Mechanism of microhomology-mediated end-joining promoted by human DNA polymerase θ
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Homologous Recombination Deficiency: Exploiting the Fundamental Vulnerability of Ovarian CancerDNA Damage and Pulmonary HypertensionDNA polymerase θ (POLQ), double-strand break repair, and cancerDNA Polymerase θ: A Unique Multifunctional End-Joining MachineReplication fork instability and the consequences of fork collisions from rereplicationNoncanonical views of homology-directed DNA repairMicrohomology-Mediated End Joining: A Back-up Survival Mechanism or Dedicated Pathway?miR-155 Overexpression Promotes Genomic Instability by Reducing High-fidelity Polymerase Delta Expression and Activating Error-Prone DSB RepairMicrohomology-mediated end joining: new players join the teamDrosophila DNA polymerase theta utilizes both helicase-like and polymerase domains during microhomology-mediated end joining and interstrand crosslink repairError-Prone Repair of DNA Double-Strand Breaks.Primase-polymerases are a functionally diverse superfamily of replication and repair enzymes.Human DNA polymerase θ grasps the primer terminus to mediate DNA repairAlu-mediated diverse and complex pathogenic copy-number variants within human chromosome 17 at p13.3.Roles of Residues Arg-61 and Gln-38 of Human DNA Polymerase η in Bypass of Deoxyguanosine and 7,8-Dihydro-8-oxo-2'-deoxyguanosine.Polymerase Θ is a key driver of genome evolution and of CRISPR/Cas9-mediated mutagenesisDeciphering the BRCA1 Tumor Suppressor Network.EEPD1 Rescues Stressed Replication Forks and Maintains Genome Stability by Promoting End Resection and Homologous Recombination Repair.A role for human homologous recombination factors in suppressing microhomology-mediated end joiningGenomic Scars Generated by Polymerase Theta Reveal the Versatile Mechanism of Alternative End-Joining.Mechanisms for Complex Chromosomal Insertions.Substitutions of short heterologous DNA segments of intragenomic or extragenomic origins produce clustered genomic polymorphisms.NBS1 Phosphorylation Status Dictates Repair Choice of Dysfunctional Telomeres.Zinc finger nuclease-based double-strand breaks attenuate malaria parasites and reveal rare microhomology-mediated end joining.Linking DNA polymerase theta structure and function in health and diseaseComplex interactions between the DNA-damage response and mammalian telomeres.High Quality Maize Centromere 10 Sequence Reveals Evidence of Frequent Recombination Events.Repair Pathway Choices and Consequences at the Double-Strand BreakRisky business: Microhomology-mediated end joining.Polymerase θ is a robust terminal transferase that oscillates between three different mechanisms during end-joiningFANCD2 Maintains Fork Stability in BRCA1/2-Deficient Tumors and Promotes Alternative End-Joining DNA Repair.Homology directed repair is unaffected by the absence of siRNAs in Drosophila melanogaster.The DNA resection protein CtIP promotes mammary tumorigenesis.Excess Polθ functions in response to replicative stress in homologous recombination-proficient cancer cells.DNA polymerase θ specializes in incorporating synthetic expanded-size (xDNA) nucleotidesRad52 competes with Ku70/Ku86 for binding to S-region DSB ends to modulate antibody class-switch DNA recombination.Stop pulling my strings - what telomeres taught us about the DNA damage response.CRISPR/Cas9-mediated genome engineering of CHO cell factories: Application and perspectives.Deciphering the Code of the Cancer Genome: Mechanisms of Chromosome Rearrangement.A Scalable Epitope Tagging Approach for High Throughput ChIP-Seq Analysis.
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P2860
Mechanism of microhomology-mediated end-joining promoted by human DNA polymerase θ
description
2015 nî lūn-bûn
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2015 թուականի Մարտին հրատարակուած գիտական յօդուած
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2015 թվականի մարտին հրատարակված գիտական հոդված
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2015年の論文
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2015年論文
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2015年論文
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2015年論文
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2015年論文
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2015年論文
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2015年论文
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name
Mechanism of microhomology-mediated end-joining promoted by human DNA polymerase θ
@ast
Mechanism of microhomology-mediated end-joining promoted by human DNA polymerase θ
@en
Mechanism of microhomology-mediated end-joining promoted by human DNA polymerase θ
@en-gb
Mechanism of microhomology-mediated end-joining promoted by human DNA polymerase θ
@nl
type
label
Mechanism of microhomology-mediated end-joining promoted by human DNA polymerase θ
@ast
Mechanism of microhomology-mediated end-joining promoted by human DNA polymerase θ
@en
Mechanism of microhomology-mediated end-joining promoted by human DNA polymerase θ
@en-gb
Mechanism of microhomology-mediated end-joining promoted by human DNA polymerase θ
@nl
prefLabel
Mechanism of microhomology-mediated end-joining promoted by human DNA polymerase θ
@ast
Mechanism of microhomology-mediated end-joining promoted by human DNA polymerase θ
@en
Mechanism of microhomology-mediated end-joining promoted by human DNA polymerase θ
@en-gb
Mechanism of microhomology-mediated end-joining promoted by human DNA polymerase θ
@nl
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P1476
Mechanism of microhomology-mediated end-joining promoted by human DNA polymerase θ
@en
P2093
Ahmet Y Ozdemir
Gurushankar Chandramouly
Richard T Pomerantz
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P2888
P304
P3181
P356
10.1038/NSMB.2961
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P577
2015-02-02T00:00:00Z
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1013858846