Phosphorylation of human Sgo1 by NEK2A is essential for chromosome congression in mitosis
about
Phosphorylation of HsMis13 by Aurora B kinase is essential for assembly of functional kinetochoreNek2 activation of Kif24 ensures cilium disassembly during the cell cycleBod1 regulates protein phosphatase 2A at mitotic kinetochoresThe 68-kDa telomeric repeat binding factor 1 (TRF1)-associated protein (TAP68) interacts with and recruits TRF1 to the spindle pole during mitosisThe spatiotemporal dynamics of chromatin protein HP1α is essential for accurate chromosome segregation during cell division.Differential expression of centrosome regulators in Her2+ breast cancer cells versus non-tumorigenic MCF10A cells.Role of NEK2A in human cancer and its therapeutic potentials.Aurora B kinase activation requires survivin priming phosphorylation by PLK1.Giardia lamblia Nek1 and Nek2 kinases affect mitosis and excystation.SUV39H1 orchestrates temporal dynamics of centromeric methylation essential for faithful chromosome segregation in mitosis.Centromere cohesion: regulating the guardian.Targeting NEK2 as a promising therapeutic approach for cancer treatment.Shugoshins function as a guardian for chromosomal stability in nuclear division.NEK2 induces drug resistance mainly through activation of efflux drug pumps and is associated with poor prognosis in myeloma and other cancers.Preclinical activity of MBM-5 in gastrointestinal cancer by inhibiting NEK2 kinase activity.Nek2 and Plk4: prognostic markers, drivers of breast tumorigenesis and drug resistance.Mitotic checkpoint control and chromatin remodeling.Ubiquitin, the centrosome, and chromosome segregation.Cancerous inhibitor of protein phosphatase 2A promotes premature chromosome segregation and aneuploidy in prostate cancer cells through association with shugoshin.The histone acetyltransferase component TRRAP is targeted for destruction during the cell cycle.Nek2A contributes to tumorigenic growth and possibly functions as potential therapeutic target for human breast cancer.Irreversible Nek2 kinase inhibitors with cellular activity.The E2F activators control multiple mitotic regulators and maintain genomic integrity through Sgo1 and BubR1.Destabilizing NEK2 overcomes resistance to proteasome inhibition in multiple myeloma.
P2860
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P2860
Phosphorylation of human Sgo1 by NEK2A is essential for chromosome congression in mitosis
description
2007 nî lūn-bûn
@nan
2007 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Phosphorylation of human Sgo1 by NEK2A is essential for chromosome congression in mitosis
@ast
Phosphorylation of human Sgo1 by NEK2A is essential for chromosome congression in mitosis
@en
Phosphorylation of human Sgo1 by NEK2A is essential for chromosome congression in mitosis
@en-gb
Phosphorylation of human Sgo1 by NEK2A is essential for chromosome congression in mitosis
@nl
type
label
Phosphorylation of human Sgo1 by NEK2A is essential for chromosome congression in mitosis
@ast
Phosphorylation of human Sgo1 by NEK2A is essential for chromosome congression in mitosis
@en
Phosphorylation of human Sgo1 by NEK2A is essential for chromosome congression in mitosis
@en-gb
Phosphorylation of human Sgo1 by NEK2A is essential for chromosome congression in mitosis
@nl
prefLabel
Phosphorylation of human Sgo1 by NEK2A is essential for chromosome congression in mitosis
@ast
Phosphorylation of human Sgo1 by NEK2A is essential for chromosome congression in mitosis
@en
Phosphorylation of human Sgo1 by NEK2A is essential for chromosome congression in mitosis
@en-gb
Phosphorylation of human Sgo1 by NEK2A is essential for chromosome congression in mitosis
@nl
P2093
P921
P356
P1433
P1476
Phosphorylation of human Sgo1 by NEK2A is essential for chromosome congression in mitosis
@en
P2093
Felix Aikhionbare
Guosheng Fu
Jianhui Yao
Xuebiao Yao
P2888
P304
P356
10.1038/CR.2007.55
P407
P50
P577
2007-07-01T00:00:00Z
P5875
P6179
1013707553