Yeast spindle pole body duplication gene MPS1 encodes an essential dual specificity protein kinase
about
A centrosomal function for the human Nek2 protein kinase, a member of the NIMA family of cell cycle regulators.Human Mps1 kinase is required for the spindle assembly checkpoint but not for centrosome duplicationAscospore formation in the yeast Saccharomyces cerevisiae.Human Mps1 protein kinase is required for centrosome duplication and normal mitotic progressionA mammalian homolog of yeast MOB1 is both a member and a putative substrate of striatin family-protein phosphatase 2A complexesAnalysis of phosphorylation sites on proteins from Saccharomyces cerevisiae by electron transfer dissociation (ETD) mass spectrometry.Human MPS1 kinase is required for mitotic arrest induced by the loss of CENP-E from kinetochoresThe Schizosaccharomyces pombe spindle checkpoint protein mad2p blocks anaphase and genetically interacts with the anaphase-promoting complexStructural and mechanistic insights into Mps1 kinase activationSmall-molecule kinase inhibitors provide insight into Mps1 cell cycle functionScaffold-Focused Virtual Screening: Prospective Application to the Discovery of TTK InhibitorsStructure-Based Design of Orally Bioavailable 1 H -Pyrrolo[3,2- c ]pyridine Inhibitors of Mitotic Kinase Monopolar Spindle 1 (MPS1)Saccharomyces cerevisiae MPS2 encodes a membrane protein localized at the spindle pole body and the nuclear envelope.Saccharomyces cerevisiae genes required in the absence of the CIN8-encoded spindle motor act in functionally diverse mitotic pathways.Yeast Mps1p phosphorylates the spindle pole component Spc110p in the N-terminal domainThe Bbp1p-Mps2p complex connects the SPB to the nuclear envelope and is essential for SPB duplication.Associations among PH and SH3 domain-containing proteins and Rho-type GTPases in YeastThe yeast centrin, cdc31p, and the interacting protein kinase, Kic1p, are required for cell integrityThe yeast CDC37 gene interacts with MPS1 and is required for proper execution of spindle pole body duplication.The yeast protein kinase Mps1p is required for assembly of the integral spindle pole body component Spc42p.Mimicking Ndc80 phosphorylation triggers spindle assembly checkpoint signallingThe Saccharomyces cerevisiae spindle pole body duplication gene MPS1 is part of a mitotic checkpoint.Role of calmodulin and Spc110p interaction in the proper assembly of spindle pole body compenents.Structural and functional characterization of the protein kinase Mps1 in Arabidopsis thalianaCharacterization of a putative spindle assembly checkpoint kinase Mps1, suggests its involvement in cell division, morphogenesis and oxidative stress tolerance in Candida albicansDiverse functions of spindle assembly checkpoint genes in Saccharomyces cerevisiae.Recognizing chromosomes in trouble: association of the spindle checkpoint protein Bub3p with altered kinetochores and a unique defective centromere.TagSmart: analysis and visualization for yeast mutant fitness data measured by tag microarrays.Systematic analysis of essential genes reveals important regulators of G protein signaling.The MPS1 family of protein kinases.Bub1p kinase activates the Saccharomyces cerevisiae spindle assembly checkpoint.N-terminal regions of Mps1 kinase determine functional bifurcation.DBF2 protein kinase binds to and acts through the cell cycle-regulated MOB1 protein.Saccharomyces cerevisiae Mob1p is required for cytokinesis and mitotic exit.Cellular abundance of Mps1 and the role of its carboxyl terminal tail in substrate recruitment.Mps1p regulates meiotic spindle pole body duplication in addition to having novel roles during sporulation.Bub1, Sgo1, and Mps1 mediate a distinct pathway for chromosome biorientation in budding yeast.Mip1 associates with both the Mps1 kinase and actin, and is required for cell cortex stability and anaphase spindle positioning.Centromere-tethered Mps1 pombe homolog (Mph1) kinase is a sufficient marker for recruitment of the spindle checkpoint protein Bub1, but not Mad1.Pds1p is required for faithful execution of anaphase in the yeast, Saccharomyces cerevisiae
P2860
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P2860
Yeast spindle pole body duplication gene MPS1 encodes an essential dual specificity protein kinase
description
1995 nî lūn-bûn
@nan
1995 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
Yeast spindle pole body duplic ...... ual specificity protein kinase
@ast
Yeast spindle pole body duplic ...... ual specificity protein kinase
@en
Yeast spindle pole body duplic ...... ual specificity protein kinase
@en-gb
Yeast spindle pole body duplic ...... ual specificity protein kinase
@nl
type
label
Yeast spindle pole body duplic ...... ual specificity protein kinase
@ast
Yeast spindle pole body duplic ...... ual specificity protein kinase
@en
Yeast spindle pole body duplic ...... ual specificity protein kinase
@en-gb
Yeast spindle pole body duplic ...... ual specificity protein kinase
@nl
prefLabel
Yeast spindle pole body duplic ...... ual specificity protein kinase
@ast
Yeast spindle pole body duplic ...... ual specificity protein kinase
@en
Yeast spindle pole body duplic ...... ual specificity protein kinase
@en-gb
Yeast spindle pole body duplic ...... ual specificity protein kinase
@nl
P2093
P2860
P3181
P1433
P1476
Yeast spindle pole body duplic ...... ual specificity protein kinase
@en
P2093
P2860
P304
P3181
P407
P577
1995-04-18T00:00:00Z