about
RanBPM is an inhibitor of ERK signalingDistinct requirement for an intact dimer interface in wild-type, V600E and kinase-dead B-Raf signallingThe MST/Hippo Pathway and Cell Death: A Non-Canonical AffairBRAF Mutation in Colorectal Cancer: An UpdateProhibitins role in cellular survival through Ras-Raf-MEK-ERK pathwayDA-Raf-Mediated Suppression of the Ras--ERK Pathway Is Essential for TGF-β1-Induced Epithelial-Mesenchymal Transition in Alveolar Epithelial Type 2 CellsFunctional Integration of the Conserved Domains of Shoc2 ScaffoldGenetic signature of histiocytic sarcoma revealed by a sleeping beauty transposon genetic screen in miceNovel Carboxamide-Based Allosteric MEK Inhibitors: Discovery and Optimization Efforts toward XL518 (GDC-0973)Raf-interactome in tuning the complexity and diversity of Raf function.Oxidative stress, a trigger of hepatitis C and B virus-induced liver carcinogenesisPhosphodiesterase-8A binds to and regulates Raf-1 kinaseThe RAS-Binding Domain of Human BRAF Protein Serine/Threonine Kinase Exhibits Allosteric Conformational Changes upon Binding HRASActivity of distinct growth factor receptor network components in breast tumors uncovers two biologically relevant subtypesB-Raf regulation of integrin α4β1-mediated resistance to shear stress through changes in cell spreading and cytoskeletal association in T cellsWhen ubiquitination meets phosphorylation: a systems biology perspective of EGFR/MAPK signalling.Resistance to Selumetinib (AZD6244) in colorectal cancer cell lines is mediated by p70S6K and RPS6 activation.Topological and functional properties of the small GTPases protein interaction network.Issues in interpreting the in vivo activity of Aurora-ACompeting to coordinate cell fate decisions: the MST2-Raf-1 signaling devicePseudokinases from a structural perspectiveA Phosphoproteomic Comparison of B-RAFV600E and MKK1/2 Inhibitors in Melanoma Cells.Regulation of ERK-MAPK signaling in human epidermisAn Integrative Approach for Mapping Differentially Expressed Genes and Network Components Using Novel Parameters to Elucidate Key Regulatory Genes in Colorectal Cancer.Activation of RAF1 (c-RAF) by the Marine Alkaloid Lasonolide A Induces Rapid Premature Chromosome Condensation.Drug-induced RAF dimerization is independent of RAS mutation status and does not lead to universal MEK dependence for cell survival in head and neck cancersLapatinib and obatoclax kill tumor cells through blockade of ERBB1/3/4 and through inhibition of BCL-XL and MCL-1.Exome Sequencing in Classic Hairy Cell Leukaemia Reveals Widespread Variation in Acquired Somatic Mutations between Individual Tumours Apart from the Signature BRAF V(600)E Lesion.Kinase-independent role for CRAF-driving tumour radioresistance via CHK2High sensitivity isoelectric focusing to establish a signaling biomarker for the diagnosis of human colorectal cancer.Crosstalk Between MAPK/ERK and PI3K/AKT Signal Pathways During Brain Ischemia/ReperfusionIncreased BRAF heterodimerization is the common pathogenic mechanism for noonan syndrome-associated RAF1 mutantsFrequency modulation of ERK activation dynamics rewires cell fate.Protein kinases of the Hippo pathway: regulation and substrates.SEL-10/Fbw7-dependent negative feedback regulation of LIN-45/Braf signaling in C. elegans via a conserved phosphodegron.Phosphorylation of RAF Kinase Dimers Drives Conformational Changes that Facilitate Transactivation.Quantitative proteomics and phosphoproteomics on serial tumor biopsies from a sorafenib-treated HCC patientMEK-1 activates C-Raf through a Ras-independent mechanism.HDAC inhibitors suppress c-Jun/Fra-1-mediated proliferation through transcriptionally downregulating MKK7 and Raf1 in neuroblastoma cells.A negative-feedback loop regulating ERK1/2 activation and mediated by RasGPR2 phosphorylation.
P2860
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P2860
description
2011 nî lūn-bûn
@nan
2011 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մարտին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Raf family kinases: old dogs have learned new tricks
@ast
Raf family kinases: old dogs have learned new tricks
@en
Raf family kinases: old dogs have learned new tricks
@en-gb
Raf family kinases: old dogs have learned new tricks
@nl
type
label
Raf family kinases: old dogs have learned new tricks
@ast
Raf family kinases: old dogs have learned new tricks
@en
Raf family kinases: old dogs have learned new tricks
@en-gb
Raf family kinases: old dogs have learned new tricks
@nl
prefLabel
Raf family kinases: old dogs have learned new tricks
@ast
Raf family kinases: old dogs have learned new tricks
@en
Raf family kinases: old dogs have learned new tricks
@en-gb
Raf family kinases: old dogs have learned new tricks
@nl
P2860
P50
P3181
P356
P1433
P1476
Raf family kinases: old dogs have learned new tricks
@en
P2093
David Romano
P2860
P304
P3181
P356
10.1177/1947601911407323
P407
P577
2011-03-01T00:00:00Z