Two independent domains of hDlg are sufficient for subcellular targeting: the PDZ1-2 conformational unit and an alternatively spliced domain
about
Characterization of PDZ-binding kinase, a mitotic kinaseGAKIN, a novel kinesin-like protein associates with the human homologue of the Drosophila discs large tumor suppressor in T lymphocytesDiscs large (Dlg1) complexes in lymphocyte activationHuman homolog of disc-large is required for adherens junction assembly and differentiation of human intestinal epithelial cellsIdentification of mitogen-activated protein/extracellular signal-responsive kinase kinase 2 as a novel partner of the scaffolding protein human homolog of disc-largeHDLG5/KIAA0583, encoding a MAGUK-family protein, is a primary progesterone target gene in breast cancer cellsRegulation of the discs large tumor suppressor by a phosphorylation-dependent interaction with the beta-TrCP ubiquitin ligase receptorNHE3 kinase A regulatory protein E3KARP binds the epithelial brush border Na+/H+ exchanger NHE3 and the cytoskeletal protein ezrinHuman homologue of the Drosophila discs large tumor suppressor binds to p56lck tyrosine kinase and Shaker type Kv1.3 potassium channel in T lymphocytesEzrin tunes T-cell activation by controlling Dlg1 and microtubule positioning at the immunological synapse.PDZ domains: fundamental building blocks in the organization of protein complexes at the plasma membraneDirect interaction of CASK/LIN-2 and syndecan heparan sulfate proteoglycan and their overlapping distribution in neuronal synapsesYes-associated protein 65 localizes p62(c-Yes) to the apical compartment of airway epithelia by association with EBP50PDZ Domain Recognition: Insight from Human Tax-Interacting Protein 1 (TIP-1) Interaction with Target ProteinsStructural Insights into a Wildtype Domain of the Oncoprotein E6 and Its Interaction with a PDZ DomainMolecular cloning and characterization of Pals, proteins associated with mLin-7Protein trafficking and anchoring complexes revealed by proteomic analysis of inward rectifier potassium channel (Kir2.x)-associated proteinsPlasma membrane Ca2+ ATPase isoform 4b binds to membrane-associated guanylate kinase (MAGUK) proteins via their PDZ (PSD-95/Dlg/ZO-1) domainsThe human adenovirus E4-ORF1 protein subverts discs large 1 to mediate membrane recruitment and dysregulation of phosphatidylinositol 3-kinaseOncogenic function for the Dlg1 mammalian homolog of the Drosophila discs-large tumor suppressorAssociation of an A-kinase-anchoring protein signaling scaffold with cadherin adhesion molecules in neurons and epithelial cellsEssential function of protein 4.1G in targeting of membrane protein palmitoylated 6 into Schmidt-Lanterman incisures in myelinated nervesThe invasive capacity of HPV transformed cells requires the hDlg-dependent enhancement of SGEF/RhoG activity.The unique-5 and -6 motifs of ZO-1 regulate tight junction strand localization and scaffolding properties.Protein 4.1-mediated membrane targeting of human discs large in epithelial cells.The distribution and function of alternatively spliced insertions in hDlg.Synaptic targeting and localization of discs-large is a stepwise process controlled by different domains of the proteinOrganizing a functional junctional complex requires specific domains of the Drosophila MAGUK Discs large.Interdomain chaperoning between PSD-95, Dlg, and Zo-1 (PDZ) domains of glutamate receptor-interacting proteins.Human homologue of the Drosophila discs large tumor suppressor protein forms an oligomer in solution. Identification of the self-association site.Recent excitement in the ionotropic glutamate receptor field.Signaling pathways are focused at specialized regions of the plasma membrane by scaffolding proteins of the MAGUK family.Polarity protein complex Scribble/Lgl/Dlg and epithelial cell barriersThe MEK2-binding tumor suppressor hDlg is recruited by E-cadherin to