The molecular basis of Rieger syndrome. Analysis of Pitx2 homeodomain protein activities
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Functional analysis of human mutations in homeodomain transcription factor PITX3Transcriptional antagonism between Hmx1 and Nkx2.5 for a shared DNA-binding siteIdentification of a dominant negative homeodomain mutation in Rieger syndromeDominant negative dimerization of a mutant homeodomain protein in Axenfeld-Rieger syndromeInteraction, cooperative promoter modulation, and renal colocalization of GCMa and Pitx2Cell-specific activation of the atrial natriuretic factor promoter by PITX2 and MEF2AA model for the molecular underpinnings of tooth defects in Axenfeld-Rieger syndromeHistone H2A monoubiquitination represses transcription by inhibiting RNA polymerase II transcriptional elongationPITX2 regulates procollagen lysyl hydroxylase (PLOD) gene expression: implications for the pathology of Rieger syndromeRegulated subset of G1 growth-control genes in response to derepression by the Wnt pathwayAntagonistic regulation of Dlx2 expression by PITX2 and Msx2: implications for tooth developmentDifferential regulation of gene expression by PITX2 isoformsPitx3 activates mouse tyrosine hydroxylase promoter via a high-affinity binding sitePitx2-mediated cardiac outflow tract remodeling.Pitx2, an atrial fibrillation predisposition gene, directly regulates ion transport and intercalated disc genes.Pitx2 in Embryonic and Adult MyogenesisAn unusual class of PITX2 mutations in Axenfeld-Rieger syndrome.Pitx2-dependent occupancy by histone deacetylases is associated with T-box gene regulation in mammalian abdominal tissue.Multifunctional role of the Pitx2 homeodomain protein C-terminal tail.MIP/Aquaporin 0 represents a direct transcriptional target of PITX3 in the developing lens.Pitx2a expression alters actin-myosin cytoskeleton and migration of HeLa cells through Rho GTPase signalingRedox or death: checking on fetal myogenesis.Prediction of regulatory networks in mouse abdominal wallA pituitary homeobox 2 (Pitx2):microRNA-200a-3p:β-catenin pathway converts mesenchymal cells to amelogenin-expressing dental epithelial cellsMicroRNAs regulate pituitary development, and microRNA 26b specifically targets lymphoid enhancer factor 1 (Lef-1), which modulates pituitary transcription factor 1 (Pit-1) expression.Loss of abdominal muscle in Pitx2 mutants associated with altered axial specification of lateral plate mesoderm.Expression of Pitx2 in stromal cells is required for normal hematopoiesisThe Pitx2c N-terminal domain is a critical interaction domain required for asymmetric morphogenesis.Pleiotropic and isoform-specific functions for Pitx2 in superior colliculus and hypothalamic neuronal developmentDact2 represses PITX2 transcriptional activation and cell proliferation through Wnt/beta-catenin signaling during odontogenesis.Novel expression and transcriptional regulation of FoxJ1 during oro-facial morphogenesisEffect of PITX2 knockdown on transcriptome of primary human trabecular meshwork cell culturesHierarchical interactions of homeodomain and forkhead transcription factors in regulating odontogenic gene expression.PITX2 gain-of-function in Rieger syndrome eye model.Functional interactions between Dlx2 and lymphoid enhancer factor regulate Msx2.Rs7193343 polymorphism in zinc finger homeobox 3 (ZFHX3) gene and atrial fibrillation: an updated meta-analysis of 10 case-control comparisons.A zebrafish model of axenfeld-rieger syndrome reveals that pitx2 regulation by retinoic acid is essential for ocular and craniofacial development.PITX2 and beta-catenin interactions regulate Lef-1 isoform expression.Chromatin-associated HMG-17 is a major regulator of homeodomain transcription factor activity modulated by Wnt/beta-catenin signalingDeletion of G protein-coupled receptor 48 leads to ocular anterior segment dysgenesis (ASD) through down-regulation of Pitx2.
P2860
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P248
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P2860
The molecular basis of Rieger syndrome. Analysis of Pitx2 homeodomain protein activities
description
1998 nî lūn-bûn
@nan
1998 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
The molecular basis of Rieger syndrome. Analysis of Pitx2 homeodomain protein activities
@ast
The molecular basis of Rieger syndrome. Analysis of Pitx2 homeodomain protein activities
@en
The molecular basis of Rieger syndrome. Analysis of Pitx2 homeodomain protein activities
@en-gb
The molecular basis of Rieger syndrome. Analysis of Pitx2 homeodomain protein activities
@nl
type
label
The molecular basis of Rieger syndrome. Analysis of Pitx2 homeodomain protein activities
@ast
The molecular basis of Rieger syndrome. Analysis of Pitx2 homeodomain protein activities
@en
The molecular basis of Rieger syndrome. Analysis of Pitx2 homeodomain protein activities
@en-gb
The molecular basis of Rieger syndrome. Analysis of Pitx2 homeodomain protein activities
@nl
prefLabel
The molecular basis of Rieger syndrome. Analysis of Pitx2 homeodomain protein activities
@ast
The molecular basis of Rieger syndrome. Analysis of Pitx2 homeodomain protein activities
@en
The molecular basis of Rieger syndrome. Analysis of Pitx2 homeodomain protein activities
@en-gb
The molecular basis of Rieger syndrome. Analysis of Pitx2 homeodomain protein activities
@nl
P2093
P2860
P921
P356
P1476
The molecular basis of Rieger syndrome. Analysis of Pitx2 homeodomain protein activities
@en
P2093
B A Amendt
E V Semina
L B Sutherland
P2860
P304
P356
10.1074/JBC.273.32.20066
P407
P577
1998-08-07T00:00:00Z