Identification of protein p270/Tpr as a constitutive component of the nuclear pore complex-attached intranuclear filaments
about
Functional analysis of Tpr: identification of nuclear pore complex association and nuclear localization domains and a role in mRNA exportA conserved biogenesis pathway for nucleoporins: proteolytic processing of a 186-kilodalton precursor generates Nup98 and the novel nucleoporin, Nup96A novel helicase-type protein in the nucleolus: protein NOH61A new spectrin, beta IV, has a major truncated isoform that associates with promyelocytic leukemia protein nuclear bodies and the nuclear matrixAmino acid substitutions of coiled-coil protein Tpr abrogate anchorage to the nuclear pore complex but not parallel, in-register homodimerizationTpr is localized within the nuclear basket of the pore complex and has a role in nuclear protein exportNucleocytoplasmic transport of proteins and poly(A)+ RNA in reconstituted Tpr-less nuclei in living mammalian cellsHSF1-TPR interaction facilitates export of stress-induced HSP70 mRNANucleoporins as components of the nuclear pore complex core structure and Tpr as the architectural element of the nuclear basketNucleoporin translocated promoter region (Tpr) associates with dynein complex, preventing chromosome lagging formation during mitosis.The subcellular distribution and function of MTA1 in cancer differentiationLocalization of nucleoporin Tpr to the nuclear pore complex is essential for Tpr mediated regulation of the export of unspliced RNA.The Tpr protein regulates export of mRNAs with retained introns that traffic through the Nxf1 pathway.Direct interaction with nup153 mediates binding of Tpr to the periphery of the nuclear pore complexEnzymes of the SUMO modification pathway localize to filaments of the nuclear pore complex.Protein Tpr is required for establishing nuclear pore-associated zones of heterochromatin exclusionTpr directly binds to Mad1 and Mad2 and is important for the Mad1-Mad2-mediated mitotic spindle checkpointSpatiotemporal control of mitosis by the conserved spindle matrix protein MegatorNup93, a vertebrate homologue of yeast Nic96p, forms a complex with a novel 205-kDa protein and is required for correct nuclear pore assemblyPolyglutamine expansion of huntingtin impairs its nuclear exportDetergent-salt resistance of LAP2alpha in interphase nuclei and phosphorylation-dependent association with chromosomes early in nuclear assembly implies functions in nuclear structure dynamics.Nup153 is an M9-containing mobile nucleoporin with a novel Ran-binding domainNuclear actin extends, with no contraction in sight.The nucleoporin Nup153 is required for nuclear pore basket formation, nuclear pore complex anchoring and import of a subset of nuclear proteinsHalf a century of "the nuclear matrix"Nup50, a nucleoplasmically oriented nucleoporin with a role in nuclear protein exportDepletion of a single nucleoporin, Nup107, prevents the assembly of a subset of nucleoporins into the nuclear pore complexThe nucleoporin nup153 plays a critical role in multiple types of nuclear exportRanGTP-mediated nuclear export of karyopherin alpha involves its interaction with the nucleoporin Nup153A role for RanBP1 in the release of CRM1 from the nuclear pore complex in a terminal step of nuclear exportMajor binding sites for the nuclear import receptor are the internal nucleoporin Nup153 and the adjacent nuclear filament protein TprComplex Commingling: Nucleoporins and the Spindle Assembly CheckpointSac3 is an mRNA export factor that localizes to cytoplasmic fibrils of nuclear pore complex.The C-terminal domain of myosin-like protein 1 (Mlp1p) is a docking site for heterogeneous nuclear ribonucleoproteins that are required for mRNA export.Perinuclear Mlp proteins downregulate gene expression in response to a defect in mRNA exportProteins connecting the nuclear pore complex with the nuclear interiorThe nuclear basket proteins Mlp1p and Mlp2p are part of a dynamic interactome including Esc1p and the proteasome.Nuclear pore complexes in the organization of silent telomeric chromatin.The nucleoporin Nup98 is a site for GDP/GTP exchange on ran and termination of karyopherin beta 2-mediated nuclear importIdentification of novel ERK2 substrates through use of an engineered kinase and ATP analogs
P2860
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P2860
Identification of protein p270/Tpr as a constitutive component of the nuclear pore complex-attached intranuclear filaments
description
1997 nî lūn-bûn
@nan
1997 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Identification of protein p270 ...... ttached intranuclear filaments
@ast
Identification of protein p270 ...... ttached intranuclear filaments
@en
Identification of protein p270 ...... ttached intranuclear filaments
@en-gb
Identification of protein p270 ...... ttached intranuclear filaments
@nl
type
label
Identification of protein p270 ...... ttached intranuclear filaments
@ast
Identification of protein p270 ...... ttached intranuclear filaments
@en
Identification of protein p270 ...... ttached intranuclear filaments
@en-gb
Identification of protein p270 ...... ttached intranuclear filaments
@nl
prefLabel
Identification of protein p270 ...... ttached intranuclear filaments
@ast
Identification of protein p270 ...... ttached intranuclear filaments
@en
Identification of protein p270 ...... ttached intranuclear filaments
@en-gb
Identification of protein p270 ...... ttached intranuclear filaments
@nl
P2093
P2860
P356
P1476
Identification of protein p270 ...... ttached intranuclear filaments
@en
P2093
H R Rackwitz
S Reidenbach
V C Cordes
W W Franke
P2860
P304
P356
10.1083/JCB.136.3.515
P407
P577
1997-02-10T00:00:00Z