Alternative splicing of Pax-8 gene transcripts is developmentally regulated and generates isoforms with different transactivation properties
about
PAX 8 regulates human WT1 transcription through a novel DNA binding sitePAX8-mediated activation of the wt1 tumor suppressor genePAX8 mutations associated with congenital hypothyroidism caused by thyroid dysgenesisPTIP, a novel BRCT domain-containing protein interacts with Pax2 and is associated with active chromatin.An alternatively spliced isoform of transcriptional repressor ATF3 and its induction by stress stimuliWBP-2, a WW domain binding protein, interacts with the thyroid-specific transcription factor Pax8Dominant negative murine serum response factor: alternative splicing within the activation domain inhibits transactivation of serum response factor binding targetsDeregulated expression of PAX5 in medulloblastomaMolecular cloning and characterization of a human PAX-7 cDNA expressed in normal and neoplastic myocytesDeregulation of PAX-5 by translocation of the Emu enhancer of the IgH locus adjacent to two alternative PAX-5 promoters in a diffuse large-cell lymphomaMutation of the PAX6 gene in patients with autosomal dominant keratitisGene content and function of the ancestral chromosome fusion site in human chromosome 2q13-2q14.1 and paralogous regionsThe Solution Structure of DNA-free Pax-8 Paired Box Domain Accounts for Redox Regulation of Transcriptional Activity in the Pax Protein FamilyThe paired domain-containing factor Pax8 and the homeodomain-containing factor TTF-1 directly interact and synergistically activate transcriptionPAX6 gene dosage effect in a family with congenital cataracts, aniridia, anophthalmia and central nervous system defectsDistinct functional properties of three human paired-box-protein, PAX8, isoforms generated by alternative splicing in thyroid, kidney and Wilms' tumorsBioinformatics prediction of overlapping frameshifted translation products in mammalian transcripts.Increased paired box transcription factor 8 has a survival function in gliomaAn alternatively spliced form of the transcription factor Sp1 containing only a single glutamine-rich transactivation domain.Alternatively spliced insertions in the paired domain restrict the DNA sequence specificity of Pax6 and Pax8.Eyg and Ey Pax proteins act by distinct transcriptional mechanisms in Drosophila development.Transcriptomic analysis brings new insight into the biological role of the prion protein during mouse embryogenesisIdentification of a novel pax8 gene sequence variant in four members of the same family: from congenital hypothyroidism with thyroid hypoplasia to mild subclinical hypothyroidism.Pax3 inhibits myogenic differentiation of cultured myoblast cells.Mutation of the PAX2 gene in a family with optic nerve colobomas, renal anomalies and vesicoureteral reflux.The Pax2 homolog sparkling is required for development of cone and pigment cells in the Drosophila eye.Interaction between Pax6 and its novel mutant in Bufo raddei StrauchPax2/5/8 and Pax6 alternative splicing events in basal chordates and vertebrates: a focus on paired box domain.Regulation of gene expression by Pax6 in ocular cells: a case of tissue-preferred expression of crystallins in lens.Cooperation of Pax2 and Pax5 in midbrain and cerebellum developmentThe B cell-specific transcription factor BSAP regulates B cell proliferation.An alternative splicing event in the Pax-3 paired domain identifies the linker region as a key determinant of paired domain DNA-binding activity.The Pax-5 gene is alternatively spliced during B-cell development.Pax8 has a key role in thyroid cell differentiation.The PAX258 gene subfamily: a comparative perspective.Identification and characterization of novel PAX8 mutations in Congenital Hypothyroidism(CH) in a Chinese population.Molecular basis of thyrotropin and thyroid hormone action during implantation and early development.DNA-binding and transactivation properties of Pax-6: three amino acids in the paired domain are responsible for the different sequence recognition of Pax-6 and BSAP (Pax-5).Dissection of the transactivation function of the transcription factor encoded by the eye developmental gene PAX6.Paired-Box genes are frequently expressed in cancer and often required for cancer cell survival.
P2860
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P2860
Alternative splicing of Pax-8 gene transcripts is developmentally regulated and generates isoforms with different transactivation properties
description
1993 nî lūn-bûn
@nan
1993 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1993 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
name
Alternative splicing of Pax-8 ...... ent transactivation properties
@ast
Alternative splicing of Pax-8 ...... ent transactivation properties
@en
Alternative splicing of Pax-8 ...... ent transactivation properties
@en-gb
Alternative splicing of Pax-8 ...... ent transactivation properties
@nl
type
label
Alternative splicing of Pax-8 ...... ent transactivation properties
@ast
Alternative splicing of Pax-8 ...... ent transactivation properties
@en
Alternative splicing of Pax-8 ...... ent transactivation properties
@en-gb
Alternative splicing of Pax-8 ...... ent transactivation properties
@nl
prefLabel
Alternative splicing of Pax-8 ...... ent transactivation properties
@ast
Alternative splicing of Pax-8 ...... ent transactivation properties
@en
Alternative splicing of Pax-8 ...... ent transactivation properties
@en-gb
Alternative splicing of Pax-8 ...... ent transactivation properties
@nl
P2093
P2860
P356
P1476
Alternative splicing of Pax-8 ...... ent transactivation properties
@en
P2093
M Busslinger
R Kurzbauer
P2860
P304
P356
10.1128/MCB.13.10.6024
P407
P577
1993-10-01T00:00:00Z