the midbody ring.Selective phosphorylation of the Dlg1AB variant is critical for TCR-induced p38 activation and induction of proinflammatory cytokines in CD8+ T cells.Characterization of in vivo Dlg1 deletion on T cell development and functionMonoclonal antibody detection of CD46 clustering beneath Neisseria gonorrhoeae microcolonies.Dishevelled binds the Discs large 'Hook' domain to activate GukHolder-dependent spindle positioning in Drosophila.The scaffolding protein synapse-associated protein 97 is required for enhanced signaling through isotype-switched IgG memory B cell receptors.Unconventional myosins in inner-ear sensory epithelia
P2860
Q22253975-214553CD-DDC1-42CE-9E54-4A254B7E4A37Q22254279-A83D1812-9EF6-4814-83B3-A79AC159315DQ24299762-D953E89C-85A9-4DD6-8847-7D5DDC72B7B4Q24303623-A7AF75A1-5278-45C9-A925-B2DF44D9F3BCQ24304418-2D6E8045-B0D5-49F0-A986-8426B9308E2DQ24307837-57A82974-C86A-4469-ACBA-CD70A4C0C0DFQ24314190-6E20E01E-EF25-49CD-A038-54D4474609CAQ24315976-A32030E9-D4F5-4B5B-B089-25DD90CD06E1Q24319836-05D8D622-A80C-48B6-9079-B2F3082C7340Q24321953-36E2D67D-A48E-49D9-9020-C76A6C68F584Q24563377-192F5B49-FF30-4B77-95B5-FC8B7BB53EA9Q24682552-7E0A789A-C2D7-4BD1-8CBF-1AD3DCBEBBF0Q24683312-65CF906D-8C9E-475F-8330-5113DC2E963DQ27026437-24D15090-9A6F-4DD8-A6E2-EAE825E04596Q27677967-25D5D522-BC88-42D4-B314-6AD1F474E398Q28141228-655E51C8-0F4D-4484-A6B5-65152A1C9F85Q28250776-90A7BB08-8E7C-4C5A-9EB1-7808ADB8297CQ28259139-81E036B9-FB00-41FC-8481-4BB799B4DC47Q28538376-9E158219-0E08-4B70-A9C3-3393E122C04AQ28571122-8FEE22FA-2FD7-4D8D-8767-929321C3F861Q28576588-93620D19-197B-4CF2-8AA5-F0D9ADA1189DQ28587957-A75DDFD4-FECC-42D1-ABF6-AD9C281E0544Q30010159-0542E452-17C0-44FA-BA0F-7FA34B19B0BAQ30159513-8EFF9C2D-851F-48EE-A9C2-B3D5FA00B6EDQ30164681-F4BA145D-0C0F-4201-A34B-E6A943F3B3B8Q30167770-8064A3DF-D0B4-449F-9935-550467BB751CQ30168742-3925076F-5F3F-463B-8745-57B43F8596C3Q30176301-BA33205D-D1C3-4570-A04A-4715DAD5D154Q30660494-AA1D8C1C-C2D3-4B35-AF90-0E5DE5B064A9Q30864732-69AEF09D-FD60-4318-805C-25A778A0607EQ33691516-939446EB-8B29-4CF0-A6AC-7A19136FB38DQ33750222-35D17278-D844-4CFD-BE5E-1E0701F79C7EQ33966512-88EA4C87-B96C-47DB-B06B-B8C15EE051F9Q34106720-C6AE725C-14AD-4909-B417-4FB55A0A33D3Q34150054-98190EAF-1DA4-446F-99B0-9C39514AA6ADQ34428591-4CD7870A-1C96-46E4-9618-F6DAA10416C0Q34492866-F1A1490F-2F70-4E10-9D45-3A5F698F0C8AQ35475599-7A2383D5-85BF-4022-9C09-48088D8A26B8Q36145652-3E81ACA0-EECF-468E-8657-BE8AC084D142Q36254696-2F8DC2EA-CB7A-4ACE-A27C-667CA027910F
P2860
Two independent domains of hDlg are sufficient for subcellular targeting: the PDZ1-2 conformational unit and an alternatively spliced domain
description
1996 nî lūn-bûn
@nan
1996 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年学术文章
@wuu
1996年学术文章
@zh-cn
1996年学术文章
@zh-hans
1996年学术文章
@zh-my
1996年学术文章
@zh-sg
1996年學術文章
@yue
name
Two independent domains of hDl ...... n alternatively spliced domain
@ast
Two independent domains of hDl ...... n alternatively spliced domain
@en
Two independent domains of hDl ...... n alternatively spliced domain
@en-gb
Two independent domains of hDl ...... n alternatively spliced domain
@nl
type
label
Two independent domains of hDl ...... n alternatively spliced domain
@ast
Two independent domains of hDl ...... n alternatively spliced domain
@en
Two independent domains of hDl ...... n alternatively spliced domain
@en-gb
Two independent domains of hDl ...... n alternatively spliced domain
@nl
prefLabel
Two independent domains of hDl ...... n alternatively spliced domain
@ast
Two independent domains of hDl ...... n alternatively spliced domain
@en
Two independent domains of hDl ...... n alternatively spliced domain
@en-gb
Two independent domains of hDl ...... n alternatively spliced domain
@nl
P2093
P2860
P356
P1476
Two independent domains of hDl ...... n alternatively spliced domain
@en
P2093
P2860
P304
P356
10.1083/JCB.135.4.1125
P407
P577
1996-11-01T00:00:00Z