead-box proteins: a family affair--active and passive players in RNP-remodelingExtended base pair complementarity between U1 snRNA and the 5' splice site does not inhibit splicing in higher eukaryotes, but rather increases 5' splice site recognitionStructural and functional analysis of the human spliceosomal DEAD-box helicase Prp28Splicing proofreading at 5' splice sites by ATPase Prp28p.The 100-kda U5 snRNP protein (hPrp28p) contacts the 5' splice site through its ATPase siteDDX23-Linc00630-HDAC1 axis activates the Notch pathway to promote metastasisDistinct domains of splicing factor Prp8 mediate different aspects of spliceosome activationp54(nrb) associates with the 5' splice site within large transcription/splicing complexes.Pre-mRNA splicing is a determinant of histone H3K36 methylationPhosphorylation by SR kinases regulates the binding of PTB-associated splicing factor (PSF) to the pre-mRNA polypyrimidine tract.Proteomic analysis of in vivo-assembled pre-mRNA splicing complexes expands the catalog of participating factors.Functional roles of protein splicing factors.The EF-G-like GTPase Snu114p regulates spliceosome dynamics mediated by Brr2p, a DExD/H box ATPaseSad1 counteracts Brr2-mediated dissociation of U4/U6.U5 in tri-snRNP homeostasis.The pre-mRNA 5' cap determines whether U6 small nuclear RNA succeeds U1 small nuclear ribonucleoprotein particle at 5' splice sites.A spliceosome intermediate with loosely associated tri-snRNP accumulates in the absence of Prp28 ATPase activityHuman U4/U6.U5 and U4atac/U6atac.U5 tri-snRNPs exhibit similar protein compositions.Human Epistatic Interaction Controls IL7R Splicing and Increases Multiple Sclerosis Risk.Modulation of gene expression in MHCC97 cells by interferon alpha.The mammalian homologue of Prp16p is overexpressed in a cell line tolerant to Leflunomide, a new immunoregulatory drug effective against rheumatoid arthritis.An unanticipated early function of DEAD-box ATPase Prp28 during commitment to splicing is modulated by U5 snRNP protein Prp8.Splicosomal and serine and arginine-rich splicing factors as targets for TGF-β.Structural analysis of the spliceosomal RNA helicase Prp28 from the thermophilic eukaryote Chaetomium thermophilum.Dysregulation of spliceosome gene expression in advanced prostate cancer by RNA-binding protein PSF.
P2860
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P2860
The human U5 snRNP-specific 100-kD protein is an RS domain-containing, putative RNA helicase with significant homology to the yeast splicing factor Prp28p.
description
1997 nî lūn-bûn
@nan
1997 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
The human U5 snRNP-specific 10 ...... e yeast splicing factor Prp28p
@nl
The human U5 snRNP-specific 10 ...... yeast splicing factor Prp28p.
@ast
The human U5 snRNP-specific 10 ...... yeast splicing factor Prp28p.
@en
The human U5 snRNP-specific 10 ...... yeast splicing factor Prp28p.
@en-gb
type
label
The human U5 snRNP-specific 10 ...... e yeast splicing factor Prp28p
@nl
The human U5 snRNP-specific 10 ...... yeast splicing factor Prp28p.
@ast
The human U5 snRNP-specific 10 ...... yeast splicing factor Prp28p.
@en
The human U5 snRNP-specific 10 ...... yeast splicing factor Prp28p.
@en-gb
prefLabel
The human U5 snRNP-specific 10 ...... e yeast splicing factor Prp28p
@nl
The human U5 snRNP-specific 10 ...... yeast splicing factor Prp28p.
@ast
The human U5 snRNP-specific 10 ...... yeast splicing factor Prp28p.
@en
The human U5 snRNP-specific 10 ...... yeast splicing factor Prp28p.
@en-gb
P2093
P3181
P1433
P1476
The human U5 snRNP-specific 10 ...... yeast splicing factor Prp28p.
@en
P2093
P304
P3181
P407
P577
1997-11-01T00:00:00Z