Liver X receptor activation controls intracellular cholesterol trafficking and esterification in human macrophages
about
Novel function of Niemann-Pick C1-like 1 as a negative regulator of Niemann-Pick C2 proteinThe nuclear receptor Rev-erbalpha is a liver X receptor (LXR) target gene driving a negative feedback loop on select LXR-induced pathways in human macrophagesLiver X receptors inhibit human monocyte-derived macrophage foam cell formation by inhibiting fluid-phase pinocytosis of LDLRab8-dependent recycling promotes endosomal cholesterol removal in normal and sphingolipidosis cellsLiver X receptors at the intersection of lipid metabolism and atherogenesisDifferent cellular traffic of LDL-cholesterol and acetylated LDL-cholesterol leads to distinct reverse cholesterol transport pathwaysStimulation of the liver X receptor pathway inhibits HIV-1 replication via induction of ATP-binding cassette transporter A1Adenosine monophosphate-activated protein kinase induces cholesterol efflux from macrophage-derived foam cells and alleviates atherosclerosis in apolipoprotein E-deficient mice.Lysosomal acid lipase: at the crossroads of normal and atherogenic cholesterol metabolismATP binding cassette G1-dependent cholesterol efflux during inflammation.Common ABCA1 variants, HDL levels, and cellular cholesterol efflux in subjects with familial low HDL.Dietary cholesterol, female gender and n-3 fatty acid deficiency are more important factors in the development of non-alcoholic fatty liver disease than the saturation index of the fatPhytosterols differentially influence ABC transporter expression, cholesterol efflux and inflammatory cytokine secretion in macrophage foam cells.The role of the Niemann-Pick disease, type C1 protein in adipocyte insulin action.Pharmacological suppression of hepcidin increases macrophage cholesterol efflux and reduces foam cell formation and atherosclerosis.Novel HDL-directed pharmacotherapeutic strategies.Lipoxin A4 promotes ABCA1 expression and cholesterol efflux through the LXRα signaling pathway in THP-1 macrophage-derived foam cells.Weekly Treatment of 2-Hydroxypropyl-β-cyclodextrin Improves Intracellular Cholesterol Levels in LDL Receptor Knockout MiceOn the role of skin in the regulation of local and systemic steroidogenic activities.Liver X receptors as integrators of metabolic and inflammatory signalingRole of the steroidogenic acute regulatory protein in health and disease.Targeting high density lipoproteins in the prevention of cardiovascular disease?Neuroprotection by cyclodextrin in cell and mouse models of Alzheimer diseaseMechanisms of action of hormone-sensitive lipase in mouse Leydig cells: its role in the regulation of the steroidogenic acute regulatory protein11β-hydroxysteroid dehydrogenase type 1 deficiency in bone marrow-derived cells reduces atherosclerosis.HDL, Atherosclerosis, and Emerging TherapiesClinically used selective estrogen receptor modulators affect different steps of macrophage-specific reverse cholesterol transport.Regulation of macrophage function in inflammation and atherosclerosisNiemann-Pick C2 (NPC2) and intracellular cholesterol trafficking.Synergistic activation of steroidogenic acute regulatory protein expression and steroid biosynthesis by retinoids: involvement of cAMP/PKA signalingSterol regulation of metabolism, homeostasis, and development.Simvastatin promotes NPC1-mediated free cholesterol efflux from lysosomes through CYP7A1/LXRα signalling pathway in oxLDL-loaded macrophages.Oxysterols in biological systems: the gastrointestinal tract, liver, vascular wall and central nervous system.Liver X receptor agonist T0901317 reduces atherosclerotic lesions in apoE-/- mice by up-regulating NPC1 expression.High-density lipoprotein-based drug discovery for treatment of atherosclerosis.Cigarette smoke affects ABCAl expression via liver X receptor nuclear translocation in human keratinocytes.Differential regulation of the STARD1 subfamily of START lipid trafficking proteins in human macrophages.Overexpression of STARD3 in human monocyte/macrophages induces an anti-atherogenic lipid phenotypeThe Drosophila DHR96 nuclear receptor binds cholesterol and regulates cholesterol homeostasisHuman atherosclerotic plaque alternative macrophages display low cholesterol handling but high phagocytosis because of distinct activities of the PPARγ and LXRα pathways.
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P2860
Liver X receptor activation controls intracellular cholesterol trafficking and esterification in human macrophages
description
2005 nî lūn-bûn
@nan
2005 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
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2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Liver X receptor activation co ...... ification in human macrophages
@ast
Liver X receptor activation co ...... ification in human macrophages
@en
Liver X receptor activation co ...... ification in human macrophages
@en-gb
Liver X receptor activation co ...... ification in human macrophages
@nl
type
label
Liver X receptor activation co ...... ification in human macrophages
@ast
Liver X receptor activation co ...... ification in human macrophages
@en
Liver X receptor activation co ...... ification in human macrophages
@en-gb
Liver X receptor activation co ...... ification in human macrophages
@nl
prefLabel
Liver X receptor activation co ...... ification in human macrophages
@ast
Liver X receptor activation co ...... ification in human macrophages
@en
Liver X receptor activation co ...... ification in human macrophages
@en-gb
Liver X receptor activation co ...... ification in human macrophages
@nl
P2093
P50
P921
P3181
P1433
P1476
Liver X receptor activation co ...... ification in human macrophages
@en
P2093
C Fontaine
E Rigamonti
G Chinetti-Gbaguidi
M A Bouhlel
P3181
P356
10.1161/01.RES.0000184678.43488.9F
P407
P577
2005-09-30T00:00:00Z