SUR-8, a conserved Ras-binding protein with leucine-rich repeats, positively regulates Ras-mediated signaling in C. elegans
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Genetic and functional characterization of putative Ras/Raf interaction inhibitors in C. elegans and mammalian cellsMutation of SHOC2 promotes aberrant protein N-myristoylation and causes Noonan-like syndrome with loose anagen hairThe leucine-rich repeat protein SUR-8 enhances MAP kinase activation and forms a complex with Ras and RafDensin-180: revised membrane topology, domain structure and phosphorylation statusScaffold Proteins Regulating Extracellular Regulated Kinase Function in Cardiac Hypertrophy and DiseaseShoc2 is targeted to late endosomes and required for Erk1/2 activation in EGF-stimulated cellsFunctional Integration of the Conserved Domains of Shoc2 ScaffoldAnalysis of the role of the hypervariable region of yeast Ras2p and its farnesylation in the interaction with exchange factors and adenylyl cyclase.SCOP, a novel gene product expressed in a circadian manner in rat suprachiasmatic nucleusEpidermal growth factor treatment enhances the kinase activity of kinase suppressor of RasErbin suppresses the MAP kinase pathwayFibroblast growth factor signaling in Caenorhabditis elegansThe Erbin PDZ domain binds with high affinity and specificity to the carboxyl termini of delta-catenin and ARVCFA functional screen reveals an extensive layer of transcriptional and splicing control underlying RAS/MAPK signaling in DrosophilaSuprachiasmatic nucleus circadian oscillatory protein, a novel binding partner of K-Ras in the membrane rafts, negatively regulates MAPK pathwayThe Caenorhabditis elegans EGL-15 signaling pathway implicates a DOS-like multisubstrate adaptor protein in fibroblast growth factor signal transduction.Ras effector switching promotes divergent cell fates in C. elegans vulval patterning.Bioluminescence resonance energy transfer identify scaffold protein CNK1 interactions in intact cells.How Genetics Has Helped Piece Together the MAPK Signaling Pathway.Ras and calcium signaling pathways converge at Raf1 via the Shoc2 scaffold proteinNoonan syndrome: clinical aspects and molecular pathogenesis.Cancer models in Caenorhabditis elegans.Caenorhabditis elegans CNK-1 promotes Raf activation but is not essential for Ras/Raf signalingThe retinoblastoma protein is linked to the activation of Ras.A gain-of-function allele of cbp-1, the Caenorhabditis elegans ortholog of the mammalian CBP/p300 gene, causes an increase in histone acetyltransferase activity and antagonism of activated Ras.Modulation of KSR activity in Caenorhabditis elegans by Zn ions, PAR-1 kinase and PP2A phosphataseBasolateral targeting by leucine-rich repeat domains in epithelial cells.RAB-7 antagonizes LET-23 EGFR signaling during vulva development in Caenorhabditis elegansHUWE1 is a molecular link controlling RAF-1 activity supported by the Shoc2 scaffold.Disorders of dysregulated signal traffic through the RAS-MAPK pathway: phenotypic spectrum and molecular mechanismsRas isoform-specific signaling: location, location, location.The CRAL/TRIO and GOLD domain protein CGR-1 promotes induction of vulval cell fates in Caenorhabditis elegans and interacts genetically with the Ras signaling pathway.Caenorhabditis elegans lin-25: a study of its role in multiple cell fate specification events involving Ras and the identification and characterization of evolutionarily conserved domains.Noonan syndrome and clinically related disorders.Shoc2/Sur8 protein regulates neurite outgrowthImpact of natural genetic variation on gene expression dynamics.A PP2A regulatory subunit positively regulates Ras-mediated signaling during Caenorhabditis elegans vulval inductionThe Rheb switch 2 segment is critical for signaling to target of rapamycin complex 1.C. elegans EOR-1/PLZF and EOR-2 positively regulate Ras and Wnt signaling and function redundantly with LIN-25 and the SUR-2 Mediator componentActivated EGL-15 FGF receptor promotes protein degradation in muscles of Caenorhabditis elegans
P2860
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P2860
SUR-8, a conserved Ras-binding protein with leucine-rich repeats, positively regulates Ras-mediated signaling in C. elegans
description
1998 nî lūn-bûn
@nan
1998 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
SUR-8, a conserved Ras-binding ...... diated signaling in C. elegans
@ast
SUR-8, a conserved Ras-binding ...... diated signaling in C. elegans
@en
SUR-8, a conserved Ras-binding ...... diated signaling in C. elegans
@en-gb
SUR-8, a conserved Ras-binding ...... diated signaling in C. elegans
@nl
type
label
SUR-8, a conserved Ras-binding ...... diated signaling in C. elegans
@ast
SUR-8, a conserved Ras-binding ...... diated signaling in C. elegans
@en
SUR-8, a conserved Ras-binding ...... diated signaling in C. elegans
@en-gb
SUR-8, a conserved Ras-binding ...... diated signaling in C. elegans
@nl
prefLabel
SUR-8, a conserved Ras-binding ...... diated signaling in C. elegans
@ast
SUR-8, a conserved Ras-binding ...... diated signaling in C. elegans
@en
SUR-8, a conserved Ras-binding ...... diated signaling in C. elegans
@en-gb
SUR-8, a conserved Ras-binding ...... diated signaling in C. elegans
@nl
P2093
P921
P3181
P1433
P1476
SUR-8, a conserved Ras-binding ...... diated signaling in C. elegans
@en
P2093
P304
P3181
P356
10.1016/S0092-8674(00)81227-1
P407
P577
1998-07-10T00:00:00Z